Zobrazeno 1 - 10
of 131
pro vyhledávání: '"Władysława A, Daniel"'
Publikováno v:
Metabolites, Vol 13, Iss 5, p 629 (2023)
Tryptophan is metabolized along three main metabolic pathways, namely the kynurenine, serotonin and indole pathways. The majority of tryptophan is transformed via the kynurenine pathway, catalyzed by tryptophan-2,3-dioxygenase or indoleamine-2,3-diox
Externí odkaz:
https://doaj.org/article/3c99b56064c24a468bca04d62379436c
Publikováno v:
Cells, Vol 11, Iss 21, p 3513 (2022)
The aim of this work was to study the effect of prolonged lurasidone administration on the cytochrome 2D (CYP2D) expression and activity in the rat liver and selected brain structures involved in the therapeutic or side effects of this neuroleptic. M
Externí odkaz:
https://doaj.org/article/3529551fc93d4e0bb417af13877e7f19
Publikováno v:
Cells, Vol 10, Iss 12, p 3472 (2021)
CYP2D enzymes engage in the synthesis of endogenous neuroactive substances (dopamine, serotonin) and in the metabolism of neurosteroids. The present work investigates the effect of iloperidone on CYP2D enzyme expression and activity in rat brains and
Externí odkaz:
https://doaj.org/article/c1a123288cef4b5f8a7721e5dca3eff3
Autor:
Ewa Bromek, Anna Haduch, Marta Rysz, Joanna Jastrzębska, Renata Pukło, Olga Wójcikowska, Przemysław Jan Danek, Władysława Anna Daniel
Publikováno v:
Pharmaceutics, Vol 13, Iss 10, p 1643 (2021)
Recent research indicates that selective NMDA receptor GluN2B subunit antagonists may become useful for the treatment of major depressive disorders. We aimed to examine in parallel the effect of the selective NMDA receptor GluN2B subunit antagonist C
Externí odkaz:
https://doaj.org/article/8d90baaf32da49e78413385ceca134eb
Publikováno v:
Pharmaceuticals, Vol 14, Iss 7, p 629 (2021)
Therapy of schizophrenia requires long-term treatment with a relevant antipsychotic drug to achieve a therapeutic effect. The aim of the present study was to investigate the influence of prolonged treatment with the atypical neuroleptic asenapine on
Externí odkaz:
https://doaj.org/article/6ea8382ebbb741d9bdf09f02e94eda05
Autor:
Anna Haduch, Ewa Bromek, Renata Pukło, Joanna Jastrzębska, Przemysław Jan Danek, Władysława Anna Daniel
Publikováno v:
International Journal of Molecular Sciences; Volume 23; Issue 22; Pages: 13746
The CYP2D enzymes of the cytochrome P450 superfamily play an important role in psychopharmacology, since they are engaged in the metabolism of psychotropic drugs and endogenous neuroactive substrates, which mediate brain neurotransmission and the the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b3a5541260e63e63792e04a696e3461
Autor:
Władysława A. Daniel, Paulina Surówka, Patrycja Kleczkowska, Magdalena Zadrożny-Bujalska, Joanna Jastrzębska, Renata Pieniążek, Agata Suder, Renata Pukło, Małgorzata Filip, Małgorzata Frankowska
Publikováno v:
Pharmacological Reports
Background Opioid use disorders are serious contributors to the harms associated with the drug use. Unfortunately, therapeutic interventions for opioid addicts after detoxification have been limited and not sufficiently effective. Recently, several s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2fc6a7794db62a1f691ef1d70f2dec0d
https://doi.org/10.1007/s43440-021-00307-2
https://doi.org/10.1007/s43440-021-00307-2
Autor:
Ewa Bromek, Przemysław Jan Danek, Jacek Wójcikowski, Agnieszka Basińska-Ziobroń, Renata Pukło, Joanna Solich, Marta Dziedzicka-Wasylewska, Władysława Anna Daniel
Publikováno v:
Pharmacological reports : PR. 74(5)
Background Our earlier studies have shown that the brain noradrenergic system regulates cytochrome P450 (CYP) in rat liver via neuroendocrine mechanism. In the present work, a comparative study on the effect of intraperitoneal administration of the n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3f23e2a71dc6263191fed90a17075c4
https://pubmed.ncbi.nlm.nih.gov/36018449
https://pubmed.ncbi.nlm.nih.gov/36018449
Autor:
Renata Pukło, Magdalena Łasoń, Władysława A. Daniel, Mariusz Papp, Ewa Bromek, Anna Haduch, Marta Rysz, Monika Niemczyk, Piotr Gruca
Publikováno v:
Pharmacological Reports
Background The aim of our research was to determine the effects of chronic treatment with the atypical antidepressant agomelatine on the expression and activity of liver cytochrome P450 (CYP) in the chronic mild stress (CMS) model of depression, and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2216ae0df0c5f2929d8d75e05337bb41
https://doi.org/10.1007/s43440-020-00151-w
https://doi.org/10.1007/s43440-020-00151-w
Publikováno v:
Pharmacological Reports
Background The present study aimed at examining the inhibitory effect of two atypical neuroleptics iloperidone and lurasidone on the main human cytochrome P450 (CYP) enzymes in pooled human liver microsomes and cDNA-expressed CYP enzymes (supersomes)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb9ab186cd34062e09d7ac60f4b6d90d
https://doi.org/10.1007/s43440-020-00102-5
https://doi.org/10.1007/s43440-020-00102-5