Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Vreni Schneider"'
Autor:
Eleonora Patsenker, Philip Sachse, Andrea Chicca, María Salomé Gachet, Vreni Schneider, Johan Mattsson, Christian Lanz, Mathias Worni, Andrea de Gottardi, Mariam Semmo, Jochen Hampe, Clemens Schafmayer, Rudolf Brenneisen, Jürg Gertsch, Felix Stickel, Nasser Semmo
Publikováno v:
International Journal of Molecular Sciences, Vol 16, Iss 4, Pp 7057-7076 (2015)
The endocannabinoid (EC) system is implicated in many chronic liver diseases, including hepatitis C viral (HCV) infection. Cannabis consumption is associated with fibrosis progression in patients with chronic hepatitis C (CHC), however, the role of E
Externí odkaz:
https://doaj.org/article/ef6088cf5268434d8814fd7d69b3c5d0
Autor:
Johan Mattsson, Felix Stickel, Jochen Hampe, Eleonora Patsenker, Rudolf Brenneisen, Christian Lanz, Mathias Worni, Mariam Semmo, Philip Sachse, Vreni Schneider, Nasser Semmo, Andrea Chicca, Jürg Gertsch, María Salomé Gachet, Andrea De Gottardi, Clemens Schafmayer
Publikováno v:
International Journal of Molecular Sciences
Volume 16
Issue 4
Pages 7057-7076
Patsenker, Eleanora; Sachse, Philip; Chicca, Andrea; Gachet Otanez, Maria Salomé; Schneider, Vreni; Mattsson, Johan; Lanz, Christian; Worni, Mathias; De Gottardi, Andrea; Semmo, Mariam; Hampe, Jochen; Schafmayer, Clemens; Brenneisen, Rudolf Max; Gertsch, Jürg; Stickel, Felix; Semmo, Nasser (2015). Elevated levels of endocannabinoids in chronic hepatitis C may modulate cellular immune response and hepatic stellate cell activation. International journal of molecular sciences, 16(4), pp. 7057-7076. Molecular Diversity Preservation International MDPI 10.3390/ijms16047057
International Journal of Molecular Sciences, Vol 16, Iss 4, Pp 7057-7076 (2015)
Volume 16
Issue 4
Pages 7057-7076
Patsenker, Eleanora; Sachse, Philip; Chicca, Andrea; Gachet Otanez, Maria Salomé; Schneider, Vreni; Mattsson, Johan; Lanz, Christian; Worni, Mathias; De Gottardi, Andrea; Semmo, Mariam; Hampe, Jochen; Schafmayer, Clemens; Brenneisen, Rudolf Max; Gertsch, Jürg; Stickel, Felix; Semmo, Nasser (2015). Elevated levels of endocannabinoids in chronic hepatitis C may modulate cellular immune response and hepatic stellate cell activation. International journal of molecular sciences, 16(4), pp. 7057-7076. Molecular Diversity Preservation International MDPI 10.3390/ijms16047057
International Journal of Molecular Sciences, Vol 16, Iss 4, Pp 7057-7076 (2015)
The endocannabinoid (EC) system is implicated in many chronic liver diseases, including hepatitis C viral (HCV) infection. Cannabis consumption is associated with fibrosis progression in patients with chronic hepatitis C (CHC), however, the role of E
Autor:
Matthias Stoll, Helmut K. Seitz, Gunda Millonig, Felix Stickel, Vreni Schneider, Matthias Ocker, Abbas Agaimy, Eleonora Patsenker, Sebastian Mueller, Rudolf Brenneisen, Till Wissniowski
Publikováno v:
Molecular Medicine. 17:1285-1294
The cannabinoid system (CS) is implicated in the regulation of hepatic fibrosis, steatosis and inflammation, with cannabinoid receptors 1 and 2 (CB1 and CB2) being involved in regulation of pro- and antifibrogenic effects. Daily cannabis smoking is a
Autor:
Gerald Niedobitek, Simon Goodman, Vreni Schneider, Felix Stickel, Yury Popov, Hans Sägesser, Eleonora Patsenker, Detlef Schuppan, M. Ledermann
Publikováno v:
Hepatology. 50:1501-1511
The vitronectin receptor integrin alphavbeta3 promotes angiogenesis by mediating migration and proliferation of endothelial cells, but also drives fibrogenic activation of hepatic stellate cells (HSCs) in vitro. Expecting antifibrotic synergism, we s
Publikováno v:
Journal of Hepatology. 45:786-796
Background/Aims Mammalian target of rapamycin (mTOR) signalling is central in the activation of hepatic stellate cells (HSCs), the key source of extracellular matrix (ECM) in fibrotic liver. We tested the therapeutic potential of the mTOR inhibitor r
Oral imatinib treatment reduces early fibrogenesis but does not prevent progression in the long term
Autor:
Nicolas Widmer, Markus Neef, Bertrand Rochat, M. Ledermann, Juerg Reichen, Vreni Schneider, H. Saegesser, Laurent A. Decosterd
Publikováno v:
Journal of Hepatology. 44:167-175
Background/Aims: Transactivated hepatic stellate cells (HSCs) represent the key source of extra cellular matrix (ECM) in fibrotic liver. Imatinib, a potent inhibitor of the PDGF receptor tyrosine kinase, reduces HSC proliferation and fibrogenesis whe
Publikováno v:
European Journal of Human Genetics. 7:590-598
The large size of many disease genes and the multiplicity of mutations complicate the design of an adequate assay for the identification of disease-causing variants. One of the most successful methods for mutation detection is the single strand confo
Autor:
M. Ledermann, Felix Stickel, Christoph Dorn, Vreni Schneider, Eleonora Patsenker, Claus Hellerbrand, H. Saegesser
Publikováno v:
Journal of hepatology. 55(2)
Background & Aims Recurrence of chronic hepatitis C and progressive fibrosis in liver transplants is frequent and impairs both graft and patient survival. Whether or not the choice of immunosuppression affects progression of fibrosis remains unclear.
Autor:
Vreni Schneider, Christoph H. Österreicher, Thomas Berg, Armin Kolb, Claus Hellerbrand, Helmut K. Seitz, Nils Homann, Helmut Friess, Eleonora Patsenker, Felix Stickel, Julian L. B. Leathart, Detlef Schuppan, Christopher P. Day, J. Halangk, Gero Puhl
Publikováno v:
Alcoholism, clinical and experimental research. 32(6)
BACKGROUND: As only a minority of alcoholics develop cirrhosis, polymorphic genes, whose products are involved in fibrosis development were suggested to confer individual susceptibility. We tested whether a functional promoter polymorphism in the gen
Autor:
Markus Neef, Jürg Reichen, Hans Sägesser, Andrea De Gottardi, Erwin Biecker, Sidney Shaw, M. Ledermann, Vreni Schneider, Matthias Unternährer
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 313(3)
Rapamycin is an immunosuppressant with antiproliferative properties. We investigated whether rapamycin treatment of bile duct-ligated (BDL) rats is capable of inhibiting liver fibrosis and thereby affecting hemodynamics. Following BDL, rats were trea