Enhanced anticancer efficacy of TRAIL-conjugated and odanacatib-loaded PLGA nanoparticles in TRAIL resistant cancer.

Autor: Nguyen TTK; College of Pharmacy, Keimyung University, Daegu, 42602, Republic of Korea; Department of Precision Medicine, School of Medicine, Sungkyunkwan University, Suwon, Gyeonggi, 16419, Republic of Korea., Woo SM; Department of Immunology, School of medicine, Keimyung University, Daegu, Republic of Korea., Seo SU; Department of Immunology, School of medicine, Keimyung University, Daegu, Republic of Korea., Banstola A; Department of Dermatology, Harvard Medical School, Wellman Center for Photomedicine, Massachusetts General Hospital, Boston, MA, USA., Kim H; College of Pharmacy, Keimyung University, Daegu, 42602, Republic of Korea., Duwa R; Department of Biopharmaceutical Convergence, Sungkyunkwan University, Suwon, 16419, Republic of Korea; Department of Radiology, Molecular Imaging Program at Stanford (MIPS), School of medicine, Stanford University, Stanford, CA, 94305, USA., Vu ATT; College of Pharmacy, Keimyung University, Daegu, 42602, Republic of Korea., Hong IS; Department of Molecular Medicine, School of Medicine, Gachon University, Incheon, 406-840, Republic of Korea., Kwon TK; Department of Immunology, School of medicine, Keimyung University, Daegu, Republic of Korea; Center for Forensic Pharmaceutical Science, Keimyung University, Daegu, 42601, Republic of Korea. Electronic address: kwontk@dsmc.or.kr., Yook S; Department of Biopharmaceutical Convergence, Sungkyunkwan University, Suwon, 16419, Republic of Korea; School of Pharmacy, Sungkyunkwan University, Suwon, 16419, Republic of Korea. Electronic address: ysimmyung@skku.edu.

Publikováno v: Biomaterials [Biomaterials] 2025 Jan; Vol. 312, pp. 122733. Date of Electronic Publication: 2024 Jul 30.