Zobrazeno 1 - 10
of 79
pro vyhledávání: '"Vytas Reipa"'
Autor:
Donald H. Atha, Vytas Reipa
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 6, p 5427 (2023)
As the potential applications of DNA diagnostics continue to expand, there is a need for improved methods and standards for DNA analysis. This report describes several methods that could be considered for the production of reference materials for the
Externí odkaz:
https://doaj.org/article/a956c5e9fcbb4faaad8fe0f7de870979
Publikováno v:
Journal of Nucleic Acids, Vol 2022 (2022)
Application of DNA damage diagnostic tests is rapidly growing, in particular for ovarian, prostate, and skin cancers; environmental monitoring; chronic and degenerative diseases; and male infertility. Such tests suffer from significant variability am
Externí odkaz:
https://doaj.org/article/dc73682a252a4574b5c318a54b009fff
Publikováno v:
Journal of Nucleic Acids, Vol 2020 (2020)
Reference materials are needed to quantify the level of DNA damage in cells, to assess sources of measurement variability and to compare results from different laboratories. The comet assay (single cell gel electrophoresis) is a widely used method to
Externí odkaz:
https://doaj.org/article/8a21cc771699430d80e03f75f836bb87
Publikováno v:
Journal of Nucleic Acids, Vol 2020 (2020)
To evaluate methods for analysis of genotoxic effects on mammalian cell lines, we tested the effect of three common genotoxic agents on Chinese hamster ovary (CHO) cells by single-cell gel electrophoresis (comet assay) and gas chromatography-tandem m
Externí odkaz:
https://doaj.org/article/f52cbe19d05d4856ba1c417f4f8f0ec7
Publikováno v:
Nanomaterials, Vol 11, Iss 8, p 1943 (2021)
Titanium dioxide nanoparticles (TiO2 NPs) have wide commercial applications, owing to their small size; however, the biosafety of TiO2 NPs should be evaluated further. In this study, we aimed to investigate the cytotoxicity of TiO2 NPs in the presenc
Externí odkaz:
https://doaj.org/article/e44aca70fbe7494fb3ffdf7226783050
Publikováno v:
PLoS ONE, Vol 13, Iss 1, p e0190907 (2018)
Exposure of mammalian cells to oxidative stress can result in DNA damage that adversely affects many cell processes. Lack of dependable DNA damage reference materials and standardized measurement methods, despite many case-control studies hampers the
Externí odkaz:
https://doaj.org/article/712ca3f0986d468fbcdae392f105b0a6
Autor:
Vytas Reipa, Donald H. Atha
Publikováno v:
Challenges, Vol 9, Iss 1, p 17 (2018)
With the rapid development of new nanomaterials, it was recognized early that together with their beneficial properties, nanomaterials may pose a risk to human health and the environment. Evidence has accumulated over the last twenty years in support
Externí odkaz:
https://doaj.org/article/f55bbf6624924574a9c8a6cac3477764
Publikováno v:
BioTechniques, Vol 38, Iss 1, Pp 127-132 (2005)
The absorption and emission spectra were measured for Cy™5 and Alexa™ 488 fluorophores confined on a glass surface. The data were obtained using fluorometry and spectroscopic ellipsometry. Red shifts of the surface-immobilized fluorophore absorpt
Externí odkaz:
https://doaj.org/article/8e1b6ec5bb0f4775812961081d66ee79
Publikováno v:
Antioxidants, Vol 5, Iss 3, p 23 (2016)
Oxidative stress in a biological system is often defined as a redox imbalance within cells or groups of cells within an organism. Reductive-oxidative (redox) imbalances in cellular systems have been implicated in several diseases, such as cancer. To
Externí odkaz:
https://doaj.org/article/eb21f3d2c64b4c49a19055a9d955e586
Autor:
Vytas Reipa, Nam Wong Song, Minjeong Kwak, Min Beom Heo, Tae Geol Lee, Paul Westerhoff, Yuqiang Bi, Blaza Toman, Vincent A. Hackley, Haruhisa Kato, Yosuke Tabei, Kanokwan Nontapot, Yonghyun Choi, Jonghoon Choi
Publikováno v:
Nanotoxicology. 16:857-866