Zobrazeno 1 - 10
of 196
pro vyhledávání: '"Vytas A Bankaitis"'
Autor:
Xiao-Ru Chen, Karuna Dixit, Yuan Yang, Mark I McDermott, Hasan Tanvir Imam, Vytas A Bankaitis, Tatyana I Igumenova
Publikováno v:
eLife, Vol 13 (2024)
Regulated hydrolysis of the phosphoinositide phosphatidylinositol(4,5)-bis-phosphate to diacylglycerol and inositol-1,4,5-P3 defines a major eukaryotic pathway for translation of extracellular cues to intracellular signaling circuits. Members of the
Externí odkaz:
https://doaj.org/article/0e0b2fd28a2a439ba2de545a4c16999f
Autor:
Danish Khan, Dongju Lee, Gulcin Gulten, Anup Aggarwal, Joshua Wofford, Inna Krieger, Ashutosh Tripathi, John W Patrick, Debra M Eckert, Arthur Laganowsky, James Sacchettini, Paul Lindahl, Vytas A Bankaitis
Publikováno v:
eLife, Vol 9 (2020)
Yeast Sfh5 is an unusual member of the Sec14-like phosphatidylinositol transfer protein (PITP) family. Whereas PITPs are defined by their abilities to transfer phosphatidylinositol between membranes in vitro, and to stimulate phosphoinositide signali
Externí odkaz:
https://doaj.org/article/33c5c7c3d2734eef83d198b262875ae8
Autor:
Chwee Tat Koe, Ye Sing Tan, Max Lönnfors, Seong Kwon Hur, Christine Siok Lan Low, Yingjie Zhang, Pakorn Kanchanawong, Vytas A Bankaitis, Hongyan Wang
Publikováno v:
eLife, Vol 7 (2018)
A central feature of most stem cells is the ability to self-renew and undergo differentiation via asymmetric division. However, during asymmetric division the role of phosphatidylinositol (PI) lipids and their regulators is not well established. Here
Externí odkaz:
https://doaj.org/article/f89c1270291546408dfdbcb38f7cbefd
Publikováno v:
Journal of Lipid Research, Vol 60, Iss 2, Pp 242-268 (2019)
Phosphoinositides are key regulators of a large number of diverse cellular processes that include membrane trafficking, plasma membrane receptor signaling, cell proliferation, and transcription. How a small number of chemically distinct phosphoinosit
Externí odkaz:
https://doaj.org/article/b7abfe2cbeaf4ce39b3c2c4bac1331d1
Autor:
Emily K. Tribble, Pavlina T. Ivanova, Aby Grabon, James G. Alb, Jr., Irene Faenza, Lucio Cocco, H. Alex Brown, Vytas A. Bankaitis
Publikováno v:
Journal of Lipid Research, Vol 57, Iss 8, Pp 1492-1506 (2016)
A reliable method for purifying envelope-stripped nuclei from immortalized murine embryonic fibroblasts (iMEFs) was established. Quantitative profiling of the glycerophospholipids (GPLs) in envelope-free iMEF nuclei yields several conclusions. First,
Externí odkaz:
https://doaj.org/article/de1c42465ec84552834cb747349a0f90
Structural elements that govern Sec14-like PITP sensitivities to potent small molecule inhibitors[S]
Publikováno v:
Journal of Lipid Research, Vol 57, Iss 4, Pp 650-662 (2016)
Sec14-like phosphatidylinositol transfer proteins (PITPs) play important biological functions in integrating multiple aspects of intracellular lipid metabolism with phosphatidylinositol-4-phosphate signaling. As such, these proteins offer new opportu
Externí odkaz:
https://doaj.org/article/eb7182128aa3442a847fbcd9ce723434
Publikováno v:
Cell Reports, Vol 14, Iss 5, Pp 991-999 (2016)
Summary: Inborn errors of metabolism (IEMs) occur with high incidence in human populations. Especially prevalent among these are inborn deficiencies in fatty acid β-oxidation (FAO), which are clinically associated with developmental neuropsychiatric
Externí odkaz:
https://doaj.org/article/677d4391706e432687a66dd2704b9214
Publikováno v:
bioRxiv
Phosphoinositide metabolism defines the foundation of a major signaling pathway that is conserved throughout the eukaryotic kingdom. The 4-OH phosphorylated phosphoinositides such as phosphatidylinositol-4-phosphate (PtdIns4P) and phosphatidylinosito
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d92904e82c0b931b1867445bc3076f0
https://europepmc.org/articles/PMC9882004/
https://europepmc.org/articles/PMC9882004/
Autor:
Vytas A. Bankaitis, George M. Carman
Publikováno v:
Journal of Lipid Research, Vol 60, Iss 2, Pp 227-228 (2019)
Externí odkaz:
https://doaj.org/article/de6608aaeefa4d2b91a84d7499d10f61
Autor:
Mark A. Bieniawski, Kofi L. P. Stevens, Christopher M. Witham, Robert F. L. Steuart, Vytas A. Bankaitis, Carl J. Mousley
Publikováno v:
International Journal of Molecular Sciences; Volume 23; Issue 20; Pages: 12130
Endoplasmic reticulum (ER) function is dedicated to multiple essential processes in eukaryotes, including the processing of secretory proteins and the biogenesis of most membrane lipids. These roles implicate a heavy burden to the organelle, and it i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a60183f775a00d20e086c2849fa1cfc
https://pubmed.ncbi.nlm.nih.gov/36293008
https://pubmed.ncbi.nlm.nih.gov/36293008