Zobrazeno 1 - 10
of 70
pro vyhledávání: '"Vukica Šrajer"'
Autor:
Rick A. Hewitt, Kevin M. Dalton, Derek A. Mendez, Harrison K. Wang, Margaret A. Klureza, Dennis E. Brookner, Jack B. Greisman, David McDonagh, Vukica Šrajer, Nicholas K. Sauter, Aaron S. Brewster, Doeke R. Hekstra
Publikováno v:
Structural Dynamics, Vol 11, Iss 5, Pp 054701-054701-16 (2024)
Most x-ray sources are inherently polychromatic. Polychromatic (“pink”) x-rays provide an efficient way to conduct diffraction experiments as many more photons can be used and large regions of reciprocal space can be probed without sample rotatio
Externí odkaz:
https://doaj.org/article/4662ac0f09db4c5dae78a869c55697a1
Autor:
Robert W. Henning, Irina Kosheleva, Vukica Šrajer, In-Sik Kim, Eric Zoellner, Rama Ranganathan
Publikováno v:
Structural Dynamics, Vol 11, Iss 1, Pp 014301-014301-15 (2024)
A major goal in biomedical science is to move beyond static images of proteins and other biological macromolecules to the internal dynamics underlying their function. This level of study is necessary to understand how these molecules work and to engi
Externí odkaz:
https://doaj.org/article/0dfc439752524ddc9304d7b24acd7f47
Autor:
Tadeo Moreno-Chicano, Leiah M. Carey, Danny Axford, John H. Beale, R. Bruce Doak, Helen M. E. Duyvesteyn, Ali Ebrahim, Robert W. Henning, Diana C. F. Monteiro, Dean A. Myles, Shigeki Owada, Darren A. Sherrell, Megan L. Straw, Vukica Šrajer, Hiroshi Sugimoto, Kensuke Tono, Takehiko Tosha, Ivo Tews, Martin Trebbin, Richard W. Strange, Kevin L. Weiss, Jonathan A. R. Worrall, Flora Meilleur, Robin L. Owen, Reza A. Ghiladi, Michael A. Hough
Publikováno v:
IUCrJ, Vol 9, Iss 5, Pp 610-624 (2022)
Room-temperature macromolecular crystallography allows protein structures to be determined under close-to-physiological conditions, permits dynamic freedom in protein motions and enables time-resolved studies. In the case of metalloenzymes that are h
Externí odkaz:
https://doaj.org/article/288bb78b21864584a71fa98e261fa74e
Autor:
Juan C. Sanchez, Melissa Carrillo, Suraj Pandey, Moraima Noda, Luis Aldama, Denisse Feliz, Elin Claesson, Weixiao Yuan Wahlgren, Gregory Tracy, Phu Duong, Angela C. Nugent, Andrew Field, Vukica Šrajer, Christopher Kupitz, So Iwata, Eriko Nango, Rie Tanaka, Tomoyuki Tanaka, Luo Fangjia, Kensuke Tono, Shigeki Owada, Sebastian Westenhoff, Marius Schmidt, Emina A. Stojković
Publikováno v:
Structural Dynamics, Vol 6, Iss 5, Pp 054701-054701-9 (2019)
Phytochromes (PHYs) are photoreceptor proteins first discovered in plants, where they control a variety of photomorphogenesis events. PHYs as photochromic proteins can reversibly switch between two distinct states: a red light (Pr) and a far-red ligh
Externí odkaz:
https://doaj.org/article/1fd0d969f1804a91a9ec628832ae62aa
Autor:
So Iwata, Shigeki Owada, Michał Maj, Denisse Feliz, Tomoyuki Tanaka, Marius Schmidt, Luis Aldama, Sebastian Westenhoff, Rie Tanaka, Melissa Carrillo, Moraima Noda, Suraj Pandey, Juan Sanchez, Emina A. Stojković, Weixiao Yuan Wahlgren, Elin Claesson, Leticia Castillon, Eriko Nango, K. Tono, Ishwor Poudyal, Luo Fangjia, Tek Narsingh Malla, Vukica Šrajer
Publikováno v:
Structure
Phytochromes are red/far-red light photoreceptors in bacteria to plants, which elicit a variety of important physiological responses. They display a reversible photocycle between the resting (dark) Pr state and the light activated Pfr state, in which
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e79378e146bb21ff37a5140fbea7495
https://pubmed.ncbi.nlm.nih.gov/33756101
https://pubmed.ncbi.nlm.nih.gov/33756101
Autor:
Shuo Sui, Christos D. Dimitrakopoulos, Sarah L. Perry, Kristopher W. Kolewe, Robert Henning, Jessica D. Schiffman, Yuxi Wang, Vukica Šrajer
Publikováno v:
Lab on a Chip. 16:3082-3096
Microfluidic strategies to enable the growth and subsequent serial crystallographic analysis of micro-crystals have the potential to facilitate both structural characterization and dynamic structural studies of protein targets that have been resistan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7c04949dbe9b31193a3c516fcba6ee6
https://doi.org/10.1039/c6lc00451b
https://doi.org/10.1039/c6lc00451b
Publikováno v:
Journal of Synchrotron Radiation, Vol 30, Iss 2, Pp 490-499 (2023)
A fundamental problem in biological sciences is understanding how macromolecular machines work and how the structural changes of a molecule are connected to its function. Time-resolved techniques are vital in this regard and essential for understandi
Externí odkaz:
https://doaj.org/article/65e659961b7c474181726451cfbdb8f3
Autor:
Gerrit Groenhof, Vukica Šrajer, Irina Kosheleva, Marius Kaucikas, Ann Fitzpatrick, Jasper J. van Thor, Elana Bryan, Abelone Struve, Robert Henning
Publikováno v:
Proteins: Structure, Function, and Bioinformatics. 83:397-402
The fluorescent protein Dronpa undergoes reversible photoswitching reactions between the bright ‘on’ and dark ‘off’ states via photoisomerisation and proton transfer reactions. We report the room temperature crystal structure of the fast swit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2654c65178d018c923b04258916b99b2
https://doi.org/10.1002/prot.24742
https://doi.org/10.1002/prot.24742
Autor:
Marius Schmidt, Vukica Šrajer
Macromolecular crystallography was immensely successful in the last two decades. To a large degree this success resulted from use of powerful third generation synchrotron X-ray sources. An expansive database of more than 100,000 protein structures, o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39c5ec0d47a6360ed4cdd604a183a198
https://europepmc.org/articles/PMC5771432/
https://europepmc.org/articles/PMC5771432/
Autor:
Sudipto Guha, Vukica Šrajer, Ashtamurthy S. Pawate, Zhong Ren, Robert Henning, Sarah L. Perry, Paul J. A. Kenis, Irina Kosheleva
Publikováno v:
Journal of Applied Crystallography. 47:1975-1982
Renewed interest in room-temperature diffraction has been prompted by the desire to observe structural dynamics of proteins as they function. Serial crystallography, an experimental strategy that aggregates small pieces of data from a large uniform p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38c821d4d6cd6fe24aa4c5a98b51aa62
https://doi.org/10.1107/s1600576714023322
https://doi.org/10.1107/s1600576714023322