Zobrazeno 1 - 10
of 107
pro vyhledávání: '"Vu Thuy Khanh Le‐Trilling"'
Autor:
Binli Mao, Vu Thuy Khanh Le-Trilling, Haihuan Tang, Jie Hu, Mona S. Schmitz, Kimberly Barbet, Dan Xu, Zhen Wei, Beinu Guo, Denise Mennerich, Chun Yao, Jinxin Liu, Zhenghan Li, Yushun Wan, Xiaoyong Zhang, Kai Wang, Ni Tang, Zebo Yu, Mirko Trilling, Yong Lin
Publikováno v:
Virus Research, Vol 350, Iss , Pp 199485- (2024)
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) caused the coronavirus disease 2019 (COVID-19) pandemic, posing serious threats to global health. Effective broad-spectrum antiviral drugs for the treatment of COVID-19 are not sufficie
Externí odkaz:
https://doaj.org/article/f0d67e25f0bf4a0bb63266f847d22bd6
Autor:
Alexander Thomas, Thomas Battenfeld, Ivana Kraiselburd, Olympia Anastasiou, Ulf Dittmer, Ann-Kathrin Dörr, Adrian Dörr, Carina Elsner, Jule Gosch, Vu Thuy Khanh Le-Trilling, Simon Magin, René Scholtysik, Pelin Yilmaz, Mirko Trilling, Lara Schöler, Johannes Köster, Folker Meyer
Publikováno v:
BMC Genomics, Vol 25, Iss 1, Pp 1-9 (2024)
Abstract Background At a global scale, the SARS-CoV-2 virus did not remain in its initial genotype for a long period of time, with the first global reports of variants of concern (VOCs) in late 2020. Subsequently, genome sequencing has become an indi
Externí odkaz:
https://doaj.org/article/7c88bf5065d14a7caf6ac89a4da96eec
Autor:
Carolin Gerke, Liane Bauersfeld, Ivo Schirmeister, Chiara Noemi-Marie Mireisz, Valerie Oberhardt, Lea Mery, Di Wu, Christopher Sebastian Jürges, Robbert M Spaapen, Claudio Mussolino, Vu Thuy Khanh Le-Trilling, Mirko Trilling, Lars Dölken, Wolfgang Paster, Florian Erhard, Maike Hofmann, Andreas Schlosser, Hartmut Hengel, Frank Momburg, Anne Halenius
Publikováno v:
eLife, Vol 13 (2024)
Human leucocyte antigen class I (HLA-I) molecules play a central role for both NK and T-cell responses that prevent serious human cytomegalovirus (HCMV) disease. To create opportunities for viral spread, several HCMV-encoded immunoevasins employ dive
Externí odkaz:
https://doaj.org/article/c867fd290b5f4af9870c2dc3f63a87b4
Autor:
Clara Di Vito, Nicolò Coianiz, Michela Calvi, Sara Terzoli, Elisa Zaghi, Simone Puccio, Alessandro Frigo, Jacopo Mariotti, Chiara De Philippis, Daniele Mannina, Barbara Sarina, Rossana Mineri, Vu Thuy Khanh Le-Trilling, Mirko Trilling, Luca Castagna, Stefania Bramanti, Armando Santoro, Domenico Mavilio
Publikováno v:
Frontiers in Immunology, Vol 14 (2024)
Haploidentical hematopoietic stem cell transplantation (h-HSCT) is a therapeutic option to cure patients affected by hematologic malignancies. The kinetics and the quality of immune-reconstitution (IR) impact the clinical outcome of h-HSCT and limit
Externí odkaz:
https://doaj.org/article/ff1e1518e9bd4fbda530dbd55204e118
Autor:
Julian Gonzalez-Rubio, Vu Thuy Khanh Le-Trilling, Lea Baumann, Maria Cheremkhina, Hannah Kubiza, Anja E. Luengen, Sebastian Reuter, Christian Taube, Stephan Ruetten, Daniela Duarte Campos, Christian G. Cornelissen, Mirko Trilling, Anja Lena Thiebes
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 11 (2023)
Introduction: The Severe acute respiratory syndrome coronavirus type 2 (SARS-CoV-2), which caused the coronavirus disease 2019 (COVID-19) pandemic, enters the human body via the epithelial cells of the airway tract. To trap and eject pathogens, the a
Externí odkaz:
https://doaj.org/article/f28e7f99ee7b4a2abc7feccf177ffcb3
Autor:
Vu Thuy Khanh Le-Trilling, Andreja Jagnjić, Ilija Brizić, Mareike Eilbrecht, Kerstin Wohlgemuth, Carmen Rožmanić, Alan Herdman, Katja Hoffmann, Astrid M. Westendorf, Hartmut Hengel, Stipan Jonjić, Mirko Trilling
Publikováno v:
npj Vaccines, Vol 8, Iss 1, Pp 1-13 (2023)
Abstract Human cytomegalovirus (HCMV) frequently causes congenital infections, resulting in birth defects and developmental disorders. A vaccine is needed, but unavailable. We analyzed the potential of CMV mutants, lacking their STAT2 antagonists to
Externí odkaz:
https://doaj.org/article/5bb5e1a25fb24a2880eaea087eec9796
Autor:
Binli Mao, Vu Thuy Khanh Le-Trilling, Kai Wang, Denise Mennerich, Jie Hu, Zhenyu Zhao, Jiaxin Zheng, Yingying Deng, Benjamin Katschinski, Shilei Xu, Guiji Zhang, Xuefei Cai, Yuan Hu, Jianwei Wang, Mengji Lu, Ailong Huang, Ni Tang, Mirko Trilling, Yong Lin
Publikováno v:
Emerging Microbes and Infections, Vol 11, Iss 1, Pp 483-497 (2022)
Coronavirus disease 2019 (COVID-19) caused by the emerging severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has set off a global pandemic. There is an urgent unmet need for safe, affordable, and effective therapeutics against COVID-19. In
Externí odkaz:
https://doaj.org/article/2cc623b759fd4f6bbe6c4382c628268d
Autor:
Vu Thuy Khanh Le-Trilling, Denise Mennerich, Corinna Schuler, Roman Sakson, Julia K. Lill, Siva Swapna Kasarla, Dominik Kopczynski, Stefan Loroch, Yulia Flores-Martinez, Benjamin Katschinski, Kerstin Wohlgemuth, Matthias Gunzer, Folker Meyer, Prasad Phapale, Ulf Dittmer, Albert Sickmann, Mirko Trilling
Publikováno v:
BMC Biology, Vol 20, Iss 1, Pp 1-21 (2022)
Abstract Background The SARS-CoV-2/COVID-19 pandemic has inflicted medical and socioeconomic havoc, and despite the current availability of vaccines and broad implementation of vaccination programs, more easily accessible and cost-effective acute tre
Externí odkaz:
https://doaj.org/article/64f1ee9cf6624323968912e635fb6b3a
Autor:
Vu Thuy Khanh Le-Trilling, Fabienne Maaßen, Benjamin Katschinski, Hartmut Hengel, Mirko Trilling
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Human cytomegalovirus (HCMV) is a prototypical β-herpesvirus which frequently causes morbidity and mortality in individuals with immature, suppressed, or senescent immunity. HCMV is sensed by various pattern recognition receptors, leading to the sec
Externí odkaz:
https://doaj.org/article/9fecab2ab8a842689a4c4bc3d89234af
Autor:
Caroline Holtkamp, Lara Schöler, Olympia E. Anastasiou, Bastian Brune, Kai Fessmann, Carina Elsner, Birte Möhlendick, Ieva Čiučiulkaitė, Marcel Dudda, Mirko Trilling, Ulf Dittmer, Jörg Spors, Vu Thuy Khanh Le-Trilling
Publikováno v:
Heliyon, Vol 9, Iss 1, Pp e12746- (2023)
Knowledge regarding the sustainability of immune responses after COVID-19 vaccination is important, e.g., to decide whom and when to booster. Thus, we analyzed antibody titers in firefighters six months after vaccination with the mRNA-based vaccine C
Externí odkaz:
https://doaj.org/article/f99fe46316c04cd5b7ec510571ac99a1