Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Vv, Liakhovich"'
Publikováno v:
Europe PubMed Central
The authors' rat experiments have shown that inhibition of pro-oxidant reactions in hepatocyte microsomal fraction in response to hepatic exposure to low-intensive IR-laser radiation and low-intensity ultrasound combines with multidirectional action
Publikováno v:
Europe PubMed Central
The activity changes of cytochrome P-450-dependent monooxygenases of hepatic microsomal fraction were studied in, experimental animals after prolonged application (1 month) of low radiation doses (0.258 mkl/kg). The obtained results show the increase
Publikováno v:
Europe PubMed Central
The experiments on 130 rat males have shown that the exposure of the animals' liver to centimeter microwaves enhances catalytic activity of P-450p cytochrome, an enzyme of drug microsomal metabolism. However, changes in pharmacokinetic parameters of
Publikováno v:
Europe PubMed Central
Effects of pyridine and pyridine-N-oxide on the monooxygenase system of rat liver microsomes have been studied. Pyridine (200 mg/kg) increased total cytochrome P-450 content and activated metabolism of some specific substrates 24 hours after injectio
Autor:
Ta, Zolotareva, Ga, Gorchakova, Vl, Konovalenko, Ln, Konovalenko, Alevtina Grishanova, Lf, Guliaeva, Vv, Liakhovich
Publikováno v:
Europe PubMed Central
In experiments on male Wistar rats it has been found that physical factors applied in medicine (laser radiation of low intensity with wave length 0.89 microns, microwaves of centimeter range of 2450 MHz, and ultrasound of low intensity 880 KHz) chang
Publikováno v:
Europe PubMed Central
The synthesis of pharmacologically active diazepam metabolites (oxazepam, 4-hydroxydiazepam, N-demethyldiazepam) in liver microsomes of intact and phenobarbital-, 3-methylcholanthrene- and dexamethasone-induced male and female Wistar rats as well as
Publikováno v:
Europe PubMed Central
The reconstitution of microsomal membrane monooxygenase system with variable contents of the hydroxylating chain enzymatic components was carried out. It was found that during self-assembly of microsomal membranes solubilized with 4% sodium cholate a
Publikováno v:
Europe PubMed Central
Solubilization of liver microsomes of intact, phenobarbital-treated and 3-methylcholantrene-treated rats was investigated. It was shown that treatment of microsomes with 4% sodium cholate leads to separation of proteins and phospholipids from the mic
Publikováno v:
Europe PubMed Central
Changes in the metabolic activity of 7-ethoxyresorufin in rat liver microsomes containing different amounts of cytochrome P-450 induced by 3-methylcholanthrene and other polycyclic hydrocarbons (P-450c) were studied. Using antibodies to cytochrome P-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::5322d70cbef88819de17236620e7a586
http://europepmc.org/abstract/med/3179354
http://europepmc.org/abstract/med/3179354
Publikováno v:
Europe PubMed Central
The activity and content of CYP1A1, CYP1A2, CYP2B1 and CYP2B in the liver, lung and kidney of Wistar rats treated with hexachlorobenzene (HCB), Aroclor 1254 (AR), methylcholanthrene (MC) and phenobarbital (PB) were studied. Administration of MC and A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::046e737326a2304f49b9887383120278
http://europepmc.org/abstract/med/8018775
http://europepmc.org/abstract/med/8018775