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Autor:
W C, Cole
Publikováno v:
The Buffalo medical journal and monthly review of medical and surgical science. 5(4)
Publikováno v:
Molecular Reproduction and Development. 74:1105-1112
While considerable information is available on the physiological effects of estrogen, much less is known about the regulation of estrogen receptor (ER) subtypes, particularly in non-mammalian vertebrates. Using goldfish as primary experimental model,
Publikováno v:
JAMA Dermatology. 152:1273
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 265:H1809-H1818
We previously demonstrated that ATP-sensitive K+ channels (KATP) protect the guinea pig myocardium against ischemia-reperfusion injury (Cole et al., Circ. Res. 69: 571-581, 1991), but the cellular alterations leading to ischemic injury affected by KA
Autor:
W. C. Cole, R I Jabr
Publikováno v:
Circulation Research. 72:1229-1244
Oxygen-derived free radicals (O-Rs) are thought to induce alterations in cardiac electrical activity; however, the underlying membrane ionic currents affected by O-Rs and the mechanisms by which O-Rs induce their effects on ion channels in the heart
Publikováno v:
The British journal of radiology. 77(914)
Ionizing radiation has proven to be a double-edged sword since its discovery by Dr Roentgen in 1895. Radiation is a potent mutagen and carcinogen; however, it is also used in the diagnosis and treatment of human diseases. Background radiation consist
Publikováno v:
Tennessee medicine : journal of the Tennessee Medical Association. 94(4)
Peripartum cardiomyopathy is an uncommon complication of human pregnancy that threatens both the mother and fetus with maternal congestive heart failure. Clinicians must be aware of this problem in order to provide prompt diagnosis and effective trea
Publikováno v:
British journal of pharmacology. 130(8)
In the presence of L-NNA (100 microM), indomethacin (10 microM) and ODQ (10 microM), acetylcholine induced a concentration-dependent vasorelaxation of guinea-pig mesenteric and middle cerebral arteries precontracted with cirazoline or histamine, but
Publikováno v:
In vitro cellulardevelopmental biology. Animal. 36(2)
Cyclosporin A is routinely used in transplant therapy following allogeneic or xenogeneic tissue transplantation to prevent rejection. This immunosuppressive drug is also neurotoxic; however, its mechanisms of action for neurotoxicity are poorly under