Lack of anti-tumour reactivity despite enhanced numbers of circulating natural killer T cells in two patients with metastatic renal cell carcinoma F. A. Vyth-Dreese et al. NK T cells in renal cell carcinoma.

Autor: Vyth-Dreese, F. A.¹ f.vyth@nki.nl, Sein, J.², Van De Kasteele, W.¹, Dellemijn, T. A. M.¹, Van Den Bogaard, C.², Nooijen, W. J.², De Gast, G. C.³, Haanen, J. B. A. G.^1,3, Bex, A.⁴

Publikováno v: Clinical & Experimental Immunology. Dec2010, Vol. 162 Issue 3, p447-459. 13p. 1 Color Photograph, 6 Charts, 4 Graphs.

Phase I trial of combined immunotherapy with subcutaneous granulocyte macrophage colony-stimulating factor, low-dose interleukin 2, and interferon alpha in progressive metastatic melanoma and renal cell carcinoma

Autor: de Gast, G. C., Klümpen, H. J., Vyth-Dreese, F. A., Kersten, M. J., Verra, N. C., Sein, J., Batchelor, D., Nooijen, W. J., Schornagel, J. H.

Publikováno v: Clinical cancer research, 6(4), 1267-1272. American Association for Cancer Research Inc.

The purpose of our study was to determine the maximally tolerated dose (MTD) and DLT of combined administration of granulocyte macrophage colony-stimulating factor (GM-CSF), low-dose interleukin 2 (IL-2) and IFN-alpha in patients with progressive met

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=narcis______::bdc6dd187d1d43fe1cf09151155942e8
https://pure.amc.nl/en/publications/phase-i-trial-of-combined-immunotherapy-with-subcutaneous-granulocyte-macrophage-colonystimulating-factor-lowdose-interleukin-2-and-interferon-alpha-in-progressive-metastatic-melanoma-and-renal-cell-carcinoma(05c303f9-9751-4e5f-b11c-60eecafd4d40).html

Regulatory effect of interleukin-4 (IL-4) on the expression and function of lymphocyte adhesion receptors involved in IL-2-induced cell aggregation

Autor: Vyth-Dreese, F. A., Kooyk, Y., Dellemijn, T. A. M., Melief, C. J. M., Carl Figdor

Publikováno v: Immunology, 78(2), 244-51. Wiley-Blackwell
Vyth-Dreese, F A, Van Kooyk, Y, Dellemijn, T A, Melief, C J & Figdor, C G 1993, ' Regulatory effect of interleukin-4 (IL-4) on the expression and function of lymphocyte adhesion receptors involved in IL-2-induced cell aggregation ', Immunology, vol. 78, no. 2, pp. 244-51 .
Scopus-Elsevier
Immunology, 78, 2, pp. 244-251
Immunology, 78, 244-251. Blackwell science ltd

Human recombinant interleukin-4 (rIL-4) was studied for its capacity to inhibit rIL-2-induced lymphoid cell aggregation. In contrast to rIL-2, rIL-4 was unable to induce cluster formation by itself. However, when added simultaneously with rIL-2 to cu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::7b97c5fa01f913fde434ecba7e0853c3
https://research.vumc.nl/en/publications/73b7f782-58e2-4296-b0cd-e5a432ece41b

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Temozolomide followed by combined immunotherapy with GM-CSF, low-dose IL2 and IFN alpha in patients with metastatic melanoma.

Autor: de Gast, G C, Batchelor, D, Kersten, M J, Vyth-Dreese, F A, Sein, J, van de Kasteele, W F, Nooijen, W J, Nieweg, O E, Waal, M A de, Boogerd, W, de Waal, M A

Publikováno v: British Journal of Cancer; 1/27/2003, Vol. 88 Issue 2, p175-180, 6p