Zobrazeno 1 - 10
of 746
pro vyhledávání: '"W, Menges"'
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 43, Iss 1, Pp 1-37 (2024)
Abstract AKT, or protein kinase B, is a central node of the PI3K signaling pathway that is pivotal for a range of normal cellular physiologies that also underlie several pathological conditions, including inflammatory and autoimmune diseases, overgro
Externí odkaz:
https://doaj.org/article/2abffedc50794523b4958f6123a95c28
Autor:
Shannon L. Wallis, Edward A. Emmett, Robyn Hardy, Brenda B. Casper, Dan J. Blanchon, Joseph R. Testa, Craig W. Menges, Cédric Gonneau, Douglas J. Jerolmack, Ali Seiphoori, Gregor Steinhorn, Terri-Ann Berry
Publikováno v:
Frontiers in Environmental Science, Vol 8 (2020)
As the 21st century uncovers ever-increasing volumes of asbestos and asbestos-contaminated waste, we need a new way to stop ‘grandfather’s problem’ from becoming that of our future generations. The production of inexpensive, mechanically strong
Externí odkaz:
https://doaj.org/article/24adaff9e96f46bfb645a0a7d90375e4
Autor:
Joseph R. Testa, Arti Shukla, Brooke T. Mossman, Mitchell Cheung, Melpo Christofidou-Solomidou, Ralph A. Pietrofesa, Andres J. Klein-Szanto, Kathy Q. Cai, Jacqueline Talarchek, Craig W. Menges, Yuwaraj Kadariya
Top, Kaplan-Meier curves depicting percent disease-free animals in asbestos-exposed Asc-/- homozygous knockout mice and similarly-exposed wild-type (WT, Asc +/+) littermates. Bottom, summary of differences in median disease-free status and MM inciden
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db794bcf97e83e6a5353833e59efc361
https://doi.org/10.1158/1940-6207.22534225.v1
https://doi.org/10.1158/1940-6207.22534225.v1
Autor:
Joseph R. Testa, Jeffrey R. Peterson, Jonathan Chernoff, Jinfei Xu, Jacqueline Talarchek, Eleonora Sementino, Craig W. Menges
PDF file - 196K, Immunoblot analysis of P-PAK1/2/3, total PAK1/2/3, P-AKT, AKT, P-ERK1/2, ERK1/2 and beta actin levels 24-hr post-nucleofection of pcDNA or pcDNA-PID in Me12 cells (left panels); pcDNA and increasing concentrations of pcDNA-PID in Mes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a83610c353ea64bd19f99066e77754d
https://doi.org/10.1158/1541-7786.22517262
https://doi.org/10.1158/1541-7786.22517262
Autor:
Joseph R. Testa, Arti Shukla, Brooke T. Mossman, Mitchell Cheung, Melpo Christofidou-Solomidou, Ralph A. Pietrofesa, Andres J. Klein-Szanto, Kathy Q. Cai, Jacqueline Talarchek, Craig W. Menges, Yuwaraj Kadariya
Conflict of Interest Form from Inflammation-Related IL1β/IL1R Signaling Promotes the Development of Asbestos-Induced Malignant Mesothelioma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d3f636251d4c0eafdf96045430ea928
https://doi.org/10.1158/1940-6207.22534228
https://doi.org/10.1158/1940-6207.22534228
Autor:
Joseph R. Testa, Jeffrey R. Peterson, Jonathan Chernoff, Jinfei Xu, Jacqueline Talarchek, Eleonora Sementino, Craig W. Menges
PDF file - 32K, IHC analysis of murine MM tissues with the P-PAK1,2,3 (Ser 141) antibody with and without pre-treatment with lambda phosphatase (lamdaPPtase)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19b892cdb5d1cd96dfeb9b7d45812762
https://doi.org/10.1158/1541-7786.22517271.v1
https://doi.org/10.1158/1541-7786.22517271.v1
Autor:
Joseph R. Testa, Jeffrey R. Peterson, Jonathan Chernoff, Jinfei Xu, Jacqueline Talarchek, Eleonora Sementino, Craig W. Menges
PDF file - 73K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ef22b5d7b5e79af224ed1574e2a1609
https://doi.org/10.1158/1541-7786.22517256.v1
https://doi.org/10.1158/1541-7786.22517256.v1
Autor:
Joseph R. Testa, Jonathan Chernoff, James S. Duncan, Suraj Peri, Kathy Q. Cai, Sofiia Karchugina, Ujjawal Shrestha, Anna-Mariya Kukuyan, Yinfei Tan, Craig W. Menges, Mitchell Cheung, Yuwaraj Kadariya, Eleonora Sementino
Supplementary Data from Inactivation of p21-Activated Kinase 2 (Pak2) Inhibits the Development of Nf2-Deficient Tumors by Restricting Downstream Hedgehog and Wnt Signaling
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04688cac9745b552483384c204e965d3
https://doi.org/10.1158/1541-7786.22527542.v1
https://doi.org/10.1158/1541-7786.22527542.v1
Autor:
Joseph R. Testa, Jeffrey R. Peterson, Jonathan Chernoff, Jinfei Xu, Jacqueline Talarchek, Eleonora Sementino, Craig W. Menges
PDF file - 27K, Expression of PID inhibits PAK phosphorylation, cell viability (MTS assay) and G418-resistant colony formation in Meso-17 cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::285450e469990e32b6a9cd400f342169
https://doi.org/10.1158/1541-7786.22517268
https://doi.org/10.1158/1541-7786.22517268
Autor:
Joseph R. Testa, Jeffrey R. Peterson, Jonathan Chernoff, Jinfei Xu, Jacqueline Talarchek, Eleonora Sementino, Craig W. Menges
PDF file - 187K, Immunoblot analysis of MM cells (Me12) treated with siRNA against PAK1 and PAK2 revealing that the slower migrating band is PAK1 and the faster migrating band is PAK2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18f1af567e9dcc8ffedfb0e64ef19663
https://doi.org/10.1158/1541-7786.22517274
https://doi.org/10.1158/1541-7786.22517274