The plasma biomarker soluble SIGLEC-1 is associated with the type I interferon transcriptional signature, ethnic background and renal disease in systemic lupus erythematosus

Autor: Oliveira, JJ, Karrar, S, Rainbow, DB, Pinder, CL, Clarke, P, García, A, Al-Assar, O, Burling, K, Morris, S, Stratton, R, Vyse, TJ, Wicker, LS, Todd, JA, Ferreira, R

Publikováno v: Arthritis Research & Therapy, Vol 20, Iss 1, Pp 1-13 (2018)

Background The molecular heterogeneity of autoimmune and inflammatory diseases has been one of the main obstacles to the development of safe and specific therapeutic options. Here, we evaluated the diagnostic and clinical value of a robust, inexpensi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::bfc5d3f3c497b31828aa7e759ccbba31
https://www.repository.cam.ac.uk/handle/1810/278528

The development of genome-wide association studies and their application to complex diseases, including lupus.

Autor: Bentham, J, Vyse, TJ¹

Publikováno v: Lupus. Oct2013, Vol. 22 Issue 12, p1205-1213. 9p. 1 Diagram, 1 Chart.

GWAS identifies novel SLE susceptibility genes and explains the association of the HLA region

Autor: Criswell, Lindsey, Armstrong, DL, Zidovetzki, R, Alarcón-Riquelme, ME, Tsao, BP, Criswell, LA, Kimberly, RP, Harley, JB, Sivils, KL, Vyse, TJ, Gaffney, PM

Publikováno v: Criswell, Lindsey; Armstrong, DL; Zidovetzki, R; Alarcón-Riquelme, ME; Tsao, BP; Criswell, LA; et al.(2014). GWAS identifies novel SLE susceptibility genes and explains the association of the HLA region. UC San Francisco: Retrieved from: http://www.escholarship.org/uc/item/07f1r0h5

In a genome-wide association study (GWAS) of individuals of European ancestry afflicted with systemic lupus erythematosus (SLE) the extensive utilization of imputation, step-wise multiple regression, lasso regularization and increasing study power by

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______325::7cbce16e2ed4a7d2884a9a4b8f585a81
http://www.escholarship.org/uc/item/07f1r0h5

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