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of 870
pro vyhledávání: '"W, Brumfitt"'
Publikováno v:
Liver. 3:201-206
The biliary excretion and pharmacokinetics of mezlocillin have been studied in jaundiced patients with total external bile drainage through a percutaneous transhepatic catheter. In 10 of 11 studies, 2 g mezlocillin intravenously resulted in biliary c
Autor:
W. Brumfitt, J.M.T. Hamilton-Miller
Publikováno v:
Journal of Chemotherapy. 11:163-178
We review the discovery and development of the cephalosporins and subsequently cefaclor. Cefaclor is active against a wide range of commonly encountered bacterial pathogens, acting by inhibiting cell wall synthesis. Its in vitro activity compares fav
Autor:
W. Brumfitt
If the organizers of the excellent symposium, on which this book is based, had wanted to devise an appropriate dramatic opening they could not have done better than to have the first speaker fail to appear because he was incarcerated in his high secu
Autor:
J. M. T. Hamilton-Miller, W. Brumfitt
Publikováno v:
Journal of Antimicrobial Chemotherapy. 33:147-153
Twenty-four general practitioners completed a questionnaire on behalf of their partners in the practices before attending the symposium. The main points that emerged were that trimethoprim was the most popular antibiotic for treatment of acute urinar
Autor:
W. Brumfitt, J. M. T. Hamilton-Miller
Publikováno v:
Journal of Chemotherapy. 5:465-469
Trimethoprim is the best known inhibitor of bacterial dihydrofolate reductase. Initially, this was always combined with sulphamethoxazole. It was later combined with other sulphonamides (eg. sulphamoxole, sulphadiazine or sulfametopyrazine), but the
Publikováno v:
Journal of Medical Microbiology. 39:69-73
Experiments were performed to determine the effects of products of bacterial growth (including endotoxin) on phagocytosis and intracellular killing by polymorphonuclear leucocytes (PMNL) in urine. Bacteriologically filtered supernates of two strains
Publikováno v:
European Journal of Clinical Microbiology & Infectious Diseases. 12:534-539
The effect of alkalinisation and increased fluid intake on bacterial phagocytosis and killing in urine was studied. Phagocytosis of Escherichia coli and Staphylococcus saprophyticus by polymorphonuclear neutrophils (PMN) took place in only one of thr
Publikováno v:
Journal of Hepatology. 17:408-414
Primary biliary cirrhosis (PBC) patients have a higher incidence of recurrent urinary tract infection and an increased prevalence of rough forms (mutants) of E. coli in their stool samples than other chronic liver disease patients. PBC patients exhib
Autor:
J. M. T. Hamilton-Miller, W. Brumfitt
Publikováno v:
Diagnostic Microbiology and Infectious Disease. 15:621-625
The oxazolidinone compound E3709, which contains a 4-pyridyl group, was found to be more active in vitro than other members of this series, such as DuP 721. MIC 90 for staphylococci (including methicillin-resistant isolates), streptococci (including