Zobrazeno 1 - 10
of 631
pro vyhledávání: '"W, Lasek"'
Autor:
Jhoan S. Aguilar, Amy W. Lasek
Publikováno v:
Neurobiology of Stress, Vol 33, Iss , Pp 100692- (2024)
Perineuronal nets (PNNs) are a special form of central nervous system extracellular matrix enriched in hyaluronan, chondroitin sulfate proteoglycans, tenascins, and link proteins that regulate synaptic plasticity. Most PNNs in the brain surround parv
Externí odkaz:
https://doaj.org/article/c683666110ea4a52b4162f44d99e5bdd
Autor:
Valeria C. Torres Irizarry, Bing Feng, Xiaohua Yang, Nirali Patel, Sarah Schaul, Lucas Ibrahimi, Hui Ye, Pei Luo, Leslie Carrillo-Sáenz, Penghua Lai, Maya Kota, Devin Dixit, Chunmei Wang, Amy W. Lasek, Yanlin He, Pingwen Xu
Publikováno v:
Translational Psychiatry, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract Estrogens promote binge alcohol drinking and contribute to sex differences in alcohol use disorder. However, the mechanisms are largely unknown. This study aims to test if estrogens act on 5-hydroxytryptamine neurons in the dorsal raphe nucl
Externí odkaz:
https://doaj.org/article/87df6b4e68bc4617815407d3080e63f1
Autor:
Daniel Rafferty, Luana Martins de Carvalho, Mason Sutter, Katlyn Heneghan, Victoria Nelson, Megan Leitner, Charlotte Bolch, Amy W Lasek, Prasanth Puthanveetil
Publikováno v:
Redox Experimental Medicine, Vol 2023, Iss 1, Pp 1-16 (2023)
Binge drinking is a growing health concern among all age groups. The ability of individuals to handle ethanol in their systems differs not due to differences in enzyme expression but also due to other factors. Vital organs including brain, liver, hea
Externí odkaz:
https://doaj.org/article/51bb9b4c9cba44568f712762fce9cc61
Publikováno v:
Frontiers in Psychiatry, Vol 14 (2023)
Externí odkaz:
https://doaj.org/article/2910c0f8cf03495bb18140feaa7d76c9
Publikováno v:
Frontiers in Psychiatry, Vol 14 (2023)
Compulsive alcohol drinking is a key symptom of alcohol use disorder (AUD) that is particularly resistant to treatment. An understanding of the biological factors that underly compulsive drinking will allow for the development of new therapeutic targ
Externí odkaz:
https://doaj.org/article/3d2f468164df424abfa912a7601e0cf3
Autor:
Wei-Yang Chen, Hu Chen, Kana Hamada, Eleonora Gatta, Ying Chen, Huaibo Zhang, Jenny Drnevich, Harish R. Krishnan, Mark Maienschein-Cline, Dennis R. Grayson, Subhash C. Pandey, Amy W. Lasek
Publikováno v:
Translational Psychiatry, Vol 11, Iss 1, Pp 1-12 (2021)
Abstract Alcohol use disorder (AUD) is highly comorbid with depression. Withdrawal from chronic alcohol drinking results in depression and understanding brain molecular mechanisms that drive withdrawal-related depression is important for finding new
Externí odkaz:
https://doaj.org/article/4f01af3adbe34d83bd69eca16d8ef2c2
Publikováno v:
Frontiers in Synaptic Neuroscience, Vol 14 (2022)
Externí odkaz:
https://doaj.org/article/f3d558cddf964f12bd631c59af21789b
Autor:
Cassandre Coles, Amy W Lasek
Publikováno v:
Neuroscience Insights, Vol 16 (2021)
Alcohol use disorder is associated with pathophysiological changes in the dopaminergic system. Orthodenticle homeobox 2 (OTX2) is a transcription factor important for the development of dopaminergic neurons residing in the ventral tegmental area (VTA
Externí odkaz:
https://doaj.org/article/f9219f592092400da7bcba544ad57013
Autor:
Hu Chen, Yunlong Lu, Rui Xiong, Carlo I. Rosales, Cassandre Coles, Kana Hamada, Nuria Asad, Gregory R. J. Thatcher, Amy W. Lasek
Publikováno v:
Alcoholism: Clinical and Experimental Research. 46:1313-1320
Greater circulating levels of the steroid hormone 17β-estradiol (E2) are associated with higher levels of binge drinking in women. In female mice, estrogen receptors in the ventral tegmental area, a dopaminergic region of the brain involved in the m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::162ecd33000b600985ebe3abd2cf9c24
https://doi.org/10.1111/acer.14874
https://doi.org/10.1111/acer.14874
Publikováno v:
bioRxiv
Compulsive alcohol drinking is a key symptom of alcohol use disorder (AUD) that is particularly resistant to treatment. An understanding of the biological factors that underly compulsive drinking will allow for the development of new therapeutic targ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e01b62b7b9fe698d843a414b12d8ec29
https://doi.org/10.1101/2023.01.27.525899
https://doi.org/10.1101/2023.01.27.525899
