Zobrazeno 1 - 10 of 799 pro vyhledávání: '"W, Erhardt"'
1
Akademický článek
The JNK signaling pathway plays a key role in methuosis (non-apoptotic cell death) induced by MOMIPP in glioblastoma
Autor: Zehui Li, Nneka E. Mbah, Jean H. Overmeyer, Jeffrey G. Sarver, Sage George, Christopher J. Trabbic, Paul W. Erhardt, William A. Maltese
Publikováno v: BMC Cancer, Vol 19, Iss 1, Pp 1-20 (2019)
Abstract Background Synthetic indolyl- pyridinyl- propenones (IPPs) induce methuosis, a form of non-apoptotic cell death, in glioblastoma and other cancer cell lines. Methuosis is characterized by accumulation of cytoplasmic vacuoles derived from mac
Externí odkaz: https://doaj.org/article/eae6fa1817ca47178f7cde468fe5291f
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2
Akademický článek
Leukocyte integrin Mac-1 regulates thrombosis via interaction with platelet GPIbα
Autor: Yunmei Wang, Huiyun Gao, Can Shi, Paul W. Erhardt, Alexander Pavlovsky, Dmitry A. Soloviev, Kamila Bledzka, Valentin Ustinov, Liang Zhu, Jun Qin, Adam D. Munday, Jose Lopez, Edward Plow, Daniel I. Simon
Publikováno v: Nature Communications, Vol 8, Iss 1, Pp 1-16 (2017)
The binding of the leukocyte integrin Mac1 to the platelet receptor GPIbα is important for the physiological response to tissue injury. Here the authors show that this interaction also regulates thrombosis, without influencing bleeding time, which m
Externí odkaz: https://doaj.org/article/fde7eceb216348f28d8514ea1e616f3d
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3
Akademický článek
Cytochrome P450, CYP93A1, as defense marker in soybean
Autor: A. J. Kinzler, Z. A. Prokopiak, M. M. Vaughan, P. W. Erhardt, J. G. Sarver, J. A. Trendel, Z. Zhang, N. J. Dafoe
Publikováno v: Biologia Plantarum, Vol 60, Iss 4, Pp 724-730 (2016)
Cytochrome P450, CYP93A1, is involved in the synthesis of the phytoalexin glyceollin in soybean (Glycine max L. Merr). The gene encoding CYP93A1 has been used as defense marker in soybean cell cultures, however, little is known regarding how this gen
Externí odkaz: https://doaj.org/article/cf2c04d3037f47ffad30d653bee451dc
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7
The JNK signaling pathway plays a key role in methuosis (non-apoptotic cell death) induced by MOMIPP in glioblastoma
Autor: Paul W. Erhardt, Zehui Li, Sage George, Nneka E. Mbah, Jean H. Overmeyer, William A. Maltese, Christopher J. Trabbic, Jeffrey G. Sarver
Publikováno v: BMC Cancer, Vol 19, Iss 1, Pp 1-20 (2019)
BMC Cancer
Background Synthetic indolyl- pyridinyl- propenones (IPPs) induce methuosis, a form of non-apoptotic cell death, in glioblastoma and other cancer cell lines. Methuosis is characterized by accumulation of cytoplasmic vacuoles derived from macropinosom
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12fa7732e9cf1e04512a719b4b44d90e
http://link.springer.com/article/10.1186/s12885-019-5288-y
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8
Akademický článek
Correction: Corrigendum: Leukocyte integrin Mac-1 regulates thrombosis via interaction with platelet GPIbα
Autor: Yunmei Wang, Huiyun Gao, Can Shi, Paul W. Erhardt, Alexander Pavlovsky, Dmitry A. Soloviev, Kamila Bledzka, Valentin Ustinov, Liang Zhu, Jun Qin, Adam D. Munday, Jose Lopez, Edward Plow, Daniel I. Simon
Publikováno v: Nature Communications, Vol 8, Iss 1, Pp 1-1 (2017)
Nature Communications 8: Article number:15559 (2017); Published 30 May 2017; Updated 4 July 2017 The original version of this Article contained an error in the email address of the corresponding author Daniel I. Simon. The correct email is Daniel.Sim
Externí odkaz: https://doaj.org/article/aec6ecbcaca9430582897409a185d07d
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9
Synthesis and Evaluation of PPARδ Agonists That Promote Osteogenesis in a Human Mesenchymal Stem Cell Culture and in a Mouse Model of Human Osteoporosis
Autor: Jared R Mayo, Donghyun Kim, Jill A. Trendel, Divya Andy, Paul W. Erhardt, Benjamin Heck, Jeffery T Farris, Jeffrey G. Sarver, Brian Kress, Bruce E. Heck
Publikováno v: Journal of medicinal chemistry. 64(10)
We synthesized a directed library of compounds to explore the structure-activity relationships of peroxisome proliferator-activated receptor δ (PPARδ) activation relative to mesenchymal stem cell (MSC) osteogenesis. Our scaffold used para-substitut
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f2dba4d6b285c6cb4d8fc982fa855c5
https://pubmed.ncbi.nlm.nih.gov/33988379
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10
Glossary and tutorial of xenobiotic metabolism terms used during small molecule drug discovery and development (IUPAC Technical Report)
Autor: Raymond F. Novak, Brian Kress, G. Gordon Gibson, Michael Boberg, Jeffrey G. Sarver, Nico P. E. Vermeulen, Steven A. Wrighton, Phillip S. Portoghese, Nicholas Bodor, Kenneth Bachmann, Jack Hinson, Amarjit Luniwal, M. Teresa Serafini, Donald J. Birkett, Daniel Koehler, David R. Hawkins, Hiroshi Masumoto, Paul W. Erhardt, Gabrielle Hawksworth, Christopher J. Trabbic
Publikováno v: Erhardt, P, Bachmann, K, Birkett, D, Boberg, M, Bodor, N, Gibson, G, Hawkins, D, Hawksworth, G, Hinson, J, Koehler, D, Kress, B, Luniwal, A, Masumoto, H, Novak, R, Portoghese, P, Sarver, J, Serafini, M T, Trabbic, C, Vermeulen, N & Wrighton, S 2021, ' Glossary and tutorial of xenobiotic metabolism terms used during small molecule drug discovery and development (IUPAC Technical Report) ', Pure and Applied Chemistry, vol. 93, no. 3, pp. 273-403 . https://doi.org/10.1515/pac-2018-0208
Pure and Applied Chemistry, 93(3), 273-403. IUPAC Secretariat
© 2021 IUPAC & De Gruyter. This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. For more information, please visit: http://creativecommons.org/licenses/by-nc-nd/4.0/ 2021.This project orig
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f8509c6fdda44736f10a565af150c11
https://research.vu.nl/en/publications/3219fb5d-9fad-4fb4-bd54-21dbe7ffe060
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