Zobrazeno 1 - 10
of 1 191
pro vyhledávání: '"W, Brunner"'
Publikováno v:
Neurobiology of Disease, Vol 204, Iss , Pp 106759- (2025)
Mutations in the microtubule-binding motor protein kinesin 5 A (KIF5A) are implicated in several adult-onset motor neuron diseases, including Amyotrophic Lateral Sclerosis, Spastic Paraplegia Type 10 and Charcot-Marie-Tooth Disease Type 2. While KIF5
Externí odkaz:
https://doaj.org/article/eca09670f2be4868b2736385fe27ea62
Autor:
Marieke Meijer, Kristina Rehbach, Jessie W. Brunner, Jessica A. Classen, Hanna C.A. Lammertse, Lola A. van Linge, Desiree Schut, Tamara Krutenko, Matthias Hebisch, L. Niels Cornelisse, Patrick F. Sullivan, Michael Peitz, Ruud F. Toonen, Oliver Brüstle, Matthijs Verhage
Publikováno v:
Cell Reports, Vol 27, Iss 7, Pp 2199-2211.e6 (2019)
Summary: Synaptic dysfunction is associated with many brain disorders, but robust human cell models to study synaptic transmission and plasticity are lacking. Instead, current in vitro studies on human neurons typically rely on spontaneous synaptic e
Externí odkaz:
https://doaj.org/article/20c05e78a6744a9bb42bc89f2c5fbe99
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Autor:
Jason Weatherald, Mitesh V. Thakrar, Rhea A. Varughese, Mithum Kularatne, Jonathan Liu, Lea Harper, Omid Kiamanesh, Nowell Fine, Evan Orlikow, Chidera Nwaroh, Christina Thornton, John Swiston, Lisa Kolkman, Nathan W. Brunner, Doug Helmersen, Naushad Hirani
Publikováno v:
The Journal of Heart and Lung Transplantation. 41:563-567
Initial combination therapy with an endothelin receptor antagonist (ERA) and riociguat in pulmonary arterial hypertension (PAH) has limited supporting data.We performed a prospective, single-arm, open-label trial of riociguat, and ambrisentan for inc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2ef12b65e28c04b3e8cccd0d082ea11
https://doi.org/10.1016/j.healun.2022.01.002
https://doi.org/10.1016/j.healun.2022.01.002
Autor:
Nima Moghaddam, John R. Swiston, Robert D. Levy, Lisa Lee, Victor F. Huckell, Nathan W. Brunner
Publikováno v:
Pulmonary Circulation, Vol 9 (2018)
Fluid challenge during right heart catheterization has been used for unmasking pulmonary hypertension (PH) related to left-sided heart disease. We evaluated the clinical and hemodynamic factors affecting the response to fluid challenge and investigat
Externí odkaz:
https://doaj.org/article/d8340c119f5b4ab29ac5acacce540784
Publikováno v:
Pulmonary Circulation, Vol 8 (2018)
Pulmonary artery (PA) vasculitis occurs in association with primary vasculitides—in particular, giant cell arteritis, Takayasu’s arteritis, or Behçet’s disease—or secondary vasculitis as a result of infections or malignancy. However, PA vasc
Externí odkaz:
https://doaj.org/article/23caabbee9e24543b5dd63b6fb56abe8
Autor:
Manuel J. Richter, Federico Fortuni, Fawaz Alenezi, Michele D'Alto, Roberto Badagliacca, Nathan W. Brunner, Arie P. van Dijk, Philipp Douschan, Henning Gall, Stefano Ghio, Francesco Lo Giudice, Ekkehard Grünig, Francois Haddad, Luke Howard, Sudarshan Rajagopal, Niels Stens, Davide Stolfo, Dick H.J. Thijssen, Carmine Dario Vizza, Roham T. Zamanian, Liang Zhong, Werner Seeger, Hossein A. Ghofrani, Khodr Tello
Publikováno v:
Journal of Heart and Lung Transplantation, 42, 433-446
Journal of Heart and Lung Transplantation, 42, 4, pp. 433-446
Journal of Heart and Lung Transplantation, 42, 4, pp. 433-446
Contains fulltext : 291541.pdf (Publisher’s version ) (Closed access) BACKGROUND: Right atrial (RA) imaging has emerged as a promising tool for the evaluation of patients with pulmonary hypertension (PH), albeit without systematic validation. METHO
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f057b0cb4b6e4bc89eaeeb4745799147
http://hdl.handle.net/2066/291541
http://hdl.handle.net/2066/291541
Autor:
Eric C. Leung, John R. Swiston, Leena AlAhmari, Tasneem AlAhmari, Victor F. Huckell, Nathan W. Brunner
Publikováno v:
Pulmonary Circulation, Vol 8 (2017)
The determination of LV filling pressure is integral to the diagnosis of pulmonary arterial hypertension (PAH). The American Society of Echocardiography (ASE) has devised algorithms for their estimation. We aimed to test these algorithms in a populat
Externí odkaz:
https://doaj.org/article/1c2430e4fe134455bec1a0a6ade01806
Autor:
Akshay Bagai, Shaun G. Goodman, Hahn Hoe Kim, Andrew T. Yan, Andrea Lavoie, Christopher B. Fordyce, Ashish Patel, Nathan W. Brunner, Tara Sedlak, Sean Jedrzkiewicz, Saleem Kassam, Roger K. Philipp, Sohrab Lutchmedial, Shahar Lavi, Mina Madan, Thao Huynh, Sam Radhakrishnan, Michael Heffernan, Andrew L Mathew, Mary Tan, Jean-Pierre Déry, Payam Dehghani, Robert McKelvie, Neville Suskin, Colin Barry, Tomas Cieza, Razi Khan, Shaheeda Ahmed
Publikováno v:
Clinical Cardiology. 44:839-847
BACKGROUND After myocardial infarction, guidelines recommend higher-potency P2Y12 receptor inhibitors, namely ticagrelor and prasugrel, over clopidogrel. HYPOTHESIS We aimed to determine the contemporary use of higher-potency antiplatelet therapy in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::77ac8ee0137767bbe7b0c5f161b437e8
https://doi.org/10.1002/clc.23618
https://doi.org/10.1002/clc.23618