SHANK3 depletion leads to ERK signalling overdose and cell death in KRAS-mutant cancers.

Autor: Lilja J; Turku Bioscience Centre, University of Turku, FI-20520, Turku, Finland., Kaivola J; Turku Bioscience Centre, University of Turku, FI-20520, Turku, Finland., Conway JRW; Turku Bioscience Centre, University of Turku, FI-20520, Turku, Finland., Vuorio J; Department of Physics, University of Helsinki, Helsinki, Finland., Parkkola H; Turku Bioscience Centre, University of Turku, FI-20520, Turku, Finland., Roivas P; Turku Bioscience Centre, University of Turku, FI-20520, Turku, Finland.; Institute of Biomedicine, University of Turku, FI-20520, Turku, Finland., Dibus M; Turku Bioscience Centre, University of Turku, FI-20520, Turku, Finland., Chastney MR; Turku Bioscience Centre, University of Turku, FI-20520, Turku, Finland., Varila T; Turku Bioscience Centre, University of Turku, FI-20520, Turku, Finland., Jacquemet G; Turku Bioscience Centre, University of Turku, FI-20520, Turku, Finland.; Faculty of Science and Engineering, Cell Biology, Åbo Akademi University, FI-20520, Turku, Finland.; Turku Bioimaging, University of Turku and Åbo Akademi University, FI-20520, Turku, Finland.; InFLAMES Research Flagship Center, Åbo Akademi University, FI-20520, Turku, Finland., Peuhu E; Turku Bioscience Centre, University of Turku, FI-20520, Turku, Finland.; Institute of Biomedicine, Cancer Research Laboratory FICAN West, University of Turku, FI-20520, Turku, Finland., Wang E; Institute of Systems, Molecular and Integrative Biology, University of Liverpool, Liverpool, UK., Pentikäinen U; Turku Bioscience Centre, University of Turku, FI-20520, Turku, Finland.; Institute of Biomedicine, University of Turku, FI-20520, Turku, Finland., Martinez D Posada I; Turku Bioscience Centre, University of Turku, FI-20520, Turku, Finland., Hamidi H; Turku Bioscience Centre, University of Turku, FI-20520, Turku, Finland., Najumudeen AK; Institute of Biotechnology, HiLIFE, University of Helsinki, Helsinki, Finland.; CRUK Scotland Institute, Garscube Estate, Switchback Road, Glasgow, G61 1BD, UK., Sansom OJ; CRUK Scotland Institute, Garscube Estate, Switchback Road, Glasgow, G61 1BD, UK.; Institute of Cancer Sciences, University of Glasgow, Garscube Estate, Switchback Road, Glasgow, G61 1QH, UK., Barsukov IL; Institute of Systems, Molecular and Integrative Biology, University of Liverpool, Liverpool, UK., Abankwa D; Turku Bioscience Centre, University of Turku, FI-20520, Turku, Finland.; Department of Life Sciences and Medicine, University of Luxembourg, 4365, Esch- sur-Alzette, Luxembourg., Vattulainen I; Department of Physics, University of Helsinki, Helsinki, Finland., Salmi M; Institute of Biomedicine, University of Turku, FI-20520, Turku, Finland.; MediCity Research Laboratory, University of Turku, FI-20520, Turku, Finland.; InFLAMES Research Flagship Center, University of Turku, FI-20520, Turku, Finland., Ivaska J; Turku Bioscience Centre, University of Turku, FI-20520, Turku, Finland. Johanna.ivaska@utu.fi.; InFLAMES Research Flagship Center, University of Turku, FI-20520, Turku, Finland. Johanna.ivaska@utu.fi.; Department of Life Technologies, University of Turku, Turku, Finland. Johanna.ivaska@utu.fi.; Foundation for the Finnish Cancer Institute, Tukholmankatu 8, FI-00014, Helsinki, Finland. Johanna.ivaska@utu.fi.; Western Finnish Cancer Center, University of Turku, Turku, FI-20520, Finland. Johanna.ivaska@utu.fi.

Publikováno v: Nature communications [Nat Commun] 2024 Sep 12; Vol. 15 (1), pp. 8002. Date of Electronic Publication: 2024 Sep 12.

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PO-1593 Real-world electronic patient reported outcome utilization in patients receiving radiation therapy

Autor: Kudel, I., Curry, H., Pennanen, P., Lahelma, M., Vuorio, J., Leskelä, R., Shamsi, Z., Bärlund, M.

Publikováno v: In Radiotherapy and Oncology May 2023 182 Supplement 1:S1293-S1294

The development of early numeracy skills in kindergarten in low-, average- and high-performance groups

Autor: Aunio, P., Heiskari, P., van Luit, J.E.H., Vuorio, J.-M., Leerstoel Luit, Education and Learning: Cognitive and Motor Disabilities

Publikováno v: Journal of Early Childhood Research, 13, 3. SAGE Publications Ltd

In this study, we investigated how early numeracy skills develop in kindergarten-age children. The participants were 235 Finnish children (111 girls and 124 boys). At the time of the first measurement, the average age of the children was 6 years. The

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4d0aacb13c2b43a91ed84a945da70ea
https://doi.org/10.1177/1476718x14538722

N-Glycosylation can selectively block or foster different receptor-ligand binding modes.

Autor: Vuorio J; Department of Physics, University of Helsinki, P.O. Box 64, 00014, Helsinki, Finland.; Computational Physics Laboratory, Tampere University, PO Box 692, 33014, Tampere, Finland., Škerlová J; Institute of Molecular Genetics, Czech Academy of Sciences, Videnska 1083, 142 20, Prague 4, Czech Republic.; Institute of Organic Chemistry and Biochemistry, Czech Academy of Sciences, Flemingovo nam. 2, 166 10, Prague 6, Czech Republic., Fábry M; Institute of Molecular Genetics, Czech Academy of Sciences, Videnska 1083, 142 20, Prague 4, Czech Republic., Veverka V; Institute of Organic Chemistry and Biochemistry, Czech Academy of Sciences, Flemingovo nam. 2, 166 10, Prague 6, Czech Republic.; Department of Cell Biology, Faculty of Science, Charles University, Vinicna 7, 128 00, Prague, Czech Republic., Vattulainen I; Department of Physics, University of Helsinki, P.O. Box 64, 00014, Helsinki, Finland.; Computational Physics Laboratory, Tampere University, PO Box 692, 33014, Tampere, Finland.; MEMPHYS-Centre for Biomembrane Physics, Odense, Denmark., Řezáčová P; Institute of Molecular Genetics, Czech Academy of Sciences, Videnska 1083, 142 20, Prague 4, Czech Republic.; Institute of Organic Chemistry and Biochemistry, Czech Academy of Sciences, Flemingovo nam. 2, 166 10, Prague 6, Czech Republic., Martinez-Seara H; Institute of Organic Chemistry and Biochemistry, Czech Academy of Sciences, Flemingovo nam. 2, 166 10, Prague 6, Czech Republic. hseara@gmail.com.

Publikováno v: Scientific reports [Sci Rep] 2021 Mar 04; Vol. 11 (1), pp. 5239. Date of Electronic Publication: 2021 Mar 04.