Zobrazeno 1 - 10
of 764
pro vyhledávání: '"Vps34"'
Autor:
Christina J. F. Courreges, Elizabeth C. M. Davenport, Benoit Bilanges, Elena Rebollo-Gomez, Jens Hukelmann, Priya Schoenfelder, James R. Edgar, David Sansom, Cheryl L. Scudamore, Rahul Roychoudhuri, Oliver A. Garden, Bart Vanhaesebroeck, Klaus Okkenhaug
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Regulatory T (Treg) cells are essential for the maintenance of immunological tolerance, yet the molecular components required for their maintenance and effector functions remain incompletely defined. Inactivation of VPS34 in Treg cells led to an earl
Externí odkaz:
https://doaj.org/article/76c0dafb2bb54d09976bae31a2ce382f
Autor:
Wenwen Liu, Kehan Wang, Yuting Lin, Lu Wang, Xin Jin, Yuexin Qiu, Wenya Sun, Ling Zhang, Yan Sun, Xiaowei Dou, Shiming Luo, Youqiang Su, Qingyuan Sun, Wenpei Xiang, Feiyang Diao, Jing Li
Publikováno v:
Advanced Science, Vol 11, Iss 41, Pp n/a-n/a (2024)
Abstract Asynchronous nuclear and cytoplasmic maturation in human oocytes is believed to cause morphological anomalies after controlled ovarian hyperstimulation. Vacuolar protein sorting 34 (VPS34) is renowned for its pivotal role in regulating autop
Externí odkaz:
https://doaj.org/article/ebb0c48010514c60897a8a8e45799d2a
Publikováno v:
Advanced Science, Vol 11, Iss 21, Pp n/a-n/a (2024)
Abstract Vps34 is the unique member of the class III phosphoinositide 3‐kinase family that performs both vesicular transport and autophagy. Its role in natural killer (NK) cells remains uncertain. In this study, a model without Vps34 (Vps34fl/fl/CD
Externí odkaz:
https://doaj.org/article/7089424c9bfb4681b7b4a10bded25ba4
Publikováno v:
Медицинская иммунология, Vol 25, Iss 2, Pp 233-252 (2023)
Previously, autophagy was termed as a mechanism used by the cells with a lack of essential nutrients supporting homeostasis. Over the decade of studies, autophagy proved to be a more complex, ambiguous mechanism. Its activation depends on the nature
Externí odkaz:
https://doaj.org/article/6ebc15f299624ae9a19d5922ea42cbb0
Autor:
Zhenyu Zhao, Zhen Wei, Jiaxin Zheng, Zhihong Li, Hecun Zou, Xiang Wen, Fahong Li, Xueyu Wang, Qian Huang, Huaqing Zeng, Hui Fan, Xuefei Cai, Jiming Zhang, Bei Jia, Ailong Huang, Mengji Lu, Yong Lin
Publikováno v:
Emerging Microbes and Infections, Vol 12, Iss 2 (2023)
Chronic hepatitis B virus (HBV) infection remains one of the major global public health concerns, and it develop into liver fibrosis, cirrhosis, and hepatocellular carcinoma. Recent evidence suggests that endosomal and autophagic vesicles are benefic
Externí odkaz:
https://doaj.org/article/81d600794b4c48c38d85bfc31e91d737
Akademický článek
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Akademický článek
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Akademický článek
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Autor:
Ruei-Liang Yan, Chiu-Lin Luan, Chun-Chieh Liao, Li-Heng Liu, Fei-Yun Chen, Hsin-Yi Chen, Ruey-Hwa Chen
Publikováno v:
Journal of Biomedical Science, Vol 29, Iss 1, Pp 1-19 (2022)
Abstract Background Autophagy plays important roles in cell homeostasis and protein quality control. Long non-coding RNAs (lncRNAs) have been revealed as an emerging class of autophagy regulators, but the majority of them function in regulating the e
Externí odkaz:
https://doaj.org/article/ec67da46af3a4aa8b10acaf8349b1c75
Publikováno v:
Genes and Diseases, Vol 7, Iss 3, Pp 401-407 (2020)
Vps34 (vacuolar protein-sorting 34) plays important role in autophagy and endosomal trafficking. These processes are closely associated protein ubiquitination and degradation. We have hypothesized that Vps34 ubiquitination status would also control i
Externí odkaz:
https://doaj.org/article/8cfe1b822a554d088ad332aaac61130a