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Heptad motifs within the distal subdomain of the coiled-coil rod region of M protein from rheumatic fever and nephritis associated serotypes of group A streptococci are distinct from each other: Nucleotide sequence of the M57 gene and relation of the deduced amino acid sequence to other M proteins

Autor: Belur N. Manjula, K M Khandke, Thomas Fairwell, W A Relf, K S Sriprakash

Publikováno v: Journal of Protein Chemistry. 10:369-384

Streptococcal M protein, a dimeric alpha helical coiled-coil molecule, is an antigenically variable virulence factor on the surface of the bacteria. Our recent conformational analysis of the complete sequence of the M6 protein led us to propose a bas

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::646a069a02db00cc9375b06cd6cb7043
https://doi.org/10.1007/bf01025251

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Mapping a conserved conformational epitope from the M protein of group A streptococci

Autor: W A, Relf, J, Cooper, E R, Brandt, W A, Hayman, R F, Anders, S, Pruksakorn, B, Currie, A, Saul, M F, Good

Publikováno v: Peptide research. 9(1)

The carboxyl terminus of the M protein of group A streptococci (GAS) is highly conserved and contains epitopes that have been shown to induce opsonic antibodies and protection against GAS infection. This region of the protein can also stimulate T cel

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::380402104bea4ecd7ada148e40f3f917
https://pubmed.ncbi.nlm.nih.gov/8727479

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Imported malaria in Australia

Autor: R E, Boreham, W A, Relf

Publikováno v: The Medical journal of Australia. 155(11-12)

To obtain information on imported malaria in Australia.Patients with malaria diagnosed by microscopy by laboratories in southeast Queensland and northern New South Wales between October 1987 and December 1988 were included in this study. The chi 2 te

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::c8f99e5222b6fd43ab09652583349691
https://pubmed.ncbi.nlm.nih.gov/1745165

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Limited repertoire of the C-terminal region of the M protein in Streptococcus pyogenes

Autor: W A, Relf, K S, Sriprakash

Publikováno v: FEMS microbiology letters. 59(3)

We have amplified genomic sequences (emm) that may encode M protein from strains of Streptococcus pyogenes using the polymerase chain reaction (PCR). Genomic DNA from 22 isolates representing 14 M serotypes was selected for the study. Primers which c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::4b84eca1b28e9443580d51b20740b043
https://pubmed.ncbi.nlm.nih.gov/1980254

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Identification of sequence types among the M-nontypeable group A streptococci

Autor: W A Relf, K S Sriprakash, D R Martin

Publikováno v: Scopus-Elsevier

Streptococcal diseases, namely, acute glomerulonephritis and acute rheumatic fever, are common features in the aboriginal population of the Northern Territory of Australia. We examined the group A streptococcal M types identified during various surve

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01b48e9be2788b5d7f03301372edfacc
http://www.scopus.com/inward/record.url?eid=2-s2.0-0026486916&partnerID=MN8TOARS

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