Zobrazeno 1 - 10
of 849
pro vyhledávání: '"W, Göbel"'
Autor:
Mohammad A. Sabsabi, Ahmed Kheimar, Yu You, Dominik von La Roche, Sonja Härtle, Thomas W. Göbel, Theresa von Heyl, Benjamin Schusser, Benedikt B. Kaufer
Publikováno v:
mBio, Vol 15, Iss 8 (2024)
ABSTRACT Marek’s disease virus (MDV) is an oncogenic alphaherpesvirus that causes deadly lymphomas in chickens. In chickens, up to 50% of all peripheral T cells are gamma delta (γδ) T cells. Until now, their role in MDV pathogenesis and tumor for
Externí odkaz:
https://doaj.org/article/0c96e4576b904e06a16d362eecd77b83
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
T cell receptor (TCR) repertoire sequencing has emerged as a powerful tool for understanding the diversity and functionality of T cells within the host immune system. Yet, the chicken TCR repertoire remains poorly understood due to incomplete genome
Externí odkaz:
https://doaj.org/article/20fe5ed6d96c48a8af86d05b829b1605
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
In chickens, γδ T cells represent a large fraction of peripheral T cells; however, their function remains largely unknown. Here, we describe the selective in vitro expansion of γδ T cells from total splenocytes by stimulation with the cytokines I
Externí odkaz:
https://doaj.org/article/cf1a7ddf1c7b49f2a76e4a20fd12d32f
Publikováno v:
Beilstein Journal of Organic Chemistry, Vol 14, Iss 1, Pp 1563-1569 (2018)
TEMPO spin labels protected with 2-nitrobenzyloxymethyl groups were attached to the amino residues of three different nucleosides: deoxycytidine, deoxyadenosine, and adenosine. The corresponding phosphoramidites could be incorporated by unmodified st
Externí odkaz:
https://doaj.org/article/455c1588d27644cfac493d56c4b31a86
Autor:
Yu You, Tereza Vychodil, Giulia Aimola, Renato L. Previdelli, Thomas W. Göbel, Luca D. Bertzbach, Benedikt B. Kaufer
Publikováno v:
Microorganisms, Vol 9, Iss 12, p 2489 (2021)
Marek’s disease virus (MDV) is a highly oncogenic alphaherpesvirus that causes a devastating neoplastic disease in chickens. MDV has been shown to integrate its genome into the telomeres of latently infected and tumor cells, which is crucial for ef
Externí odkaz:
https://doaj.org/article/ed3e3bf2fd3c4edf92ec5935539e52ca
Autor:
El Kahina Meziane, Nicola D. Potts, Birgit C. Viertlboeck, Hanne Løvlie, Andrew P. Krupa, Terry A. Burke, Stewart Brown, Kellie A. Watson, David S. Richardson, Tommaso Pizzari, Thomas W. Göbel, Jim Kaufman
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
The leukocyte receptor complex (LRC) in humans encodes many receptors with immunoglobulin-like (Ig-like) extracellular domains, including the killer Ig-like receptors (KIRs) expressed on natural killer (NK) cells among others, the leukocyte Ig-like r
Externí odkaz:
https://doaj.org/article/8c5cea1db9244be98466e26205d12178
Akademický článek
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Publikováno v:
Beilstein Journal of Organic Chemistry, Vol 12, Iss 1, Pp 1870-1876 (2016)
Starting from (S)-β-phenylalanine, easily accessible by lipase-catalyzed kinetic resolution, a chiral triamine was assembled by a reductive amination and finally cyclized to form the title compound 10. In the crystals of the guanidinium benzoate sal
Externí odkaz:
https://doaj.org/article/7b139e7f13234738bb612bc0f345f7ae
Publikováno v:
Arkivoc. 2021:225-238
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::06f33b7e4d40694fea964607da2c2c2d
https://doi.org/10.24820/ark.5550190.p011.722
https://doi.org/10.24820/ark.5550190.p011.722
Autor:
Felix Zellmann, Michael W. Göbel
Publikováno v:
Molecules, Vol 25, Iss 8, p 1842 (2020)
The RNA cleaving catalyst tris(2-aminobenzimidazole) when attached to the 5’ terminus of oligonucleotides cuts complementary RNA strands in a highly site-specific manner. Conjugation was previously achieved by the acylation of an amino linker by an
Externí odkaz:
https://doaj.org/article/772be71e4a6b4f358f25fd67ad0e65c9