Zobrazeno 1 - 10
of 733
pro vyhledávání: '"W, Mulder"'
Autor:
Arjan F Theil, Alex Pines, Tuğba Kalayci, José M Heredia‐Genestar, Anja Raams, Marion H Rietveld, Sriram Sridharan, Sabine EJ Tanis, Klaas W Mulder, Nesimi Büyükbabani, Birsen Karaman, Zehra O Uyguner, Hülya Kayserili, Jan HJ Hoeijmakers, Hannes Lans, Jeroen AA Demmers, Joris Pothof, Umut Altunoglu, Abdoelwaheb El Ghalbzouri, Wim Vermeulen
Publikováno v:
EMBO Molecular Medicine, Vol 15, Iss 11, Pp 1-27 (2023)
Abstract The brittle hair syndrome Trichothiodystrophy (TTD) is characterized by variable clinical features, including photosensitivity, ichthyosis, growth retardation, microcephaly, intellectual disability, hypogonadism, and anaemia. TTD‐associate
Externí odkaz:
https://doaj.org/article/00a4d41179d0455f867ed390b4be7d8b
Autor:
Joris J. Carmiggelt, Iacopo Bertelli, Roland W. Mulder, Annick Teepe, Mehrdad Elyasi, Brecht G. Simon, Gerrit E. W. Bauer, Yaroslav M. Blanter, Toeno van der Sar
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-6 (2023)
Electron spins in diamond allow magnetometry with high sensitivity, but the bandwidth in the microwave regime is limited to a narrow band around their resonance frequency. Here, the authors solve this problem by coupling the spins to a thin film of y
Externí odkaz:
https://doaj.org/article/1003d2de741643ed82697a7cc4622030
Autor:
Wikus W. Mulder, MBChB, MMed (Surg), FCS (SA), Emmanuel Arko-Cobbah, MBChB, MMed (Surg), Cert Trauma Surgery (SA), Gina Joubert, MSc
Publikováno v:
Surgery Open Science, Vol 11, Iss , Pp 62-68 (2023)
Background: The study aimed to calculate the predictive value of admission laboratory values in patients with perforated peptic ulcers. Methods: A retrospective, cohort analytical, observational study was performed, including patients with surgically
Externí odkaz:
https://doaj.org/article/2e04bcb71db24e8183725151fdd267c7
Publikováno v:
Frontiers in Catalysis, Vol 2 (2022)
Hydrogen is a clean, renewable energy source, that when combined with oxygen, produces heat and electricity with only water vapor as a biproduct. Furthermore, it has the highest energy content by weight of all known fuels. As a result, various strate
Externí odkaz:
https://doaj.org/article/1a37f37037de40c38fee2f7ad1517c4e
Publikováno v:
Frontiers in Microbiology, Vol 13 (2022)
The [FeFe]-hydrogenases are enzymes that catalyze the reversible activation of H2 coupled to the reduction–oxidation of electron carriers. Members of the different taxonomic groups of [FeFe]-hydrogenases display a wide range of preference, or bias,
Externí odkaz:
https://doaj.org/article/8a7a6840c5524042a636565e6c7b0af4
Autor:
Georgina Peñalosa-Ruiz, Vicky Bousgouni, Jan P. Gerlach, Susan Waarlo, Joris V. van de Ven, Tim E. Veenstra, José C.R. Silva, Simon J. van Heeringen, Chris Bakal, Klaas W. Mulder, Gert Jan C. Veenstra
Publikováno v:
Stem Cell Reports, Vol 12, Iss 4, Pp 743-756 (2019)
Summary: Differentiated cells are epigenetically stable, but can be reprogrammed to pluripotency by expression of the OSKM transcription factors. Despite significant effort, relatively little is known about the cellular requirements for reprogramming
Externí odkaz:
https://doaj.org/article/51f683d499ae437386ac566ebd0aef86
Publikováno v:
PeerJ, Vol 8, p e8952 (2020)
Reprogramming somatic cells to induced pluripotent stem cells (iPSC) succeeds only in a small fraction of cells within the population. Reprogramming occurs in distinctive stages, each facing its own bottlenecks. It initiates with overexpression of tr
Externí odkaz:
https://doaj.org/article/f3730b8caa664dcca0f8bc305b101e18
Autor:
Roderick A.P.M. van Eijl, Jessie A.G.L. van Buggenum, Sabine E.J. Tanis, Joost Hendriks, Klaas W. Mulder
Publikováno v:
iScience, Vol 9, Iss , Pp 412-422 (2018)
Summary: Epidermal homeostasis requires balanced and coordinated adult stem cell renewal and differentiation. These processes are controlled by both extracellular signaling and by cell intrinsic transcription regulatory networks, yet how these contro
Externí odkaz:
https://doaj.org/article/376135bc88fd479f858ecc4285c222e9
Autor:
Jessie A. G. van Buggenum, Jan P. Gerlach, Sabine E. J. Tanis, Mark Hogeweg, Pascal W. T. C. Jansen, Jesse Middelwijk, Ruud van der Steen, Michiel Vermeulen, Hendrik G. Stunnenberg, Cornelis A. Albers, Klaas W. Mulder
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-11 (2018)
Detecting proteins and post-translational modifications is important for drug screens, but the number of proteins measurable simultaneously is limited. Here the authors use antibodies tagged with DNA barcodes and high-throughput sequencing to detect
Externí odkaz:
https://doaj.org/article/aee29dc4444b4d96b9ebc997bd57935e
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-11 (2017)
Abstract In this study, we originally aimed to characterize the potential role of Argonaute 2 (AGO2) in the nucleus, a key protein of the miRNA machinery. We combined Chromatin Immunoprecipitation (ChIP) with high throughput sequencing (ChIP-seq) and
Externí odkaz:
https://doaj.org/article/9349e82891754ac5af58d4cce70e19dc