Disease severity, arrhythmogenesis, and fibrosis are related to longer action potentials in tetralogy of Fallot.

Autor: Fürniss HE; Institute for Experimental Cardiovascular Medicine, Faculty of Medicine, University Heart Center Freiburg-Bad Krozingen, University of Freiburg, Freiburg, Germany. hannah.fuerniss@uniklinik-freiburg.de.; Department of Congenital Heart Defects and Pediatric Cardiology, Faculty of Medicine, University Heart Center Freiburg-Bad Krozingen, University of Freiburg, Mathildenstr. 1, 79106, Freiburg, Germany. hannah.fuerniss@uniklinik-freiburg.de., Wülfers EM; Institute for Experimental Cardiovascular Medicine, Faculty of Medicine, University Heart Center Freiburg-Bad Krozingen, University of Freiburg, Freiburg, Germany.; Department of Physics and Astronomy, Ghent University, Ghent, Belgium., Iaconianni P; Institute for Experimental Cardiovascular Medicine, Faculty of Medicine, University Heart Center Freiburg-Bad Krozingen, University of Freiburg, Freiburg, Germany., Ravens U; Institute for Experimental Cardiovascular Medicine, Faculty of Medicine, University Heart Center Freiburg-Bad Krozingen, University of Freiburg, Freiburg, Germany., Kroll J; Department of Cardiovascular Surgery, Faculty of Medicine, University Heart Center Freiburg-Bad Krozingen, University of Freiburg, Freiburg, Germany., Stiller B; Department of Congenital Heart Defects and Pediatric Cardiology, Faculty of Medicine, University Heart Center Freiburg-Bad Krozingen, University of Freiburg, Mathildenstr. 1, 79106, Freiburg, Germany., Kohl P; Institute for Experimental Cardiovascular Medicine, Faculty of Medicine, University Heart Center Freiburg-Bad Krozingen, University of Freiburg, Freiburg, Germany.; Signaling Research Centers BIOSS and CIBSS, University of Freiburg, Freiburg, Germany., Rog-Zielinska EA; Institute for Experimental Cardiovascular Medicine, Faculty of Medicine, University Heart Center Freiburg-Bad Krozingen, University of Freiburg, Freiburg, Germany., Peyronnet R; Institute for Experimental Cardiovascular Medicine, Faculty of Medicine, University Heart Center Freiburg-Bad Krozingen, University of Freiburg, Freiburg, Germany.

Publikováno v: Clinical research in cardiology : official journal of the German Cardiac Society [Clin Res Cardiol] 2024 May; Vol. 113 (5), pp. 716-727. Date of Electronic Publication: 2023 Sep 19.

Directed Graph Mapping exceeds Phase Mapping for the detection of simulated 2D meandering rotors in fibrotic tissue with added noise.

Autor: Lootens S; Department of Physics and Astronomy, Ghent University, Ghent, Belgium. Electronic address: sebastiaan.lootens@ugent.be., Janssens I; Department of Physics and Astronomy, Ghent University, Ghent, Belgium., Van Den Abeele R; Department of Physics and Astronomy, Ghent University, Ghent, Belgium., Wülfers EM; Department of Physics and Astronomy, Ghent University, Ghent, Belgium., Bezerra AS; Department of Physics and Astronomy, Ghent University, Ghent, Belgium., Verstraeten B; Department of Physics and Astronomy, Ghent University, Ghent, Belgium., Hendrickx S; Department of Physics and Astronomy, Ghent University, Ghent, Belgium., Okenov A; Department of Physics and Astronomy, Ghent University, Ghent, Belgium., Nezlobinsky T; Department of Physics and Astronomy, Ghent University, Ghent, Belgium., Panfilov AV; Department of Physics and Astronomy, Ghent University, Ghent, Belgium; World-Class Research Center 'Digital Biodesign and personalised healthcare', Sechenov University, Moscow 119991, Russia; Laboratory of Computational Biology and Medicine, Ural Federal University, Ekaterinburg 620002, Russia., Vandersickel N; Department of Physics and Astronomy, Ghent University, Ghent, Belgium.

Publikováno v: Computers in biology and medicine [Comput Biol Med] 2024 Mar; Vol. 171, pp. 108138. Date of Electronic Publication: 2024 Feb 16.

Directed graph mapping shows rotors maintain non-terminating and focal sources maintain self-terminating Torsade de Pointes in canine model.

Autor: Van Den Abeele R; Biophysics Group, Department of Physics and Astronomy, Faculty of Sciences, Ghent University, Ghent, Belgium., Hendrickx S; Biophysics Group, Department of Physics and Astronomy, Faculty of Sciences, Ghent University, Ghent, Belgium., Van Nieuwenhuyse E; Biophysics Group, Department of Physics and Astronomy, Faculty of Sciences, Ghent University, Ghent, Belgium., Dunnink A; Department of Medical Physiology, University Medical Center Utrecht, Utrecht, Netherlands., Panfilov AV; Biophysics Group, Department of Physics and Astronomy, Faculty of Sciences, Ghent University, Ghent, Belgium.; Laboratory of Computational Biology and Medicine, Ural Federal University, Yekaterinburg, Russia.; World-Class Research Center 'Digital Biodesign and Personalized Healthcare', Sechenov University, Moscow, Russia., Vos MA; Department of Medical Physiology, University Medical Center Utrecht, Utrecht, Netherlands., Wülfers EM; Biophysics Group, Department of Physics and Astronomy, Faculty of Sciences, Ghent University, Ghent, Belgium., Vandersickel N; Biophysics Group, Department of Physics and Astronomy, Faculty of Sciences, Ghent University, Ghent, Belgium.

Publikováno v: Frontiers in physiology [Front Physiol] 2023 Jul 26; Vol. 14, pp. 1201260. Date of Electronic Publication: 2023 Jul 26 (Print Publication: 2023).

Docosahexaenoic acid normalizes QT interval in long QT type 2 transgenic rabbit models in a genotype-specific fashion.

Autor: Castiglione A; Department of Cardiology and Angiology I, University Heart Center Freiburg, Medical Faculty, University of Freiburg, Freiburg, Germany.; Translational Cardiology, Department of Cardiology, Inselspital, Bern University Hospital, University of Bern, Buehlplatz 5, CH-3012 Bern, Switzerland.; Department of Translational Cardiology/Electrophysiology, Institute of Physiology, University of Bern, Bern, Switzerland., Hornyik T; Department of Cardiology and Angiology I, University Heart Center Freiburg, Medical Faculty, University of Freiburg, Freiburg, Germany.; Translational Cardiology, Department of Cardiology, Inselspital, Bern University Hospital, University of Bern, Buehlplatz 5, CH-3012 Bern, Switzerland.; Department of Translational Cardiology/Electrophysiology, Institute of Physiology, University of Bern, Bern, Switzerland.; Institute of Experimental Cardiovascular Medicine, University Heart Center Freiburg-Bad Krozingen, Medical Faculty, University of Freiburg, Freiburg, Germany.; Department of Pharmacology and Pharmacotherapy, University of Szeged, Szeged, Hungary., Wülfers EM; Institute of Experimental Cardiovascular Medicine, University Heart Center Freiburg-Bad Krozingen, Medical Faculty, University of Freiburg, Freiburg, Germany., Giammarino L; Translational Cardiology, Department of Cardiology, Inselspital, Bern University Hospital, University of Bern, Buehlplatz 5, CH-3012 Bern, Switzerland.; Department of Translational Cardiology/Electrophysiology, Institute of Physiology, University of Bern, Bern, Switzerland., Edler I; Department of Biomedical and Clinical Sciences, Linköping University, Linköping, Sweden., Jowais JJ; Department of Physiology and Biophysics, University of Miami, Miami, FL, USA., Rieder M; Department of Cardiology and Angiology I, University Heart Center Freiburg, Medical Faculty, University of Freiburg, Freiburg, Germany.; Translational Cardiology, Department of Cardiology, Inselspital, Bern University Hospital, University of Bern, Buehlplatz 5, CH-3012 Bern, Switzerland.; Department of Translational Cardiology/Electrophysiology, Institute of Physiology, University of Bern, Bern, Switzerland., Perez-Feliz S; Department of Cardiology and Angiology I, University Heart Center Freiburg, Medical Faculty, University of Freiburg, Freiburg, Germany.; Institute of Experimental Cardiovascular Medicine, University Heart Center Freiburg-Bad Krozingen, Medical Faculty, University of Freiburg, Freiburg, Germany., Koren G; Division of Cardiology, Cardiovascular Research Center, Brown University, Providence, RI, USA., Bősze Z; Animal Biotechnology Department, NARIC Agricultural Biotechnology Institute, Gödöllő, Hungary., Varró A; Department of Pharmacology and Pharmacotherapy, University of Szeged, Szeged, Hungary., Zehender M; Department of Cardiology and Angiology I, University Heart Center Freiburg, Medical Faculty, University of Freiburg, Freiburg, Germany., Brunner M; Department of Cardiology and Angiology I, University Heart Center Freiburg, Medical Faculty, University of Freiburg, Freiburg, Germany.; Department of Cardiology and Medical Intensive Care, St. Josefskrankenhaus, Freiburg, Germany., Bode C; Department of Cardiology and Angiology I, University Heart Center Freiburg, Medical Faculty, University of Freiburg, Freiburg, Germany., Liin SI; Department of Biomedical and Clinical Sciences, Linköping University, Linköping, Sweden., Larsson HP; Department of Physiology and Biophysics, University of Miami, Miami, FL, USA., Baczkó I; Department of Pharmacology and Pharmacotherapy, University of Szeged, Szeged, Hungary., Odening KE; Department of Cardiology and Angiology I, University Heart Center Freiburg, Medical Faculty, University of Freiburg, Freiburg, Germany.; Translational Cardiology, Department of Cardiology, Inselspital, Bern University Hospital, University of Bern, Buehlplatz 5, CH-3012 Bern, Switzerland.; Department of Translational Cardiology/Electrophysiology, Institute of Physiology, University of Bern, Bern, Switzerland.

Publikováno v: Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology [Europace] 2022 Mar 02; Vol. 24 (3), pp. 511-522.

A Fully-Coupled Electro-Mechanical Whole-Heart Computational Model: Influence of Cardiac Contraction on the ECG.

Autor: Moss R; Institute for Experimental Cardiovascular Medicine, University Heart Center Freiburg - Bad Krozingen, Medical Center-University of Freiburg, Freiburg, Germany.; Faculty of Medicine, University of Freiburg, Freiburg, Germany., Wülfers EM; Institute for Experimental Cardiovascular Medicine, University Heart Center Freiburg - Bad Krozingen, Medical Center-University of Freiburg, Freiburg, Germany.; Faculty of Medicine, University of Freiburg, Freiburg, Germany., Schuler S; Institute of Biomedical Engineering, Karlsruhe Institute of Technology (KIT), Karlsruhe, Germany., Loewe A; Institute of Biomedical Engineering, Karlsruhe Institute of Technology (KIT), Karlsruhe, Germany., Seemann G; Institute for Experimental Cardiovascular Medicine, University Heart Center Freiburg - Bad Krozingen, Medical Center-University of Freiburg, Freiburg, Germany.; Faculty of Medicine, University of Freiburg, Freiburg, Germany.

Publikováno v: Frontiers in physiology [Front Physiol] 2021 Dec 16; Vol. 12, pp. 778872. Date of Electronic Publication: 2021 Dec 16 (Print Publication: 2021).