Zobrazeno 1 - 10
of 87
pro vyhledávání: '"W, Modi"'
Autor:
Gary K. Steinberg, Nariman Panahian, Miguel A. Pérez-Pinzón, Guo-Hua Sun, Marlene W. Modi, Jerry Sepinwall
Publikováno v:
Neurobiology of Disease, Vol 2, Iss 2, Pp 109-118 (1995)
N-methyl-d-aspartate (NMDA) receptor antagonists have been shown to protect against focal cerebral ischaemia when administered either before or soon after the onset of ischaemia. However, the precise therapeutic window for protection using these drug
Externí odkaz:
https://doaj.org/article/6f6bca0832854a4d99ef83d8cfbb33b5
Publikováno v:
Hepatology. 37:1351-1358
A dynamic equilibrium between viral production and clearance characterizes untreated chronic hepatitis C viral infection. After initiating antiviral treatment, a typical multiphasic decay of viremia can be observed and analyzed using mathematical mod
Publikováno v:
Advanced Drug Delivery Reviews. 54:571-586
Thrice-weekly interferon alfa-2b plus ribavirin has been the standard of care for chronic hepatitis C; however, a majority of patients fail to achieve a sustained virological response with this treatment. Peginterferon alfa-2a (40 KD), interferon alf
Autor:
J. Ott, P.W. Kleyn, K. Asplund, Alberto Ponzone, Vibeke Winter, K. Das, E. Lieberman, Diana Curtis, Susan E. Hodge, Marion Mack, C. Triantaphyllidis, Niels Gregersen, G. Hallmans, Ivan Balazsc, Veronica J. Vieland, Brage S. Andresen, Patrick Willems, Stephen G. Kahler, A. Petalopoulos, S. Linn, Yuan Tsang Chen, V.A. Stepanov, S.C. Schoenbaum, Liu Mingjun, S.J. O’Brien, Jia-Huan Ding, N.P. Anagnou, N.K. Moschonas, W. Modi, T.C. Gilliam, L. Beckman, Riccardo Ponzone, L.M. Brzustowicz, Lars Bolund, J. Papamatheakis, S.V. Lemza, T.L. Munsat, Jan Hendrickx, C. Sikström, Elias O. da-Suva, David A. Greenberg, G. Beckman, M. Fousteri, H. Seuanez, L.H. Castüla, Wen Zhang, Katrine Schneiderman, Charles R. Roe, C. Mérette, G.K. Penchaszadeh, Peter Bross, A. Kouvatsi, Xin Zhenghan, Steen Kølvraa, T. Lehner, Teresa Parrella, Thomas Deufel
Publikováno v:
Human Heredity. 43:I-VI
Publikováno v:
Advances in Experimental Medicine and Biology ISBN: 0306474719
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bc0fde301a3bf4da1b31df74a43c20d8
https://doi.org/10.1007/0-306-47932-x_4
https://doi.org/10.1007/0-306-47932-x_4
Autor:
David R. Guyer, Marlene W.. Modi, Denis O'Shaughnessy, Evelyn M. Harrison, Emmett T. Cunningham, Loni da Silva
Publikováno v:
Archives of ophthalmology (Chicago, Ill. : 1960). 122(7)
Publikováno v:
Advances in experimental medicine and biology. 519
Publikováno v:
Expert opinion on investigational drugs. 10(12)
Current therapy for hepatitis C remains far from optimal. The modification of IFN by the attachment of a polyethylene glycol (PEG) moiety has produced long-lasting IFNs. A 40 kDa branched peginterferon alfa-2a (40 kDa) (PEG-IFN alfa-2a) has unique ph
Autor:
Jill E. Porter, Wolfgang Berthold, and Adrienne Farid, Carol Ann Schaffer, Pascal Bailon, Mary Graves, Marlene W. Modi, Wen Pan, Cheryl Spence, Zhi-Xin Xu, Palleroni Alicia Vallejo, George Ehrlich, Wen-Jian Fung
Publikováno v:
Bioconjugate chemistry. 12(2)
A potent, long-lasting form of interferon alpha-2a mono-pegylated with a 40 kilodalton branched poly(ethylene glycol) was designed, synthesized, and characterized. Mono-pegylated interferon alpha-2a was comprised of four major positional isomers invo
Autor:
Eva Herrmann, Avidan U. Neumann, Jung–hun Lee, Giuseppe Colucci, Stefan Zeuzem, Marlene W. Modi, Jens Fricke, W.Kurt Roth
Publikováno v:
Gastroenterology. 120(6)
Background & Aims: Covalent attachment of a 40-kilodalton polyethylene glycol moiety to interferon α2a (peginterferon α2a) results in sustained delivery and reduced clearance compared with standard interferon α2a. The aim of the study was to compa