Neutrophil count, lymphocyte count and neutrophil-to-lymphocyte ratio in relation to response to adjunctive dexamethasone treatment in community-acquired pneumonia

Autor: Wittermans, Esther, van de Garde, Ewoudt MW, Voorn, G Paul, Aldenkamp, Arnoud F, Janssen, Rob, Grutters, Jan C, Bos, Willem Jan W

Publikováno v: In European Journal of Internal Medicine February 2022 96:102-108

Continuation of connecting orbits in 3D-ODEs: (II) Cycle-to-cycle connections

Autor: Doedel, E. J., Kooi, B. W., Kuznetsov, Yu. A., van Voorn, G. A. K.

Publikováno v: Int. J. Bifurcation & Chaos 19 (2009), 159-169

In Part I of this paper we discussed new methods for the numerical continuation of point-to-cycle connecting orbits in 3-dimensional autonomous ODE's using projection boundary conditions. In this second part we extend the method to the numerical cont

Externí odkaz: http://arxiv.org/abs/0804.0179

Overweight and obesity are not associated with worse clinical outcomes in COVID-19 patients treated with fixed-dose 6 mg dexamethasone

Autor: Wittermans, Esther, Grutters, Jan C., Moeniralam, Hazra S., Ocak, Gurbey, Paul Voorn, G., Bos, Willem Jan W., van de Garde, Ewoudt M.W., Afd Pharmacoepi & Clinical Pharmacology, Pharmacoepidemiology and Clinical Pharmacology

Publikováno v: International Journal of Obesity, 46(11), 2000-2005. SPRINGERNATURE
International Journal of Obesity, 46(11), 2000. Nature Publishing Group

Objective: A fixed 6 mg dexamethasone dose for 10 days is the standard treatment for all hospitalised COVID-19 patients who require supplemental oxygen. Yet, the pharmacokinetic properties of dexamethasone can lead to diminishing systemic dexamethaso

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92ad3857bf7f82e4acb14b050b1d8b7d
https://doi.org/10.1038/s41366-022-01204-1

Community-acquired pneumonia subgroups and differential response to corticosteroids: a secondary analysis of controlled studies

Autor: Wittermans, Esther, van der Zee, Philip A, Qi, Hongchao, van de Garde, Ewoudt M W, Blum, Claudine A, Christ-Crain, Mirjam, Gommers, Diederik, Grutters, Jan C, Voorn, G Paul, Bos, Willem Jan W, Endeman, Henrik, Afd Pharmacoepi & Clinical Pharmacology, Pharmacoepidemiology and Clinical Pharmacology

Publikováno v: ERJ Open Research, 8(1):00489-2021. European Respiratory Society
ERJ Open Research, 8(1). EUROPEAN RESPIRATORY SOC JOURNALS LTD
ERJ Open Research, 8(1), 1. European Respiratory Society
ERJ Open Research
article-version (VoR) Version of Record

Background Latent class analysis (LCA) has identified subgroups with meaningful treatment implications in acute respiratory distress syndrome. We performed a secondary analysis of three studies to assess whether LCA can identify clinically distinct s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b3f17a20afc8a8fd075e272ea6ed259
https://doi.org/10.1183/23120541.00489-2021

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