Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Vsevolod Telezhkin"'
Autor:
Qian Liu, Vsevolod Telezhkin, Wenkai Jiang, Yu Gu, Yan Wang, Wei Hong, Weiming Tian, Polina Yarova, Gaofeng Zhang, Simon Ming-yuen Lee, Peng Zhang, Min Zhao, Nicholas D. Allen, Emilio Hirsch, Josef Penninger, Bing Song
Publikováno v:
Cell & Bioscience, Vol 13, Iss 1, Pp 1-17 (2023)
Abstract Background Neural stem cells (NSCs) are considered as candidates for cell replacement therapy in many neurological disorders. However, the propensity for their differentiation to proceed more glial rather than neuronal phenotypes in patholog
Externí odkaz:
https://doaj.org/article/797ccd32264d468c927a159ef5755817
Autor:
Fraser I. Young, Vsevolod Telezhkin, Sarah J. Youde, Martin S. Langley, Maria Stack, Paul J. Kemp, Rachel J. Waddington, Alastair J. Sloan, Bing Song
Publikováno v:
Stem Cells International, Vol 2016 (2016)
Cellular heterogeneity presents an important challenge to the development of cell-based therapies where there is a fundamental requirement for predictable and reproducible outcomes. Transplanted Dental Pulp Stem/Progenitor Cells (DPSCs) have demonstr
Externí odkaz:
https://doaj.org/article/6509d82a57d045c7a208ed29b28e0525
Publikováno v:
British journal of pharmacology, 2020, Vol.177(3), pp.580-599 [Peer Reviewed Journal]
British Journal of Pharmacology
British Journal of Pharmacology
Histamine, acting via distinct histamine H1 , H2 , H3 , and H4 receptors, regulates various physiological and pathological processes, including pain. In the last two decades, there has been a particular increase in evidence to support the involvement
Autor:
Tatyana A. Shelkovnikova, Wenbin Wei, Tetsuro Hirose, Camille Rabesahala de Meritens, Vsevolod Telezhkin, Johnathan Cooper-Knock, Natalia Ninkina, Vladimir L. Buchman, Shinichi Nakagawa, Michail S. Kukharsky, Haiyan An
Publikováno v:
Translational Psychiatry
Translational Psychiatry, Vol 10, Iss 1, Pp 1-19 (2020)
Translational psychiatry, 2020, Vol.10(1), pp.171 [Peer Reviewed Journal]
Translational Psychiatry, Vol 10, Iss 1, Pp 1-19 (2020)
Translational psychiatry, 2020, Vol.10(1), pp.171 [Peer Reviewed Journal]
NEAT1 is a highly and ubiquitously expressed long non-coding RNA (lncRNA) which serves as an important regulator of cellular stress response. However, the physiological role of NEAT1 in the central nervous system (CNS) is still poorly understood. In
Autor:
Justin Durham, Vsevolod Telezhkin, Christopher J. Nile, David N. Edwards, Fréderic Van der Cruyssen, Nontawat Chuinsiri
Publikováno v:
Archives of Oral Biology. 130:105247
Objective This systematic review aims to explore the changes in expression of neuropeptides and/or their receptors following experimental trigeminal neuropathic pain in animals. Design MEDLINE, Embase, and Scopus were searched for publications up to
Autor:
Luned Badder, Andrew D. Randall, Paul J. Kemp, Alis Hughes, Nicholas D. Allen, Daniela Riccardi, Jane M. Hancock, Jonathan T. Brown, Christian Schnell, Charlene Geater, Vsevolod Telezhkin, David Rushton, Annalena Wieland, Polina Yarova, Emma L Cope
Publikováno v:
The Journal of Physiology. 594:6583-6594
Neurons differentiated from pluripotent stem cells using established neural culture conditions often exhibit functional deficits. Recently, we have developed enhanced media which both synchronize the neurogenesis of pluripotent stem cell-derived neur
Autor:
Charlene Geater, Andrew D. Randall, Andrea Comella, Emma L Cope, Alis Hughes, Georgina Bombau, Marco Straccia, Christian Schnell, Philip Sanders, Nicholas D. Allen, Polina Yarova, Jon T. Brown, Natalie Connor-Robson, Vsevolod Telezhkin, Luned Badder, Jane M. Hancock, Belinda A.N. Thompson, Sun Yung, Paul J. Kemp, Josep M. Canals, Shona Joy
Publikováno v:
American Journal of Physiology-Cell Physiology. 310:C520-C541
Although numerous protocols have been developed for differentiation of neurons from a variety of pluripotent stem cells, most have concentrated on being able to specify effectively appropriate neuronal subtypes and few have been designed to enhance o
Autor:
Rachel J. Waddington, Bing Song, Sarah Jane Youde, Vsevolod Telezhkin, Alastair James Sloan, Maria Stack, Martin Simon Langley, Fraser I. Young, Paul J. Kemp
Publikováno v:
Stem Cells International
Stem Cells International, Vol 2016 (2016)
Stem Cells International, Vol 2016 (2016)
Cellular heterogeneity presents an important challenge to the development of cell-based therapies where there is a fundamental requirement for predictable and reproducible outcomes. Transplanted Dental Pulp Stem/Progenitor Cells (DPSCs) have demonstr
Autor:
William R. Ford, Andrea Brancale, Jeremy P.T. Ward, Daniela Riccardi, Salvatore Ferla, Paul J. Kemp, Christopher Corrigan, Kenneth J. Broadley, Polina Yarova, Emma Jane Kidd, Ping Huang, Martin Schepelmann, Vsevolod Telezhkin
Publikováno v:
Airway pharmacology and treatment.
Background: Inhibitors of the extracellular calcium-sensing receptor (CaSR), termed calcilytics, were developed to evoke pulsatile changes in plasma parathyroid hormone (PTH) levels as a novel anti-osteoporotic treatment. Recently we have shown that
Autor:
David Brown, Mónica Pardo, Polina Yarova, Sun Yung, Josep M. Canals, Jonathan T. Brown, Jane M. Hancock, Vsevolod Telezhkin, Nicholas D. Allen, Anne Elizabeth Rosser, Ngoc Nga Vinh, Paul J. Kemp, Gerardo García-Díaz Barriga, Andrew D. Randall, Marco Straccia
Publikováno v:
Pflugers Archiv
Telezhkin, V, Straccia, M, Yarova, P, Pardo, M, Yung, S, Vinh, N N, Hancock, J M, Barriga, G G D, Brown, D A, Rosser, A E, Brown, J T, Canals, J M, Randall, A D, Allen, N D & Kemp, P J 2018, ' Kv7 channels are upregulated during striatal neuron development and promote maturation of human iPSC-derived neurons ', Pflügers Archiv: European Journal of Physiology . https://doi.org/10.1007/s00424-018-2155-7
Telezhkin, V, Straccia, M, Yarova, P, Pardo, M, Yung, S, Vinh, N N, Hancock, J M, Barriga, G G D, Brown, D A, Rosser, A E, Brown, J T, Canals, J M, Randall, A D, Allen, N D & Kemp, P J 2018, ' Kv7 channels are upregulated during striatal neuron development and promote maturation of human iPSC-derived neurons ', Pflügers Archiv: European Journal of Physiology . https://doi.org/10.1007/s00424-018-2155-7
Kv7 channels determine the resting membrane potential of neurons and regulate their excitability. Even though dysfunction of Kv7 channels has been linked to several debilitating childhood neuronal disorders, the ontogeny of the constituent genes, whi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e020e206e8d595605fbd5296feeb145
https://orca.cardiff.ac.uk/id/eprint/111917/1/s00424-018-2155-7.pdf
https://orca.cardiff.ac.uk/id/eprint/111917/1/s00424-018-2155-7.pdf