Zobrazeno 1 - 10
of 1 150
pro vyhledávání: '"W, Bock"'
Autor:
Mallory L. Myers, John R. Gallagher, Alexander J. Kim, Walker H. Payne, Samantha Maldonado-Puga, Haralabos Assimakopoulos, Kevin W. Bock, Udana Torian, Ian N. Moore, Audray K. Harris
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)
Here, Myers and Gallagher et al. characterize the structural organization of commercial influenza vaccines. The vaccines differ in their structural composition and identify a “spiked nanodisc” arrangement of hemagglutinin (HA) with increased disp
Externí odkaz:
https://doaj.org/article/ba1072ef111547a587d63a9bc981960e
Autor:
Dapeng Li, David R. Martinez, Alexandra Schäfer, Haiyan Chen, Maggie Barr, Laura L. Sutherland, Esther Lee, Robert Parks, Dieter Mielke, Whitney Edwards, Amanda Newman, Kevin W. Bock, Mahnaz Minai, Bianca M. Nagata, Matthew Gagne, Daniel C. Douek, C. Todd DeMarco, Thomas N. Denny, Thomas H. Oguin, Alecia Brown, Wes Rountree, Yunfei Wang, Katayoun Mansouri, Robert J. Edwards, Guido Ferrari, Gregory D. Sempowski, Amanda Eaton, Juanjie Tang, Derek W. Cain, Sampa Santra, Norbert Pardi, Drew Weissman, Mark A. Tomai, Christopher B. Fox, Ian N. Moore, Hanne Andersen, Mark G. Lewis, Hana Golding, Robert Seder, Surender Khurana, Ralph S. Baric, David C. Montefiori, Kevin O. Saunders, Barton F. Haynes
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-15 (2022)
The authors have previously demonstrated the neutralising capacity of their nanoparticle vaccine, as well as showing protection of non-human primates from SARS-CoV-2 WA-1 infection. In this work, they investigate the ability of their vaccine candidat
Externí odkaz:
https://doaj.org/article/b08586c46f7c4fa6b00bfd070a9caed1
Autor:
Mallory L. Myers, John R. Gallagher, De’Marcus D. Woolfork, Regan K. Stradtmann-Carvalho, Samantha Maldonado-Puga, Kevin W. Bock, Seyhan Boyoglu-Barnum, Hubza Syeda, Adrian Creanga, Derron A. Alves, Masaru Kanekiyo, Audray K. Harris
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Externí odkaz:
https://doaj.org/article/bb7b3f7edfea42d98380f173f65a6023
Autor:
Chunfu Yang, Lei Lei, John W. Marshall Collins, Michael Briones, Li Ma, Gail L. Sturdevant, Hua Su, Anuj K. Kashyap, David Dorward, Kevin W. Bock, Ian N. Moore, Christine Bonner, Chih-Yu Chen, Craig A. Martens, Stacy Ricklefs, Masahiro Yamamoto, Kiyoshi Takeda, Yoichiro Iwakura, Grant McClarty, Harlan D. Caldwell
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
Myeloid cells are implicated in the innate immune and inflammatory response during infection with Chlamydia trachomatis. Here the authors show the evasion of the neutrophil response to infection and concomitant induction of sterile immunity via the p
Externí odkaz:
https://doaj.org/article/9b6d6afc6d5a40fdb29b81834b7b8934
Autor:
Mallory L. Myers, John R. Gallagher, De’Marcus D. Woolfork, Regan K. Stradtmann-Carvalho, Samantha Maldonado-Puga, Kevin W. Bock, Seyhan Boyoglu-Barnum, Hubza Syeda, Adrian Creanga, Derron A. Alves, Masaru Kanekiyo, Audray K. Harris
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
As new vaccine technologies and platforms, such as nanoparticles and novel adjuvants, are developed to aid in the establishment of a universal influenza vaccine, studying traditional influenza split/subunit vaccines should not be overlooked. Commerci
Externí odkaz:
https://doaj.org/article/12a8ae4464884095aa89e2048a346218
Publikováno v:
Frontiers in Psychiatry, Vol 12 (2021)
Objective: To examine the nature and scope of questions about psychiatric patient cases submitted by general practitioners (GPs) to an established online consultation platform and to determine if they could have been answered by consulting existing c
Externí odkaz:
https://doaj.org/article/edc2409f9b3144788e68946bcc8b3523
Autor:
Yongjun Sui, Jianping Li, Roushu Zhang, Sunaina Kiran Prabhu, Hanne Andersen, David Venzon, Anthony Cook, Renita Brown, Elyse Teow, Jason Velasco, Jack Greenhouse, Tammy Putman-Taylor, Tracey-Ann Campbell, Laurent Pessaint, Ian N. Moore, Laurel Lagenaur, Jim Talton, Matthew W. Breed, Josh Kramer, Kevin W. Bock, Mahnaz Minai, Bianca M. Nagata, Mark G. Lewis, Lai-Xi Wang, Jay A. Berzofsky
Publikováno v:
JCI Insight, Vol 6, Iss 10 (2021)
Effective SARS-CoV-2 vaccines are urgently needed. Although most vaccine strategies have focused on systemic immunization, here we compared the protective efficacy of 2 adjuvanted subunit vaccines with spike protein S1: an intramuscularly primed/boos
Externí odkaz:
https://doaj.org/article/d56cb415c28b4c54afc3a16c9c73cf2f
Autor:
Zhaochun Chen, Ronald E Engle, Chen-Hsiang Shen, Huaying Zhao, Peter W Schuck, Emily J Danoff, Hanh Nguyen, Norihisa Nishimura, Kevin W Bock, Ian N Moore, Peter D Kwong, Robert H Purcell, Sugantha Govindarajan, Patrizia Farci
Publikováno v:
PLoS Pathogens, Vol 16, Iss 8, p e1008793 (2020)
Transmission to chimpanzees of a precore hepatitis B virus (HBV) mutant implicated in acute liver failure (ALF) in humans did not cause ALF nor the classic form of acute hepatitis B (AHB) seen upon infection with the wild-type HBV strain, but rather
Externí odkaz:
https://doaj.org/article/5612fb1e37e748f7a7ed1136e5a4617d
Autor:
Michael D Lewis, Andrea Paun, Audrey Romano, Harry Langston, Charlotte A Langner, Ian N Moore, Kevin W Bock, Amanda Fortes Francisco, Jason M Brenchley, David L Sacks
Publikováno v:
PLoS Pathogens, Vol 16, Iss 4, p e1008456 (2020)
Leishmania donovani causes visceral leishmaniasis (VL), which is typically fatal without treatment. There is substantial variation between individuals in rates of disease progression, response to treatment and incidence of post-treatment sequelae, sp
Externí odkaz:
https://doaj.org/article/af5cfafb500f43f2863c96529f116712
Autor:
Adam S. Cockrell, Joshua C. Johnson, Ian N. Moore, David X. Liu, Kevin W. Bock, Madeline G. Douglas, Rachel L. Graham, Jeffrey Solomon, Lisa Torzewski, Christopher Bartos, Randy Hart, Ralph S. Baric, Reed F. Johnson
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-9 (2018)
Abstract The recurrence of new human cases of Middle East respiratory syndrome coronavirus (MERS-CoV) underscores the need for effective therapeutic countermeasures. Nonhuman primate models are considered the gold standard for preclinical evaluation
Externí odkaz:
https://doaj.org/article/51deb0a819be41de97eecf54819fbc13