Single-cell Atlas of Penile Cancer Reveals TP53 Mutations as a Driver of an Aggressive Phenotype, Irrespective of Human Papillomavirus Status, and Provides Clues for Treatment Personalization.

Autor: Elst L; Center for Cancer Biology, Laboratory of Translational Genetics, VIB-KU Leuven, Leuven, Belgium; Department of Urology, University Hospitals Leuven, Leuven, Belgium; Department of Development and Regeneration, KU Leuven, Leuven, Belgium., Philips G; Center for Cancer Biology, Laboratory of Translational Genetics, VIB-KU Leuven, Leuven, Belgium., Vandermaesen K; Center for Cancer Biology, Laboratory of Translational Genetics, VIB-KU Leuven, Leuven, Belgium; Department of Urology, University Hospitals Leuven, Leuven, Belgium; Department of Development and Regeneration, KU Leuven, Leuven, Belgium., Bassez A; Center for Cancer Biology, Laboratory of Translational Genetics, VIB-KU Leuven, Leuven, Belgium., Lodi F; Center for Cancer Biology, Laboratory of Translational Genetics, VIB-KU Leuven, Leuven, Belgium., Vreeburg MTA; Department of Urology, Netherlands Cancer Institute-Antoni van Leeuwenhoek Hospital, Amsterdam, The Netherlands., Brouwer OR; Department of Urology, Netherlands Cancer Institute-Antoni van Leeuwenhoek Hospital, Amsterdam, The Netherlands., Schepers R; Center for Cancer Biology, Laboratory of Translational Genetics, VIB-KU Leuven, Leuven, Belgium., Van Brussel T; Center for Cancer Biology, Laboratory of Translational Genetics, VIB-KU Leuven, Leuven, Belgium., Mohanty SK; Department of Pathology and Laboratory Medicine, Advanced Medical Research Institute, Bhubaneswar, India; Department of Pathology and Laboratory Medicine, CORE Diagnostics, Gurgaon, India., Parwani AV; Department of Pathology, Wexner Medical Center, Columbus, OH, USA., Spans L; Department of Human Genetics, University Hospitals Leuven, Leuven, Belgium., Vanden Bempt I; Department of Human Genetics, University Hospitals Leuven, Leuven, Belgium., Jacomen G; Laboratory of Pathological Anatomy, AZ Sint-Maarten, Mechelen, Belgium., Baldewijns M; Department of Pathology, University Hospitals Leuven, Leuven, Belgium., Lambrechts D; Center for Cancer Biology, Laboratory of Translational Genetics, VIB-KU Leuven, Leuven, Belgium., Albersen M; Department of Urology, University Hospitals Leuven, Leuven, Belgium; Department of Development and Regeneration, KU Leuven, Leuven, Belgium. Electronic address: maarten.albersen@uzleuven.be.

Publikováno v: European urology [Eur Urol] 2024 Aug; Vol. 86 (2), pp. 114-127. Date of Electronic Publication: 2024 Apr 26.

Corporal Skip Metastases in Penile Squamous Cell Carcinoma: An Unknown and Distinct Pattern of Spread with Poor Prognosis.

Autor: Elst L; Department of Urology, University Hospitals Leuven, Leuven, Belgium; Young Academic Urologists Working Group on Penile and Testis Cancer, Arnhem, The Netherlands., Vreeburg MTA; Department of Urology, Netherlands Cancer Institute-Antoni van Leeuwenhoek Hospital, Amsterdam, The Netherlands., de Vries HM; Young Academic Urologists Working Group on Penile and Testis Cancer, Arnhem, The Netherlands; Department of Urology, Netherlands Cancer Institute-Antoni van Leeuwenhoek Hospital, Amsterdam, The Netherlands., Vandermaesen K; Department of Urology, University Hospitals Leuven, Leuven, Belgium., Murphy T; Penile Cancer Centre, St. George's University Hospitals NHS Trust, London, UK., Churchill J; Department of Urology, The Christie NHS Foundation Trust, Manchester, UK., Fallara G; Young Academic Urologists Working Group on Penile and Testis Cancer, Arnhem, The Netherlands; Male Genital Cancer Centre, Department of Urology, NIHR Biomedical Research Centre University College London Hospitals, London, UK; Department of Urology, IRCCS European Institute of Oncology, Milan, Italy., Sanchez D; Department of Urology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA., Falcone M; Department of Urology, Molinette Hospital, University of Torino, AOU Città della Salute e della Scienza di Torino, Turin, Italy., Garcia-Perdomo HA; Division of Urology/Urooncology, Department of Surgery, School of Medicine, Universidad del Valle, Cali, Colombia., Pettaway C; Department of Urology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA., Hakenberg O; Department of Urology, University Medical Center Rostock, Rostock, Germany., Johnstone P; Departments of Radiation Oncology and Urology, Moffitt Cancer Center, Tampa, FL, USA., Spiess PE; Departments of Radiation Oncology and Urology, Moffitt Cancer Center, Tampa, FL, USA., Muneer A; Male Genital Cancer Centre, Department of Urology, NIHR Biomedical Research Centre University College London Hospitals, London, UK., Sangar V; Department of Urology, The Christie NHS Foundation Trust, Manchester, UK., Parnham A; Department of Urology, The Christie NHS Foundation Trust, Manchester, UK., Ayres B; Penile Cancer Centre, St. George's University Hospitals NHS Trust, London, UK., Watkin N; Penile Cancer Centre, St. George's University Hospitals NHS Trust, London, UK., Brouwer OR; Department of Urology, Netherlands Cancer Institute-Antoni van Leeuwenhoek Hospital, Amsterdam, The Netherlands., Albersen M; Department of Urology, University Hospitals Leuven, Leuven, Belgium. Electronic address: maarten.albersen@uzleuven.be.

Publikováno v: European urology oncology [Eur Urol Oncol] 2024 Jun; Vol. 7 (3), pp. 478-484. Date of Electronic Publication: 2023 Oct 07.

Comparison of two hybrid sentinel node tracers: indocyanine green (ICG)- ^99m Tc-nanocolloid vs. ICG- ^99m Tc-nanoscan from a nuclear medicine and surgical perspective.

Autor: Vreeburg MTA; Department of Urology, The Netherlands Cancer Institute-Antoni van Leeuwenhoek Hospital, Amsterdam, The Netherlands.; Interventional Molecular Imaging Laboratory, Department of Radiology, Leiden University Medical Hospital, Leiden, The Netherlands., Azargoshasb S; Department of Urology, The Netherlands Cancer Institute-Antoni van Leeuwenhoek Hospital, Amsterdam, The Netherlands.; Interventional Molecular Imaging Laboratory, Department of Radiology, Leiden University Medical Hospital, Leiden, The Netherlands., van Willigen D; Interventional Molecular Imaging Laboratory, Department of Radiology, Leiden University Medical Hospital, Leiden, The Netherlands., Molenaar T; Interventional Molecular Imaging Laboratory, Department of Radiology, Leiden University Medical Hospital, Leiden, The Netherlands.; Radiochemistry Facility, Department of Radiology, Leiden University Medical Hospital, Leiden, The Netherlands., van Oosterom MN; Department of Urology, The Netherlands Cancer Institute-Antoni van Leeuwenhoek Hospital, Amsterdam, The Netherlands.; Interventional Molecular Imaging Laboratory, Department of Radiology, Leiden University Medical Hospital, Leiden, The Netherlands., Buckle T; Department of Urology, The Netherlands Cancer Institute-Antoni van Leeuwenhoek Hospital, Amsterdam, The Netherlands.; Interventional Molecular Imaging Laboratory, Department of Radiology, Leiden University Medical Hospital, Leiden, The Netherlands., Slof LJ; Department of Urology, The Netherlands Cancer Institute-Antoni van Leeuwenhoek Hospital, Amsterdam, The Netherlands.; Interventional Molecular Imaging Laboratory, Department of Radiology, Leiden University Medical Hospital, Leiden, The Netherlands.; Instrumentele zaken ontwikkeling, facilitair bedrijf, Leiden University Medical Centre, Leiden, The Netherlands., Klop M; Department of Head and Neck Surgery, The Netherlands Cancer Institute-Antoni van Leeuwenhoek Hospital, Amsterdam, The Netherlands., Karakullukcu B; Department of Head and Neck Surgery, The Netherlands Cancer Institute-Antoni van Leeuwenhoek Hospital, Amsterdam, The Netherlands., Donswijk M; Department of Nuclear Medicine, The Netherlands Cancer Institute-Antoni van Leeuwenhoek Hospital, Amsterdam, The Netherlands., van der Poel HG; Department of Urology, The Netherlands Cancer Institute-Antoni van Leeuwenhoek Hospital, Amsterdam, The Netherlands.; Interventional Molecular Imaging Laboratory, Department of Radiology, Leiden University Medical Hospital, Leiden, The Netherlands., van Leeuwen FWB; Department of Urology, The Netherlands Cancer Institute-Antoni van Leeuwenhoek Hospital, Amsterdam, The Netherlands.; Interventional Molecular Imaging Laboratory, Department of Radiology, Leiden University Medical Hospital, Leiden, The Netherlands., Brouwer OR; Department of Urology, The Netherlands Cancer Institute-Antoni van Leeuwenhoek Hospital, Amsterdam, The Netherlands.; Interventional Molecular Imaging Laboratory, Department of Radiology, Leiden University Medical Hospital, Leiden, The Netherlands., Rietbergen DDD; Interventional Molecular Imaging Laboratory, Department of Radiology, Leiden University Medical Hospital, Leiden, The Netherlands. daphnerietbergen@gmail.com.; Department of Radiology, Section Nuclear Medicine, Leiden University Medical Hospital, Leiden, The Netherlands. daphnerietbergen@gmail.com.

Publikováno v: European journal of nuclear medicine and molecular imaging [Eur J Nucl Med Mol Imaging] 2023 Jul; Vol. 50 (8), pp. 2282-2291. Date of Electronic Publication: 2023 Mar 17.