Spatiotemporal segregation of human marginal zone and memory B cell populations in lymphoid tissue

Autor: Yuan Zhao, Mohamed Uduman, Jacqueline H. Y. Siu, Thomas J. Tull, Jeremy D. Sanderson, Yu-Chang Bryan Wu, Julian Q. Zhou, Nedyalko Petrov, Richard Ellis, Katrina Todd, Konstantia-Maria Chavele, William Guesdon, Anna Vossenkamper, Wayel Jassem, David P. D’Cruz, David J. Fear, Susan John, Dagmar Scheel-Toellner, Claire Hopkins, Estefania Moreno, Natalie L. Woodman, Francesca Ciccarelli, Susanne Heck, Steven H. Kleinstein, Mats Bemark, Jo Spencer

Publikováno v: Nature Communications, Vol 9, Iss 1, Pp 1-15 (2018)

Human memory and marginal zone B cells share some features including CD27 expression and somatic hypermutation, but their lineage relationship is still unclear. Here the authors use mass cytometry and sequential clustering methods to show that, despi

Externí odkaz: https://doaj.org/article/18e17622ab574decbfaad7cce6011bef

Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.

Reduced CD27−IgD− B Cells in Blood and Raised CD27−IgD− B Cells in Gut-Associated Lymphoid Tissue in Inflammatory Bowel Disease

Autor: Pararasa, Chathyan, Zhang, Na, Tull, Thomas Justin, Chong, Ming HA, Siu, Jacqueline HY, Guesdon, William Wilfried Jonathan, Chavele, Konstantia-Maria, Sanderson, Jeremy, Langmead, Louise, Kok, Klaartje, Spencer, Jo Michele, vossenkamper, anna

Publikováno v: Frontiers in Immunology
Pararasa, C, Zhang, N, Tull, T J, Chong, M HA, Siu, J HY, Guesdon, W W J, Chavele, K-M, Sanderson, J, Langmead, L, Kok, K, Spencer, J M & vossenkamper, A 2019, ' Reduced CD27-IgD-B cells in blood and raised CD27-IgD-B cells in gut-associated lymphoid tissue in inflammatory bowel disease. ', Frontiers in Immunology, vol. 10, 361 . https://doi.org/10.3389/fimmu.2019.00361

The intestinal mucosa in inflammatory bowel disease (IBD) contains increased frequencies of lymphocytes and a disproportionate increase in plasma cells secreting immunoglobulin (Ig)G relative to other isotypes compared to healthy controls. Despite co

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::150b67ac90f975b989d69cf37e362438
http://europepmc.org/articles/PMC6411645

Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.

Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.