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Autor:
Michael V. Murray, An Boudrez, Monique Beullens, I Jagiello, Adrian R. Krainer, V Vulsteke, W Stalmans, A Van Eynde, Mathieu Bollen, Peter M.A. Groenen
Publikováno v:
Journal of Biological Chemistry. 275:25411-25417
NIPP1 is a regulatory subunit of a species of protein phosphatase-1 (PP1) that co-localizes with splicing factors in nuclear speckles. We report that the N-terminal third of NIPP1 largely consists of a Forkhead-associated (FHA) protein interaction do
Publikováno v:
Diabetes. 45:980-983
Autor:
Keith Biggadike, Kathryn H. Smelt, Matthias Mueller, C. R. Veighey, Alexandra L. Lane, David J. Watkin, Yves Blériot, George W. J. Fleet, J. Cadefau, W. Stalmans
Publikováno v:
ChemInform. 28
Autor:
Louise N. Johnson, W. Stalmans, Kathryn H. Smelt, Mathieu Bollen, Nikos G. Oikonomakos, David J. Watkin, Keith Biggadike, Sarah Crook, Joan A. Cadefau, Alexandra L. Lane, Yves Blériot, George W. J. Fleet
Publikováno v:
ChemInform. 28
Short efficient syntheses of epimeric C6- C -methyl glucoses are described. One C-6 epimer activates glycogen synthase while the other epimer inactivates the enzyme; C6 R -C-methyl glucose 3 is the first example of a specific inhibitor of glucose-6-p
Autor:
M. Bollen, W. Stalmans
Publikováno v:
Current Opinion in Gastroenterology. 6:412-417
Publikováno v:
The Biochemical journal. 360(Pt 2)
Hepatic glycogen synthesis is impaired in insulin-dependent diabetic rats owing to defective activation of glycogen synthase by glycogen-bound protein phosphatase 1 (PP1). The identification of three glycogen-targetting subunits in liver, G(L), R5/PT
Publikováno v:
NMR in biomedicine. 12(3)
Inhibition of hormone-stimulated hepatic glycogenolysis by fructose (Fru) has been attributed to accumulation of the competitive inhibitor Fru1P and/or to the associated depletion of the substrate phosphate (Pi). To evaluate the relative importance o
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 93
Autor:
Kathryn H. Smelt, Mathieu Bollen, Yves Blériot, Joan A. Cadefau, David J. Watkin, Alexandra L. Lane, Louise N. Johnson, George W. J. Fleet, Keith Biggadike, Nikos G. Oikonomakos, W. Stalmans, Sarah Crook
Publikováno v:
Tetrahedron Letters 37:39(Sep1996):7155-7158
Short efficient syntheses of epimeric C6- C -methyl glucoses are described. One C-6 epimer activates glycogen synthase while the other epimer inactivates the enzyme; C6 R -C-methyl glucose 3 is the first example of a specific inhibitor of glucose-6-p