Vps54 Regulates Lifespan and Locomotor Behavior in Adult Drosophila melanogaster

Autor: Emily C. Wilkinson, Emily L. Starke, Scott A. Barbee

Publikováno v: Frontiers in Genetics, Vol 12 (2021)

Vps54 is an integral subunit of the Golgi-associated retrograde protein (GARP) complex, which is involved in tethering endosome-derived vesicles to the trans-Golgi network (TGN). A destabilizing missense mutation in Vps54 causes the age-progressive m

Externí odkaz: https://doaj.org/article/4d22fe19d4c349038ea69be121cfdcb6

Vps54 regulates Drosophila neuromuscular junction development and interacts genetically with Rab7 to control composition of the postsynaptic density

Autor: J. Todd Blankenship, Scott A. Barbee, Malea R. McGimsey, Emily L. Starke, Prajal H. Patel, Emily C. Wilkinson

Publikováno v: Biology Open
article-version (VoR) Version of Record
Biology Open, Vol 9, Iss 8 (2020)

Vps54 is a subunit of the Golgi-associated retrograde protein (GARP) complex, which is involved in tethering endosome-derived vesicles to the trans-Golgi network (TGN). In the wobbler mouse, a model for human motor neuron (MN) disease, reduction in t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::475d9b0bef88a766ee346b5a6aefb520
http://europepmc.org/articles/PMC7473652

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Genetic alterations in Wnt family of genes and their putative association with head and neck squamous cell carcinoma

Autor: Aditya, Jain, Smiline Girija, A. S., Paramasivam, A., Vijayashree Priyadharsini, J.

Publikováno v: Genomics & Informatics

Tamoxifen (TAM) is an anticancer drug used to treat estrogen receptor (ER)‒positive breast cancer. However, its ER-independent cytotoxic and antifungal activities have prompted debates on its mechanism of action. To achieve a better understanding o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59e292013e28da99e7d7300c67de9ada
https://doi.org/10.5808/gi.20065

Vps54 and the wobbler mouse

Autor: Thomas eSchmitt-John

Publikováno v: Schmitt-John, T 2015, ' Vps54 and the wobbler mouse ', Frontiers in Neuroscience, vol. 9, 381 . https://doi.org/10.3389/fnins.2015.00381
Frontiers in Neuroscience, Vol 9 (2015)
Frontiers in Neuroscience

The wobbler mouse is an animal model for human motor neuron disease, such as amyotrophic lateral sclerosis (ALS). The spontaneous, recessive wobbler mutation causes degeneration of upper and lower motor neurons leading to progressive muscle weakness

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2db81fa52b679328b1de534252a14c7
https://pure.au.dk/portal/da/publications/vps54-and-the-wobbler-mouse(0d340568-6c36-431c-8c6d-fb815a351c2d).html