Engaging natural antibody responses for the treatment of inflammatory bowel disease via phosphorylcholine-presenting nanofibres.

Autor: Curvino EJ; Department of Biomedical Engineering, Duke University, Durham, NC, USA., Roe EF; Department of Biomedical Engineering, Duke University, Durham, NC, USA., Freire Haddad H; Department of Biomedical Engineering, Duke University, Durham, NC, USA., Anderson AR; Department of Biomedical Engineering, Duke University, Durham, NC, USA., Woodruff ME; Department of Biomedical Engineering, Duke University, Durham, NC, USA., Votaw NL; Department of Biomedical Engineering, Duke University, Durham, NC, USA., Segura T; Department of Biomedical Engineering, Duke University, Durham, NC, USA., Hale LP; Department of Pathology, Duke University Medical Center, Durham, NC, USA., Collier JH; Department of Biomedical Engineering, Duke University, Durham, NC, USA. joel.collier@duke.edu.

Publikováno v: Nature biomedical engineering [Nat Biomed Eng] 2024 May; Vol. 8 (5), pp. 628-649. Date of Electronic Publication: 2023 Nov 27.

HIV envelope antigen valency on peptide nanofibers modulates antibody magnitude and binding breadth.

Autor: Fries CN; Department of Biomedical Engineering, Duke University, 101 Science Dr., Campus, Box 90281, Durham, NC, 27708, USA., Chen JL; Department of Molecular Genetics and Microbiology, Duke University School of Medicine, Durham, NC, 27710, USA.; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC, 27710, USA., Dennis ML; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC, 27710, USA., Votaw NL; Department of Biomedical Engineering, Duke University, 101 Science Dr., Campus, Box 90281, Durham, NC, 27708, USA., Eudailey J; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC, 27710, USA., Watts BE; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC, 27710, USA., Hainline KM; Department of Biomedical Engineering, Duke University, 101 Science Dr., Campus, Box 90281, Durham, NC, 27708, USA., Cain DW; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC, 27710, USA., Barfield R; Department of Biostatistics and Bioinformatics, Duke University School of Medicine, Durham, NC, 27710, USA., Chan C; Department of Biostatistics and Bioinformatics, Duke University School of Medicine, Durham, NC, 27710, USA., Moody MA; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC, 27710, USA.; Department of Pediatrics, Duke University Medical Center, Duke University School of Medicine, Box 103020, Durham, NC, 27710, USA.; Department of Immunology, Duke University School of Medicine, Durham, NC, 27710, USA., Haynes BF; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC, 27710, USA.; Department of Immunology, Duke University School of Medicine, Durham, NC, 27710, USA., Saunders KO; Department of Molecular Genetics and Microbiology, Duke University School of Medicine, Durham, NC, 27710, USA.; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC, 27710, USA.; Department of Immunology, Duke University School of Medicine, Durham, NC, 27710, USA.; Department of Surgery, Duke University School of Medicine, Durham, NC, 27710, USA., Permar SR; Department of Molecular Genetics and Microbiology, Duke University School of Medicine, Durham, NC, 27710, USA.; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC, 27710, USA.; Department of Pediatrics, Duke University Medical Center, Duke University School of Medicine, Box 103020, Durham, NC, 27710, USA.; Department of Immunology, Duke University School of Medicine, Durham, NC, 27710, USA.; Department of Pediatrics, New York-Presbyterian/Weill Cornell Medicine, New York, NY, 10065, USA., Fouda GG; Department of Molecular Genetics and Microbiology, Duke University School of Medicine, Durham, NC, 27710, USA. genevieve.fouda@duke.edu.; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC, 27710, USA. genevieve.fouda@duke.edu.; Department of Pediatrics, Duke University Medical Center, Duke University School of Medicine, Box 103020, Durham, NC, 27710, USA. genevieve.fouda@duke.edu., Collier JH; Department of Biomedical Engineering, Duke University, 101 Science Dr., Campus, Box 90281, Durham, NC, 27708, USA. joel.collier@duke.edu.; Department of Immunology, Duke University School of Medicine, Durham, NC, 27710, USA. joel.collier@duke.edu.

Publikováno v: Scientific reports [Sci Rep] 2021 Jul 14; Vol. 11 (1), pp. 14494. Date of Electronic Publication: 2021 Jul 14.

Modular complement assemblies for mitigating inflammatory conditions.

Autor: Hainline KM; Biomedical Engineering Department, Duke University, Durham, NC 27708., Shores LS; Biomedical Engineering Department, Duke University, Durham, NC 27708., Votaw NL; Biomedical Engineering Department, Duke University, Durham, NC 27708., Bernstein ZJ; Biomedical Engineering Department, Duke University, Durham, NC 27708., Kelly SH; Biomedical Engineering Department, Duke University, Durham, NC 27708., Fries CN; Biomedical Engineering Department, Duke University, Durham, NC 27708., Madhira MS; Biomedical Engineering Department, Duke University, Durham, NC 27708., Gilroy CA; Biomedical Engineering Department, Duke University, Durham, NC 27708., Chilkoti A; Biomedical Engineering Department, Duke University, Durham, NC 27708., Collier JH; Biomedical Engineering Department, Duke University, Durham, NC 27708 joel.collier@duke.edu.

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2021 Apr 13; Vol. 118 (15).

Biomaterial strategies for generating therapeutic immune responses.

Autor: Kelly SH; Duke University, Department of Biomedical Engineering, United States., Shores LS; Duke University, Department of Biomedical Engineering, United States., Votaw NL; Duke University, Department of Biomedical Engineering, United States., Collier JH; Duke University, Department of Biomedical Engineering, United States. Electronic address: joel.collier@duke.edu.

Publikováno v: Advanced drug delivery reviews [Adv Drug Deliv Rev] 2017 May 15; Vol. 114, pp. 3-18. Date of Electronic Publication: 2017 Apr 25.