Zobrazeno 1 - 10
of 25
pro vyhledávání: '"W, Vanherck"'
Autor:
W, Distelmans, R, Van Ginckel, W, Vanherck, R, Willebrords, L, Wouters, M, De Brabander, J, Mesens
Publikováno v:
Anticancer research. 11(1)
The clinically applicable formulation of the microtubule inhibitor erbulozole (R 55 104), dissolved into an aqueous hydroxypropyl-beta-cyclodextrin solution (designated as R 55 104-CYCLO), exerts a similar effect on growth delay of subcutaneous MO4 f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f8a43443264f95ebfddb41dedc7440ce
https://pubmed.ncbi.nlm.nih.gov/2018359
https://pubmed.ncbi.nlm.nih.gov/2018359
Autor:
Els Jagers, P. A. J. Janssen, R. De Coster, N. Goeminne, W. Wouters, Luc Wouters, W. Distelmans, R. Van Ginckel, W. Vanherck, R. Der Van Veer, H. Van Cauteren
Publikováno v:
The Prostate. 16(4)
The antitumoral activity of a novel imidazole derivative, R 75,251, has been studied in the androgen-dependent R3327G Dunning prostate adenocarcinoma grafted subcutaneously in syngeneic rats. Dietary application resulting approximately in dose levels
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c17b2f83f7146b1f570e7f6a44549800
https://pubmed.ncbi.nlm.nih.gov/2371176
https://pubmed.ncbi.nlm.nih.gov/2371176
Autor:
M. De Brrabander, R. Willebrords, R. Van Ginckel, W. Distelmans, Jan Heeres, W. Vanherck, Luc Wouters
Publikováno v:
European Journal of Cancer and Clinical Oncology. 25:1499-1504
Erbulozole (P.I.N.N.) (R 55 104) is a more water soluble congener of the synthetic microtubule inhibitor tubulozole (R 46 846) exhibiting a reversible antimicrotubular activity in vitro at a dose (1.56 x 10(-8) M) which is at least 10-fold lower. The
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fefbfbb0cb1257a30c94454e726aa17c
https://doi.org/10.1016/0277-5379(89)90111-9
https://doi.org/10.1016/0277-5379(89)90111-9
Akademický článek
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Publikováno v:
European journal of cancerclinical oncology. 20(1)
Tubulazole, a new synthetic microtubule inhibitor in vitro, is tested in vivo upon three experimental neoplasms: MO4 sarcoma, L1210 leukemia and TA3 carcinoma. The compound is tested using different treatment schedules upon different inoculation rout
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::187eb136a8a2089fba22934316810024
https://pubmed.ncbi.nlm.nih.gov/6537919
https://pubmed.ncbi.nlm.nih.gov/6537919
Publikováno v:
Anticancer research. 6(4)
Implantation of fragments from subcutaneously grown Lewis lung carcinoma 3LL under the renal capsule of syngeneic mice results in invasion of the kidney parenchyma. The synthetic microtubule inhibitor tubulozole blocks or decreases this malignant inv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::79459486a8605328ce143368ed9f2841
https://pubmed.ncbi.nlm.nih.gov/3752948
https://pubmed.ncbi.nlm.nih.gov/3752948
Autor:
Robert Van Ginckel, Marc De Brabander, W. Distelmans, Luc Wouters, Pierre Van Den Winkel, W. Vanherck, Guy De Backer, R. Willebrords
Publikováno v:
International journal of radiation oncology, biology, physics. 16(1)
The combined effect of the microtubule inhibitor tubulozole and gamma-irradiation has been investigated in vivo in subcutaneous MO4 fibrosarcomas and Lewis Lung carcinomas. A marked interactive effect on tumor growth was observed when 160 mg/kg tubul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea4117bfd022049f70f7079be5b0c1c9
https://pubmed.ncbi.nlm.nih.gov/2912940
https://pubmed.ncbi.nlm.nih.gov/2912940
Publikováno v:
Invasionmetastasis. 5(3)
When MO4 tumor fragments were implanted under the renal capsule of syngeneic or allogeneic mice, invasion of the renal parenchyma was observed. Inhibition of invasion by the microtubule inhibitor tubulozole could be macroscopically quantified and com
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f7f5d15501f2afb8893e6e56723b1901
https://pubmed.ncbi.nlm.nih.gov/3997412
https://pubmed.ncbi.nlm.nih.gov/3997412
Akademický článek
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Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.