Zobrazeno 1 - 10
of 394
pro vyhledávání: '"W, Fürst"'
Autor:
James W. Fuerst
The first full-length study to treat both parts of Inca Garcilaso de la Vega's foundational text Royal Commentaries of the Incas as a seminal work of political thought in the formation of the early Americas and the early-modern period. It is also amo
Autor:
Isabelle Serr, Rainer W. Fürst, Peter Achenbach, Martin G. Scherm, Füsun Gökmen, Florian Haupt, Eva-Maria Sedlmeier, Annette Knopff, Leonard Shultz, Richard A. Willis, Anette-Gabriele Ziegler, Carolin Daniel
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-18 (2016)
Type 1 diabetes is associated with the loss of self-tolerance to the insulin-producing β-cells in the pancreas. Here the authors show that vaccination with insulin mimetopes can induce human insulin-specific regulatory T cells to mediate tolerance i
Externí odkaz:
https://doaj.org/article/384e9f53afaf4353a75ebc119a70470f
Autor:
Christoph Dahlhoff, Charles Desmarchelier, Manuela Sailer, Rainer W Fürst, Alexander Haag, Susanne E Ulbrich, Björn Hummel, Rima Obeid, Jürgen Geisel, Bernhard L Bader, Hannelore Daniel
Publikováno v:
PLoS ONE, Vol 8, Iss 3, p e57387 (2013)
Obesity is an underlying risk factor in the development of cardiovascular disease, dyslipidemia and non-alcoholic fatty liver disease (NAFLD). Increased hepatic lipid accumulation is a hallmark in the progression of NAFLD and impairments in liver pho
Externí odkaz:
https://doaj.org/article/b1bdba7ee80a47a8aecdb10c3b4e2918
Autor:
Christoph Dahlhoff, Charles Desmarchelier, Manuela Sailer, Rainer W. Fürst, Alexander Haag, Susanne E. Ulbrich, Björn Hummel, Rima Obeid, Jürgen Geisel, Bernhard L. Bader, Hannelore Daniel
Publikováno v:
PLoS ONE, Vol 8, Iss 10 (2013)
Externí odkaz:
https://doaj.org/article/db1c649d3faf4f3dba0edff71614d04d
Autor:
Daniela Bebbere, Stefan Bauersachs, Rainer W Fürst, Horst-Dieter Reichenbach, Myriam Reichenbach, Ivica Medugorac, Susanne E Ulbrich, Eckhard Wolf, Sergio Ledda, Stefan Hiendleder
Publikováno v:
PLoS ONE, Vol 8, Iss 4, p e59564 (2013)
The insulin-like growth factor 2 receptor (IGF2R) is essential for prenatal growth regulation and shows gene dosage effects on fetal weight that can be affected by in-vitro embryo culture. Imprinted maternal expression of murine Igf2r is well documen
Externí odkaz:
https://doaj.org/article/1fb05fd787f74f348aa9279004716efb
Autor:
Veronika L. Flöter, M. Reichenbach, Helmut Blum, Susanne E. Ulbrich, Stefan Krebs, Stefan Bauersachs, Rainer W. Fürst
Publikováno v:
Biology of Reproduction, 100 (3)
Maternal exposure to estrogens can induce long-term adverse effects in the offspring. The epigenetic programming may start as early as the period of preimplantation development. We analyzed the effects of gestational estradiol-17β (E2) exposure with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eaa6ea5d1276c8824c39617e54d64ca1
https://hdl.handle.net/20.500.11850/335968
https://hdl.handle.net/20.500.11850/335968
Autor:
Thomas B. Hildebrandt, Wolfgang Wuttke, Gabriela Galateanu, Erich Möstl, Susanne E. Ulbrich, Veronika L. Flöter, Dana Seidlova-Wuttke, Rainer W. Fürst
Publikováno v:
Toxicology. :60-67
Estrogens are important for the bone development and health. Exposure to endocrine disrupting chemicals during the early development has been shown to affect the bone phenotype later in life. Several studies have been performed in rodents, while in l
Autor:
Leonard Shultz, Anette Gabriele Ziegler, Carolin Daniel, Isabelle Serr, Peter Achenbach, F Haupt, A. Knopff, Martin G. Scherm, Eva Maria Sedlmeier, Füsun Gökmen, Richard A. Willis, Rainer W. Fürst
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-18 (2016)
Nature Communications
Nat. Commun. 7:10991 (2016)
Nature Communications
Nat. Commun. 7:10991 (2016)
Immune tolerance is executed partly by Foxp3+regulatory T (Treg) cells, which suppress autoreactive T cells. In autoimmune type 1 diabetes (T1D) impaired tolerance promotes destruction of insulin-producing β-cells. The development of autoantigen-spe
Autor:
Benedikt Kirchner, Carolin Daniel, Stefanie Kälin, Isabelle Serr, Nicole Kunschke, Michael W. Pfaffl, Anette-G. Ziegler, Ari Waisman, Martin G. Scherm, Stephanie Zillmer, Benno Weigmann, Richard A. Willis, Füsun Gökmen, Alexei Nikolaev, Melanie Bunk, Bettina Haase, Brigitta Loretz, Rainer W. Fürst, Verena B. Ott, Claus-Michael Lehr
Publikováno v:
Proc. Natl. Acad. Sci. U.S.A. 113, E6659-E6668 (2016)
Aberrant immune activation mediated by T effector cell populations is pivotal in the onset of autoimmunity in type 1 diabetes (T1D). T follicular helper (TFH) cells are essential in the induction of high-affinity antibodies, and their precursor memor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1071161a2d4df581ad5b35fc59dc9183
https://hdl.handle.net/10033/621272
https://hdl.handle.net/10033/621272
Publikováno v:
Molecular and Cellular Endocrinology. 348:67-77
Epigenetic events controlling the transcriptional regulation of genes involved in endometrial function during the estrous cycle and early pregnancy have only sparsely been investigated. We analyzed the gene expression of DNA methyltransferases and th