Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Vsevolod V. Pavshintsev"'
Autor:
Anton V. Malyshev, Iuliia A. Sukhanova, Alexander S. Zlobin, Vasilina R. Gedzun, Vsevolod V. Pavshintsev, Ekaterina V. Vasileva, Arthur O. Zalevsky, Igor I. Doronin, Nikita A. Mitkin, Andrey V. Golovin, Maxim L. Lovat, Georgy I. Kovalev, Yurii A. Zolotarev, Askar R. Kuchumov, Gennady A. Babkin, Bernhard Luscher
Publikováno v:
Frontiers in Neuroscience, Vol 15 (2021)
The aim of the study was to develop better anxiolytics and antidepressants. We focused on GABAA receptors and the α2δ auxiliary subunit of V-gated Ca2+ channels as putative targets because they are established as mediators of efficacious anxiolytic
Externí odkaz:
https://doaj.org/article/744533a44c374b5489533f40fc433b89
Autor:
Anton V. Malyshev, Iuliia A. Sukhanova, Valeria M. Ushakova, Yana A. Zorkina, Olga V. Abramova, Anna Y. Morozova, Eugene A. Zubkov, Nikita A. Mitkin, Vsevolod V. Pavshintsev, Igor I. Doronin, Vasilina R. Gedzun, Gennady A. Babkin, Sergio A. Sanchez, Miah D. Baker, Colin N. Haile
Publikováno v:
Pharmaceuticals, Vol 15, Iss 4, p 462 (2022)
We have previously described the LCGA-17 peptide as a novel anxiolytic and antidepressant candidate that acts through the α2δ VGCC (voltage-gated calcium channel) subunit with putative synergism with GABA-A receptors. The current study tested the p
Externí odkaz:
https://doaj.org/article/eba1a1865ee04e8eb42573053d2d6eb5
Autor:
Petr K. Anokhin, Olga Y. Frolova, Maria V. Belopolskaya, Vsevolod V. Pavshintsev, Ekaterina A. Kushnir, Maxim L. Lovat, Nikita A. Mitkin
Publikováno v:
Alcohol. 83:17-28
Chronic ethanol consumption in high doses is associated with constitutively elevated activity of the serum alcohol dehydrogenase I (ADH I) isoform, which demonstrates a high affinity not only for ethanol but also for a number of bioamine metabolites.
Autor:
Marina A. Afanasyeva, Dmitry V. Kuprash, Vsevolod V. Pavshintsev, Konstantin A. Rumyantsev, A N Uvarova, A. M. Schwartz, Nikita A. Mitkin, Kirill V. Korneev, Murad Vagida, Alisa M. Muratova
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease. 1864:3211-3220
CD58 is expressed on the surface of antigen-presenting cells, including B-cells, and provides co-stimulation to regulatory T-cells (Treg) through CD2 receptor binding. Tregs appear to be essential suppressors of tissue-specific autoimmune responses.
Autor:
Nikita A. Mitkin, O. A. Averina, Maxim L. Lovat, Vsevolod V. Pavshintsev, Ekaterina A. Kushnir, Olga Y. Frolova
Publikováno v:
Physiologybehavior. 179
Alcohol dehydrogenases (ADH) are key enzymes of ethanol metabolism that mediate its oxidation to acetaldehyde. ADHs are also able to oxidize some types of neurotransmitters such as dopamine, serotonin and norepinephrine. Increased level of ADHs activ
Autor:
Victoria Ostapenko, Maxim V. Skulachev, A. Y. Savchenko, Alexander N. Lukashev, Vsevolod V. Pavshintsev, Vladimir P. Skulachev
It has been about 15 years since the introduction of the rechargeable mitochondria-targeted antioxidants (RMA). Two major groups have been developing RMA of the MitoQ and SkQ types independently, and many additional trials have been done by other res
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e357589e42c25a636e41d2bef4f465df
https://doi.org/10.1016/b978-0-12-394625-6.00010-6
https://doi.org/10.1016/b978-0-12-394625-6.00010-6