Protective immunity of plant-produced African horse sickness virus serotype 5 chimaeric virus-like particles (VLPs) and viral protein 2 (VP2) vaccines in IFNAR -/- mice

Autor: Martha M, O'Kennedy, Peter, Coetzee, Otto, Koekemoer, Lissinda, du Plessis, Carina W, Lourens, Lusisizwe, Kwezi, Ilse, du Preez, Sipho, Mamputha, Nobalanda B, Mokoena, Daria A, Rutkowska, Jan A, Verschoor, Yolandy, Lemmer

Next generation vaccines have the capability to contribute to and revolutionise the veterinary vaccine industry. African horse sickness (AHS) is caused by an arbovirus infection and is characterised by respiratory distress and/or cardiovascular failu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5864c92681592262f8f9ec27730bc181
https://hdl.handle.net/10394/41705

Equine encephalosis in Thoroughbred foals on a South African stud farm

Autor: John D. Grewar, Peter N. Thompson, Carina W. Lourens, Alan J. Guthrie

Publikováno v: Onderstepoort Journal of Veterinary Research, Vol 82, Iss 1, Pp e1-e4 (2015)

Thoroughbred foal body temperature data were collected from shortly after birth until shortly after weaning during the 2007/2008 season on a stud farm in the Western Cape Province of South Africa. Equine encephalosis (EE) caused by EE virus (EEV) ser

Externí odkaz: https://doaj.org/article/4541aaf034334407b4d33f1437436846

Dynamics of African horse sickness virus nucleic acid and antibody in horses following immunization with a commercial polyvalent live attenuated vaccine

Autor: Christopher Joone, Carina W. Lourens, Camilla Theresa Weyer, Nigel J Maclachlan, John Duncan Grewar, Alan John Guthrie, Phillippa Burger

Publikováno v: Vaccine. 35:2504-2510

African horse sickness (AHS) is a fatal disease of equids relevant to the global equine industry. Detection of AHS virus (AHSV) during outbreaks has become more rapid and efficient with the advent of group specific reverse transcriptase quantitative

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::beb14959ac1b146f076c3c1139b2411b
https://doi.org/10.1016/j.vaccine.2017.03.005

Safety and immunogenicity of plant-produced African horse sickness virus-like particles in horses

Autor: Daria Rutkowska, Ann E. Meyers, Edward P. Rybicki, Tsepo L. Tsekoa, Inga I. Hitzeroth, Martha M. O’Kennedy, Susan J. Dennis, Carina W. Lourens

Publikováno v: Veterinary Research
Veterinary Research, BioMed Central, 2018, 49 (1), pp.105. ⟨10.1186/s13567-018-0600-4⟩
Veterinary Research, Vol 49, Iss 1, Pp 1-6 (2018)
Vet Res

African horse sickness (AHS) is caused by multiple serotypes of the dsRNA AHSV and is a major scourge of domestic equids in Africa. While there are well established commercial live attenuated vaccines produced in South Africa, risks associated with t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11515414178c9dea18a15238f7268763
https://hal.archives-ouvertes.fr/hal-02973557

Possible over-wintering of bluetongue virus in Culicoides populations in the Onderstepoort area, Gauteng, South Africa

Autor: D. Majatladi, Gert J. Venter, Solomon N.B. Boikanyo, Carina W. Lourens, Karen Ebersohn, Karien Labuschagne, Jumari Steyn, Estelle Hildegard Venter

Publikováno v: Journal of the South African Veterinary Association. 87

Several studies have demonstrated the ability of certain viruses to overwinter in arthropod vectors. The over-wintering mechanism of bluetongue virus (BTV) is unknown. One hypothesis is over-wintering within adult Culicoides midges (Diptera; Ceratopo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f302b8c3117882056b3c188dad6ec28f
https://doi.org/10.4102/jsava.v87i1.1371