In Vivo Targeting of Clostridioides difficile Using Phage-Delivered CRISPR-Cas3 Antimicrobials.

Autor: Selle K; Locus Biosciences, Inc., Morrisville, North Carolina, USA., Fletcher JR; Department of Population Health and Pathobiology, College of Veterinary Medicine, North Carolina State University, Raleigh, North Carolina, USA., Tuson H; Locus Biosciences, Inc., Morrisville, North Carolina, USA., Schmitt DS; Locus Biosciences, Inc., Morrisville, North Carolina, USA., McMillan L; Locus Biosciences, Inc., Morrisville, North Carolina, USA., Vridhambal GS; Locus Biosciences, Inc., Morrisville, North Carolina, USA., Rivera AJ; Department of Population Health and Pathobiology, College of Veterinary Medicine, North Carolina State University, Raleigh, North Carolina, USA., Montgomery SA; Department of Pathology and Laboratory Medicine, Lineberger Comprehensive Cancer Center, University of North Carolina School of Medicine, Chapel Hill, North Carolina, USA., Fortier LC; Department of Microbiology and Infectious Diseases, Faculty of Medicine and Health Sciences, Université de Sherbrooke, Sherbrooke, Canada., Barrangou R; Locus Biosciences, Inc., Morrisville, North Carolina, USA rbarran@ncsu.edu cmtherio@ncsu.edu dave@locus-bio.com.; Department of Food, Bioprocessing and Nutrition Sciences, North Carolina State University, Raleigh, North Carolina, USA., Theriot CM; Department of Population Health and Pathobiology, College of Veterinary Medicine, North Carolina State University, Raleigh, North Carolina, USA rbarran@ncsu.edu cmtherio@ncsu.edu dave@locus-bio.com., Ousterout DG; Locus Biosciences, Inc., Morrisville, North Carolina, USA rbarran@ncsu.edu cmtherio@ncsu.edu dave@locus-bio.com.

Publikováno v: MBio [mBio] 2020 Mar 10; Vol. 11 (2). Date of Electronic Publication: 2020 Mar 10.

Emerging applications of phage therapy and fecal virome transplantation for treatment of Clostridioides difficile infection: challenges and perspectives.

Autor: Raeisi, Hamideh¹ (AUTHOR), Noori, Maryam¹ (AUTHOR), Azimirad, Masoumeh¹ (AUTHOR), Mohebbi, Seyed Reza² (AUTHOR), Asadzadeh Aghdaei, Hamid³ (AUTHOR), Yadegar, Abbas¹ (AUTHOR) a.yadegar@sbmu.ac.ir, Zali, Mohammad Reza² (AUTHOR)

Publikováno v: Gut Pathogens. 5/9/2023, Vol. 15 Issue 1, p1-20. 20p.

Engineered CRISPR-Cas systems for the detection and control of antibiotic-resistant infections.

Autor: Wu, Yuye¹ (AUTHOR), Battalapalli, Dheerendranath² (AUTHOR), Hakeem, Mohammed J.³ (AUTHOR), Selamneni, Venkatarao² (AUTHOR), Zhang, Pengfei⁴ (AUTHOR) pfzhang2014@163.com, Draz, Mohamed S.² (AUTHOR) mohamed.draz@case.edu, Ruan, Zhi¹ (AUTHOR) r_z@zju.edu.cn

Publikováno v: Journal of Nanobiotechnology. 12/4/2021, Vol. 19 Issue 1, p1-26. 26p.

CRISPR-Cas System: A New Dawn to Combat Antibiotic Resistance.

Autor: Rafiq MS; MOA Laboratory for Risk Assessment of Quality and Safety of Livestock and Poultry Products, Huazhong Agricultural University, Wuhan, 430070, China., Shabbir MA; Institute of Microbiology, University of Veterinary and Animal Sciences, Lahore, Pakistan., Raza A; Livestock and Dairy Development Department, Punjab, Pakistan., Irshad S; Livestock and Dairy Development Department, Punjab, Pakistan., Asghar A; Institute of Pharmaceutical Sciences, University of Veterinary and Animal Sciences, Lahore, Pakistan., Maan MK; Department of Veterinary Surgery and Pet Sciences, University of Veterinary and Animal Sciences, Lahore, Pakistan., Gondal MA; Institute of Continuing Education and Extension, Cholistan University of Veterinary and Animal Sciences, Bahawalpur, Pakistan., Hao H; MOA Laboratory for Risk Assessment of Quality and Safety of Livestock and Poultry Products, Huazhong Agricultural University, Wuhan, 430070, China. haohaihong@aliyun.com.

Publikováno v: BioDrugs : clinical immunotherapeutics, biopharmaceuticals and gene therapy [BioDrugs] 2024 May; Vol. 38 (3), pp. 387-404. Date of Electronic Publication: 2024 Apr 11.

Unraveling Physical Interactions of Clostridioides difficile with Phage and Phage-Derived Proteins Using In Vitro and Whole-Cell Assays.

Autor: Phothichaisri W; Department of Biochemistry, Faculty of Science, Mahidol University, Bangkok, Thailand., Phetruen T; Department of Biochemistry, Faculty of Science, Mahidol University, Bangkok, Thailand.; Laboratory of Molecular Cell Biology, Center for Excellence in Protein and Enzyme Technology, Faculty of Science, Mahidol University, Bangkok, Thailand., Chankhamhaengdecha S; Department of Biology, Faculty of Science, Mahidol University, Bangkok, Thailand., Janvilisri T; Department of Biochemistry, Faculty of Science, Mahidol University, Bangkok, Thailand., Ounjai P; Department of Biology, Faculty of Science, Mahidol University, Bangkok, Thailand., Fagan RP; School of Biosciences, Florey Institute, University of Sheffield, Sheffield, UK., Chanarat S; Department of Biochemistry, Faculty of Science, Mahidol University, Bangkok, Thailand. sittinan.cha@mahidol.edu.; Laboratory of Molecular Cell Biology, Center for Excellence in Protein and Enzyme Technology, Faculty of Science, Mahidol University, Bangkok, Thailand. sittinan.cha@mahidol.edu.

Publikováno v: Methods in molecular biology (Clifton, N.J.) [Methods Mol Biol] 2024; Vol. 2738, pp. 245-262.