Zobrazeno 1 - 10
of 461
pro vyhledávání: '"W, Goodrich"'
Autor:
Shankha S. Chatterjee, Juan F. Linares, Tania Cid-Diaz, Angeles Duran, Mohd. Imran K. Khan, Marta Osrodek, Nicholas J. Brady, Miguel Reina-Campos, Antonio Marzio, Varadha Balaji Venkadakrishnan, Martin K. Bakht, Francesca Khani, Juan Miguel Mosquera, Brian D. Robinson, Jenna Moyer, Olivier Elemento, Andrew C. Hsieh, David W. Goodrich, David S. Rickman, Himisha Beltran, Jorge Moscat, Maria T. Diaz-Meco
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-23 (2024)
Abstract Overcoming resistance to therapy is a major challenge in castration-resistant prostate cancer (CRPC). Lineage plasticity towards a neuroendocrine phenotype enables CRPC to adapt and survive targeted therapies. However, the molecular mechanis
Externí odkaz:
https://doaj.org/article/db3c11d3bad84c61a1e43ee2b9c64390
Autor:
Neha Atulkumar Singh, Austin W. Goodrich, Jonathan Graff-Radford, Mary M. Machulda, Irene Sintini, Arenn F. Carlos, Carling G. Robinson, Robert I. Reid, Val J. Lowe, Clifford R. Jack, Jr, Ronald C. Petersen, Bradley F. Boeve, Keith A. Josephs, Kejal Kantarci, Jennifer L. Whitwell
Publikováno v:
NeuroImage, Vol 290, Iss , Pp 120564- (2024)
Posterior cortical atrophy (PCA) and dementia with Lewy bodies (DLB) show distinct atrophy and overlapping hypometabolism profiles, but it is unknown how disruptions in structural and functional connectivity compare between these disorders and whethe
Externí odkaz:
https://doaj.org/article/c9523c15658b48e5b201ae474cbd48e7
Autor:
George W. Goodrich, James Mark Lazenby
Publikováno v:
Nursing Open, Vol 10, Iss 3, Pp 1258-1269 (2023)
Abstract Aim To summarize the scientific literature on the elements essential to understanding a nursing definition of patient satisfaction. Design Whittemore and Knafl's methodology was used for this integrative review. Methods Articles were include
Externí odkaz:
https://doaj.org/article/9a95ff527a2b42d69551fffc3b2e13aa
Autor:
Fabio Quaglia, Shiv Ram Krishn, Khalid Sossey-Alaoui, Priyanka Shailendra Rana, Elzbieta Pluskota, Pyung Hun Park, Christopher D. Shields, Stephen Lin, Peter McCue, Andrew V. Kossenkov, Yanqing Wang, David W. Goodrich, Sheng-Yu Ku, Himisha Beltran, William K. Kelly, Eva Corey, Maja Klose, Christine Bandtlow, Qin Liu, Dario C. Altieri, Edward F. Plow, Lucia R. Languino
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-14 (2022)
Abstract Androgen deprivation therapies aimed to target prostate cancer (PrCa) are only partially successful given the occurrence of neuroendocrine PrCa (NEPrCa), a highly aggressive and highly metastatic form of PrCa, for which there is no effective
Externí odkaz:
https://doaj.org/article/3eeb18d3b89f4f6090553922e8d4285e
Autor:
Rahul Kumar, Ajay K. Chaudhary, Jordan Woytash, Joseph R. Inigo, Abhiram A. Gokhale, Wiam Bshara, Kristopher Attwood, Jianmin Wang, Joseph A. Spernyak, Eva Rath, Neelu Yadav, Dirk Haller, David W. Goodrich, Dean G. Tang, Dhyan Chandra
Publikováno v:
The Journal of Clinical Investigation, Vol 132, Iss 13 (2022)
Mitochondrial proteostasis, regulated by the mitochondrial unfolded protein response (UPRmt), is crucial for maintenance of cellular functions and survival. Elevated oxidative and proteotoxic stress in mitochondria must be attenuated by the activatio
Externí odkaz:
https://doaj.org/article/3d0a007713ee43918ce086163783b2d9
Autor:
Meenalakshmi Chinnam, Chao Xu, Rati Lama, Xiaojing Zhang, Carlos D Cedeno, Yanqing Wang, Aimee B Stablewski, David W Goodrich, Xinjiang Wang
Publikováno v:
PLoS Genetics, Vol 18, Iss 6, p e1010293 (2022)
[This corrects the article DOI: 10.1371/journal.pgen.1010171.].
Externí odkaz:
https://doaj.org/article/1982f7dc2c1c4a4fbf583248dd0a7d70
Autor:
Meenalakshmi Chinnam, Chao Xu, Rati Lama, Xiaojing Zhang, Carlos D Cedeno, Yanqing Wang, Aimee B Stablewski, David W Goodrich, Xinjiang Wang
Publikováno v:
PLoS Genetics, Vol 18, Iss 5, p e1010171 (2022)
MDM2 and MDM4 are key regulators of p53 and function as oncogenes when aberrantly expressed. MDM2 and MDM4 partner to suppress p53 transcriptional transactivation and polyubiquitinate p53 for degradation. The importance of MDM2 E3-ligase-mediated p53
Externí odkaz:
https://doaj.org/article/8f4c1404baf44626af9f2a1184976344
Autor:
Mauricio Flores, David W. Goodrich
Publikováno v:
Frontiers in Genetics, Vol 13 (2022)
The retinoblastoma susceptibility gene (RB1) is the first tumor suppressor gene discovered and a prototype for understanding regulatory networks that function in opposition to oncogenic stimuli. More than 3 decades of research has firmly established
Externí odkaz:
https://doaj.org/article/355a713c13a94562bd220fe43ab737fd
Autor:
Debra P. Ritzwoller, Glenn W. Goodrich, Heather M. Tavel, Michelle R. Odelberg, Teaniese L. Davis, Jennifer C. Gander, Courtney E. McCracken, Nancy S. Weinfield, Douglas W. Roblin
Publikováno v:
Medical Care. 61:S12-S20
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3faae848c13a06eb2f0acd4e76b5d690
https://doi.org/10.1097/mlr.0000000000001792
https://doi.org/10.1097/mlr.0000000000001792
Autor:
Fabio Quaglia, Shiv Ram Krishn, Yanqing Wang, David W Goodrich, Peter McCue, Andrew V Kossenkov, Amy C Mandigo, Karen E Knudsen, Paul H Weinreb, Eva Corey, William K Kelly, Lucia R Languino
Publikováno v:
PLoS ONE, Vol 16, Iss 1, p e0244985 (2021)
Neuroendocrine prostate cancer (NEPrCa) arises de novo or after accumulation of genomic alterations in pre-existing adenocarcinoma tumors in response to androgen deprivation therapies. We have provided evidence that small extracellular vesicles relea
Externí odkaz:
https://doaj.org/article/976a661517ad44058853982bade5a864