Zobrazeno 1 - 10
of 25
pro vyhledávání: '"W B Kinlaw"'
Publikováno v:
Endocrinology. 138(12)
Spot 14 (S14) is a nuclear protein that is abundant only in lipogenic tissues (liver, adipose, lactating mammary), where its expression is rapidly regulated by hormones and dietary constituents. We recently showed that S14 acts at the transcriptional
Publikováno v:
The Journal of biological chemistry. 272(4)
"Spot 14" protein appears rapidly in nuclei of hepatocytes exposed to glucose and thyroid hormone. Exposure of glucose- and T3-treated hepatocytes to a spot 14 antisense oligonucleotide inhibited induction of mRNAs encoding malic enzyme, ATP citrate-
Publikováno v:
The Journal of biological chemistry. 269(23)
The type I iodothyronine 5'-deiodinase (5'-DI) present in rat liver and kidney has recently been demonstrated to be a selenoprotein. The goal of the present study was to examine in detail the effect of selenium (Se) deficiency on 5'-DI at the protein
Publikováno v:
The American journal of medicine. 89(4)
Autor:
Lisa H. Fish, W B Kinlaw, Harold L. Schwartz, Ana Perez-Castillo, Cary N. Mariash, Jack H. Oppenheimer
Publikováno v:
Molecular Endocrinology. 1:609-613
The mRNA of the rat hepatic S14 gene accumulates rapidly after administration of T3 and carbohydrate, making it an excellent model for studies of the effects of dietary and hormonal stimuli at the hepatocellular level. We undertook studies to assess
Autor:
J W Breckenridge, W B Kinlaw
Publikováno v:
Journal of Computer Assisted Tomography. 4:392-397
Two cases demonstrating the computed tomographic appearance of azygos continuation of the inferior vena cava (IVC) are presented. One is associated with a retroaortic left renal vein and the other with a duplicated IVC. An enlarged azygos vein should
Publikováno v:
Journal of Biological Chemistry. 264:19784-19789
In rat liver, triiodothyronine (T3) and dietary carbohydrate induce the expression of the genes coding for malic enzyme (ME) (EC 1.1.1.40) and S14 protein. The mRNAs for both ME and S14 are elevated under circumstances associated with augmented lipog
Publikováno v:
Endocrinology. 123:2255-2260
The rapid response of hepatic mRNA-S14 to T3 has made this sequence an important model for studying the mechanism of hormonal induction of gene expression. In previous studies we showed, in the intact rat, that glucagon administration during the peak
Autor:
Cary N. Mariash, Harold L. Schwartz, Jack H. Oppenheimer, Hedley C. Freake, N. C. W. Wong, W B Kinlaw
Publikováno v:
Endocrine reviews. 8(3)
Introduction DESPITE the fact that the clinical and biological importance of the thyroid hormones have been recognized for approximately 100 yr (1–3), until recently our understanding of the biological effects of these hormones has been largely des
Publikováno v:
The Journal of clinical investigation. 74(6)
We have studied the hepatic messenger RNA (mRNA) activity profile in chronically azotemic rats and sought to determine whether the observed changes could be mediated either by reduced food intake or diminished thyroid function at the tissue level. mR