Zobrazeno 1 - 10
of 81
pro vyhledávání: '"W, Englberger"'
Autor:
Thomas Christoph, U. Jahnel, De Vry J, B.Y. Kögel, Thomas M. Tzschentke, Wolfgang P. Schröder, W. Englberger
Publikováno v:
Der Schmerz. 25:19-25
Tapentadol (3-[(1R, 2R)-3-(dimethylamino)-1-ethyl-2-methylpropyl] phenol) is a centrally acting analgesic of a new substance class for the treatment of severe nociceptive and neuropathic pain. Tapentadol combines μ-opioid receptor (MOR) agonism and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bc37f1c4c9f6e7f7fa8bc25f379f1466
https://doi.org/10.1007/s00482-010-1004-1
https://doi.org/10.1007/s00482-010-1004-1
Autor:
Wolfgang Brandt, Elmar Friderichs, Wolfgang Strasburger, Michael Haurand, T. Siener, Babette-Yvonne Kögel, Ulrike Holzgrabe, W. Englberger, Antonella Cambareri, Ulrich Kuhl
Publikováno v:
Il Farmaco. 57:531-534
The 1,5-dimethyl 3,7-diaza-3,7-dimethyl-9-oxo-2,4-di-2-pyridine-bicyclo[3.3.1]nonane-1,5-dicarboxylate, HZ2, has a high and selective affinity for the kappa opioid receptor and an antinociceptive activity comparable to morphine. In addition, it is ch
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4fe0b6c1cf5f384c015113efdc792cd8
https://doi.org/10.1016/s0014-827x(02)01243-0
https://doi.org/10.1016/s0014-827x(02)01243-0
Publikováno v:
Methods and findings in experimental and clinical pharmacology. 32(1)
Tapentadol is a novel, centrally acting analgesic combining micro-opioid receptor (MOR) agonism and noradrenaline (NA) reuptake inhibition in a single molecule. Many classic opioids form active metabolites that contribute to analgesia and/or side eff
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82d031e3d276c15bb90ad2027b5722e7
https://pubmed.ncbi.nlm.nih.gov/20383344
https://pubmed.ncbi.nlm.nih.gov/20383344
Publikováno v:
Arzneimittel-Forschung. 46(11)
In in vitro receptor binding and synaptosomal uptake experiments the (+)-enantiomer of tramadol (CAS 148229-78-1) is specific for the mu-opioid receptor site and for the serotonin (5-HT) carrier, whereas the (-)-enantiomer (CAS 148229-79-2) has a hig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::60d997a19680cc62100b4d33aefb322e
https://pubmed.ncbi.nlm.nih.gov/8955860
https://pubmed.ncbi.nlm.nih.gov/8955860
Autor:
Thomas Christoph, W. Englberger, K. Schiene, Rolf Terlinden, Wolfgang Schröder, Thomas M. Tzschentke, B.Y. Kögel, J. De Vry
Publikováno v:
European Journal of Pain Supplements. 5:114-114
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c3416147ac31e592f2b570ccf2fef585
https://doi.org/10.1016/s1754-3207(11)70389-3
https://doi.org/10.1016/s1754-3207(11)70389-3
Autor:
Thomas Christoph, Babette-Yvonne Kögel, J. De Vry, T.I.F.H. Cremers, W. Englberger, Thomas M. Tzschentke, G. Bahrenberg, K. Schiene
Publikováno v:
The Journal of Pain. 9:31
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ff8d12bf31445f1b818c72a2900d11c2
https://doi.org/10.1016/j.jpain.2008.01.144
https://doi.org/10.1016/j.jpain.2008.01.144
Autor:
T.I.F.H. Cremers, U. Jahnel, Babette-Yvonne Kögel, W. Englberger, J. Vry, Thomas M. Tzschentke, Thomas Christoph, H. H. Hennies, Elmar Friderichs, Klaus Schiene
Publikováno v:
European Journal of Pain. 10:S54-S54
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a011d148ae946bc8050d48e94e80d884
https://doi.org/10.1016/s1090-3801(06)60199-7
https://doi.org/10.1016/s1090-3801(06)60199-7
Autor:
U. Jahnel, Thomas M. Tzschentke, Thomas I. F. H. Cremers, Hagen-Heinrich Hennies, Thomas Christoph, B. Koegel, W. Englberger, J. De Vry
Publikováno v:
The Journal of Pain. 7:S25
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1691892648052f62db99a47992e85e03
https://doi.org/10.1016/j.jpain.2006.01.088
https://doi.org/10.1016/j.jpain.2006.01.088
Publikováno v:
International Journal of Immunopharmacology. 9:275-282
Lysophosphatidylcholine (LC), platelet activating factor (PAF) and its precursor lysophosphatidalcholine (LP) enhance O-2-release by polymorphonuclear leucocytes (PMNL) triggered by PMA whereas lysophospholipids with other polar headgroups fail to do
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::983c375ad05d398f6b981dbd6465f4f0
https://doi.org/10.1016/0192-0561(87)90051-8
https://doi.org/10.1016/0192-0561(87)90051-8
Publikováno v:
Molecular Pharmacology; August 1999, Vol. 56 Issue: 2 p334-8, 5p