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Discovery of nostatin A, an azole-containing proteusin with prominent cytostatic and pro-apoptotic activity.

Autor: Delawská K; Centre Algatech, Institute of Microbiology, Czech Academy of Sciences, Novohradká 237, Centre Algatech, Institute of Microbiology, Czech Academy of Sciences, 379 01 Třeboň, Czech Republic. hrouzek@alga.cz.; Department of Medical Biology, Faculty of Science, University of South Bohemia, Branišovská 1645/31a, 370 05 České Budějovice, Czech Republic., Hájek J; Centre Algatech, Institute of Microbiology, Czech Academy of Sciences, Novohradká 237, Centre Algatech, Institute of Microbiology, Czech Academy of Sciences, 379 01 Třeboň, Czech Republic. hrouzek@alga.cz., Voráčová K; Centre Algatech, Institute of Microbiology, Czech Academy of Sciences, Novohradká 237, Centre Algatech, Institute of Microbiology, Czech Academy of Sciences, 379 01 Třeboň, Czech Republic. hrouzek@alga.cz., Kuzma M; Laboratory of Molecular Structure Characterization, Institute of Microbiology, Czech Academy of Sciences, Vídeňská 1083, 142 00 Praha 4, Czech Republic., Mareš J; Centre Algatech, Institute of Microbiology, Czech Academy of Sciences, Novohradká 237, Centre Algatech, Institute of Microbiology, Czech Academy of Sciences, 379 01 Třeboň, Czech Republic. hrouzek@alga.cz.; Institute of Hydrobiology, Biology Centre of the Czech Academy of Sciences, Na Sádkách 702/7, 370 05 České Budějovice, Czech Republic., Vicková K; Centre Algatech, Institute of Microbiology, Czech Academy of Sciences, Novohradká 237, Centre Algatech, Institute of Microbiology, Czech Academy of Sciences, 379 01 Třeboň, Czech Republic. hrouzek@alga.cz., Kádek A; Laboratory of Structural Biology and Cell Signaling, Institute of Microbiology, Czech Academy of Sciences, Vídeňská 1083, 142 00 Praha 4, Czech Republic., Tučková D; Centre Algatech, Institute of Microbiology, Czech Academy of Sciences, Novohradká 237, Centre Algatech, Institute of Microbiology, Czech Academy of Sciences, 379 01 Třeboň, Czech Republic. hrouzek@alga.cz.; Department of Medical Biology, Faculty of Science, University of South Bohemia, Branišovská 1645/31a, 370 05 České Budějovice, Czech Republic., Gallob F; CeMM - Research Center for Molecular Medicine, Austrian Academy of Sciences, Lazarettgasse 14, 1090 Wien, Austria., Divoká P; Centre Algatech, Institute of Microbiology, Czech Academy of Sciences, Novohradká 237, Centre Algatech, Institute of Microbiology, Czech Academy of Sciences, 379 01 Třeboň, Czech Republic. hrouzek@alga.cz.; Department of Medical Biology, Faculty of Science, University of South Bohemia, Branišovská 1645/31a, 370 05 České Budějovice, Czech Republic., Moos M; Institute of Entomology, Laboratory of Analytical Biochemistry and Metabolomics, Biology Centre of the Czech Academy of Sciences, Branišovská 1160/31, 370 05, České Budějovice, Czech Republic., Opekar S; Institute of Entomology, Laboratory of Analytical Biochemistry and Metabolomics, Biology Centre of the Czech Academy of Sciences, Branišovská 1160/31, 370 05, České Budějovice, Czech Republic., Koch L; Institute of Pharmacy, Freie Universität Berlin, Königin-Luise-Str. 2+4, 14195 Berlin, Germany.; Institute of Pharmacy, Martin Luther University Halle-Wittenberg, Hoher Weg 8, 06120 Halle, (Saale), Germany., Saurav K; Centre Algatech, Institute of Microbiology, Czech Academy of Sciences, Novohradká 237, Centre Algatech, Institute of Microbiology, Czech Academy of Sciences, 379 01 Třeboň, Czech Republic. hrouzek@alga.cz., Sedlák D; Institute of Molecular Genetics, Czech Academy of Sciences, Vídeňská 1083, 142 20 Praha., Novák P; Laboratory of Structural Biology and Cell Signaling, Institute of Microbiology, Czech Academy of Sciences, Vídeňská 1083, 142 00 Praha 4, Czech Republic., Urajová P; Centre Algatech, Institute of Microbiology, Czech Academy of Sciences, Novohradká 237, Centre Algatech, Institute of Microbiology, Czech Academy of Sciences, 379 01 Třeboň, Czech Republic. hrouzek@alga.cz., Dean J; Centre Algatech, Institute of Microbiology, Czech Academy of Sciences, Novohradká 237, Centre Algatech, Institute of Microbiology, Czech Academy of Sciences, 379 01 Třeboň, Czech Republic. hrouzek@alga.cz., Gažák R; Laboratory of Antibiotic Resistance and Microbial Metabolomics, Institute of Microbiology, Czech Academy of Sciences, Vídeňská 1083, 142 00 Praha 4, Czech Republic., Niedermeyer TJH; Institute of Pharmacy, Freie Universität Berlin, Königin-Luise-Str. 2+4, 14195 Berlin, Germany.; Institute of Pharmacy, Martin Luther University Halle-Wittenberg, Hoher Weg 8, 06120 Halle, (Saale), Germany., Kameník Z; Laboratory of Antibiotic Resistance and Microbial Metabolomics, Institute of Microbiology, Czech Academy of Sciences, Vídeňská 1083, 142 00 Praha 4, Czech Republic., Šimek P; Institute of Entomology, Laboratory of Analytical Biochemistry and Metabolomics, Biology Centre of the Czech Academy of Sciences, Branišovská 1160/31, 370 05, České Budějovice, Czech Republic., Villunger A; CeMM - Research Center for Molecular Medicine, Austrian Academy of Sciences, Lazarettgasse 14, 1090 Wien, Austria.; Institute for Developmental Immunology, Medical University of Innsbruck, Biocenter, Innsbruck, Austria., Hrouzek P; Centre Algatech, Institute of Microbiology, Czech Academy of Sciences, Novohradká 237, Centre Algatech, Institute of Microbiology, Czech Academy of Sciences, 379 01 Třeboň, Czech Republic. hrouzek@alga.cz.

Publikováno v: Organic & biomolecular chemistry [Org Biomol Chem] 2024 Nov 22. Date of Electronic Publication: 2024 Nov 22.