Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Vuk Koprivica"'
Publikováno v:
Toxins, Vol 14, Iss 3, p 225 (2022)
Vibrio cholerae uses cholera toxin (CT) to cause cholera, a severe diarrheal disease in humans that can lead to death within hours of the onset of symptoms. The catalytic activity of CT in target epithelial cells increases cellular levels of 3′,5
Externí odkaz:
https://doaj.org/article/b6b5fd7629a746f3b025361b058555af
Autor:
Prabhakaran Kumar, Manikannan Mathayan, Sandra P. Smieszek, Bartlomiej P. Przychodzen, Vuk Koprivica, Gunther Birznieks, Mihael H. Polymeropoulos, Bellur S. Prabhakar
Publikováno v:
Virology. 572:64-71
Recurrent waves of COVID19 remain a major global health concern. Repurposing either FDA-approved or clinically advanced drug candidates can save time and effort required for validating the safety profile and FDA approval. However, the selection of ap
Autor:
Prabhakaran Kumar, Kiira M Ratia, Justin M Richner, Gregory R J Thatcher, Rashmi Kadam, Sandra P Smieszek, Bartlomiej P Przychodzen, Vuk Koprivica, Gunther Birznieks, Mihael H Polymeropoulos, Bellur S Prabhakar
Recurrent waves of SARS CoV2 infections remain a major global health concern. Emergence of highly infectious variants with reduced sensitivity to neutralization by vaccines and monoclonal antibodies (mAb) necessitates a deeper understanding of factor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9dd302cf5dcc9f2bd1293531786f9663
https://doi.org/10.1101/2022.02.09.479835
https://doi.org/10.1101/2022.02.09.479835
Autor:
Karen Regardie, Yoshihiro Tadori, Ruoyan Chen, Janelle L. Johnson, Tetsuro Kikuchi, Vuk Koprivica, Hisashi Kitagawa, Shaun Jordan, Junichi Kambayashi
Publikováno v:
Progress in Neuro-Psychopharmacology and Biological Psychiatry. 31:348-356
Clinical evidence suggests that dopamine D(2) receptor partial agonists must have a sufficiently low intrinsic activity to be effective as antipsychotics. Here, we used dopamine D(2) receptor signaling assays to compare the in vitro functional charac
Autor:
Kin-Sang Cho, Marc Tessier-Lavigne, Glenn Yiu, Zhigang He, Estelle Lin, Jasvinder K. Atwal, Jieun Kim, Jong Bae Park, Dong Feng Chen, Bryan Gore, Vuk Koprivica
Publikováno v:
Science. 310:106-110
Inhibitory molecules associated with myelin and the glial scar limit axon regeneration in the adult central nervous system (CNS), but the underlying signaling mechanisms of regeneration inhibition are not fully understood. Here, we show that suppress
Autor:
Zhigang He, Vuk Koprivica
Publikováno v:
Annual Review of Neuroscience. 27:341-368
▪ Abstract A hostile environment and decreased regenerative capacity may contribute to the failure of axon regeneration in the adult central nervous system. Recent studies leading to the identification of several myelin-associated inhibitors and th
Autor:
Katsura Tottori, C. Anthony Altar, Vuk Koprivica, Tetsuro Kikuchi, Shaun Jordan, Robert W. Dunn
Publikováno v:
European Journal of Pharmacology. 483:45-53
In vivo microdialysis was used to monitor the effects of oral aripiprazole and olanzapine on basal extracellular concentrations of dopamine, 3,4-dihydroxyphenylacetic acid (DOPAC), homovanillic acid (HVA) and 5-hydroxyindole acetic acid (5-HIAA) in t
Autor:
Yong Guo, Rajeev Sivasankaran, Zhigang He, Kevin C. Wang, Rachel L. Neve, Jieun Kim, Vuk Koprivica
Publikováno v:
Nature. 417:941-944
The inhibitory activity associated with myelin is a major obstacle for successful axon regeneration in the adult mammalian central nervous system (CNS)1,2. In addition to myelin-associated glycoprotein (MAG)3,4 and Nogo-A5,6,7, available evidence sug
Autor:
Christina Wolff, Vuk Koprivica, Tetsuro Kikuchi, Shaun Jordan, Junichi Kambayashi, Karen Regardie, Janelle Johnson Murphy, Raymond Fernalld
Publikováno v:
European journal of pharmacology. 651(1-3)
Neurodegeneration is thought to be a component of schizophrenia pathology, and some antipsychotics appear to slow degenerative changes in patients. Aripiprazole, the first partial dopamine D2 receptor agonist approved for the treatment of schizophren
Autor:
Shaun Jordan, Tetsuro Kikuchi, Katsura Tottori, Vuk Koprivica, Ronald L. Hamilton, Ruoyan Chen, Richard Whitehead
Publikováno v:
European journal of pharmacology. 517(3)
This study determined the in vitro functional profile of 1-[3-[4-(3-chlorophenyl)-1-piperazinyl]propyl]-5-methoxy-3,4-dihydro-2-quinolinone monomethanesulfonate (OPC-14523) at rat and human serotonin (5-HT) 5-HT1A receptors and binding affinity of OP