Zobrazeno 1 - 7
of 7
pro vyhledávání: '"W B, Mattes"'
Publikováno v:
Xenobiotica. 36:1081-1121
The goal of this study was to compare and contrast the basal gene expression levels of the various enzymes involved in glutathione metabolism among tissues and genders of the rat, mouse and canine. The approach taken was to use Affymetrix GeneChip mi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1293bc751251c177b105b2174032fc6f
https://doi.org/10.1080/00498250600861793
https://doi.org/10.1080/00498250600861793
Publikováno v:
British Journal of Cancer
The DNA damage and the sequence specificity of guanine-N7 alkylation produced by the novel, positively charged, antineoplastic agent 1,4-bis(2'-chloroethyl)-1,4-diazabicyclo-[2.2.1] heptane dimaleate (Dabis maleate) and its uncharged tertiary amine a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51e72433bc8e34868912fab3ae8670ff
https://doi.org/10.1038/bjc.1990.53
https://doi.org/10.1038/bjc.1990.53
Publikováno v:
Environmental and molecular mutagenesis. 33(3)
We compared the lambda cII/cI transgenic mutation assay described by Jakubczak et al. [(1996): Proc Natl Acad Sci USA 93:9073-9078] to the previously established Big Blue assay. Genomic DNA isolated from liver, spleen, and lung tissue of control or e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::99a8f49fff6295f24c353dc89eb361e9
https://pubmed.ncbi.nlm.nih.gov/10334627
https://pubmed.ncbi.nlm.nih.gov/10334627
Publikováno v:
Environmental and molecular mutagenesis. 33(2)
We tested the ability of a series of known genotoxic agents to cause mutations at the hprt locus in peripheral blood T-lymphocytes of cynomolgus monkeys as measured by the ability to form clones in the presence of 6-thioguanine. Ethylmethane sulfonat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::211633d49cc77820baa7149946172c51
https://pubmed.ncbi.nlm.nih.gov/10217066
https://pubmed.ncbi.nlm.nih.gov/10217066
Publikováno v:
Environmental and molecular mutagenesis. 33(2)
Big Blue mice harbor a recoverable transgene in a lambda/LIZ shuttle vector. In the standard assay, in vivo mutations are measured in the bacterial lacI gene using a labor-intensive color plaque assay. Applying a simpler assay [Jakubczak et al. (1996
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c6c7cdb6cf430527c2f4b5e70a2c59fc
https://pubmed.ncbi.nlm.nih.gov/10217067
https://pubmed.ncbi.nlm.nih.gov/10217067
Publikováno v:
Environmental and molecular mutagenesis. 32(4)
We examined several experimental parameters of the lambda cI/cII transgenic mutation assay. In the assay, clear plaque lambda phage mutants are identified in a positive selection scheme following rescue of the lambda/LIZ shuttle vector from frozen ti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::679815f0edcf97a6738a0604729f4a70
https://pubmed.ncbi.nlm.nih.gov/9882006
https://pubmed.ncbi.nlm.nih.gov/9882006
Publikováno v:
Acta oncologica (Stockholm, Sweden). 27(5)
An examination of the DNA sequence specificity of guanine-N7 alkylation for nitrogen mustards and chlorethylnitrosoureas revealed that large variations in alkylation intensities existed among different guanines in the DNA sequence. The most striking
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b81e745b773fffea555d5e101989724f
https://pubmed.ncbi.nlm.nih.gov/2849464
https://pubmed.ncbi.nlm.nih.gov/2849464