Zobrazeno 1 - 10
of 208
pro vyhledávání: '"Vooijs, P"'
Autor:
Anaís Sánchez-Castillo, Kim G. Savelkouls, Alessandra Baldini, Judith Hounjet, Pierre Sonveaux, Paulien Verstraete, Kim De Keersmaecker, Barbara Dewaele, Benny Björkblom, Beatrice Melin, Wendy Y. Wu, Rickard L. Sjöberg, Kasper M. A. Rouschop, Martijn P. G. Broen, Marc Vooijs, Kim R. Kampen
Publikováno v:
Oncogenesis, Vol 13, Iss 1, Pp 1-18 (2024)
Abstract The serine/glycine (ser/gly) synthesis pathway branches from glycolysis and is hyperactivated in approximately 30% of cancers. In ~13% of glioblastoma cases, we observed frequent amplifications and rare mutations in the gene encoding the enz
Externí odkaz:
https://doaj.org/article/d61b57eb4ce140da832cf94a49f0efd8
Publikováno v:
BMC Public Health, Vol 21, Iss 1, Pp 1-10 (2021)
Abstract Background Work participation is an important determinant of public health; being unemployed leads to a decrease in an individual’s health. In the Netherlands, people with a work disability can apply for disability benefits, in which peopl
Externí odkaz:
https://doaj.org/article/0fc1f6e0ce954746989d492efc980888
Autor:
Lorena Giuranno, Eloy M. Roig, Carolien Wansleeben, Annette van denBerg, Arjan J. Groot, Ludwig Dubois, Marc Vooijs
Publikováno v:
Stem Cells Translational Medicine, Vol 9, Iss 7, Pp 799-812 (2020)
Abstract Hyperactivity of the NOTCH pathway is associated with tumor growth and radiotherapy resistance in lung cancer, and NOTCH/γ‐secretase inhibitors (GSIs) are a potential therapeutic target. The therapeutic outcome, however, is often restrict
Externí odkaz:
https://doaj.org/article/5940253b822140699faa623d3186f1dc
Autor:
Tom G. Keulers, Sten F. Libregts, Joel E.J. Beaumont, Kim G. Savelkouls, Johan Bussink, Hans Duimel, Ludwig Dubois, Marijke I. Zonneveld, Carmen López‐Iglesias, Karel Bezstarosti, Jeroen A. Demmers, Marc Vooijs, Marca Wauben, Kasper M.A. Rouschop
Publikováno v:
Journal of Extracellular Vesicles, Vol 10, Iss 14, Pp n/a-n/a (2021)
Abstract Tumour hypoxia is a hallmark of solid tumours and contributes to tumour progression, metastasis development and therapy resistance. In response to hypoxia, tumour cells secrete pro‐angiogenic factors to induce blood vessel formation and re
Externí odkaz:
https://doaj.org/article/af6b9ede953b475aa1ad89c65bcf4ab4
Autor:
Giuranno, Lorena, Piepers, Jolanda A F, Korsten, Evelien, Borman, Reitske, van de Kamp, Gerarda, De Ruysscher, Dirk, Essers, Jeroen, Vooijs, Marc A
Publikováno v:
Stem Cells Translational Medicine; September 2024, Vol. 13 Issue: 9 p927-939, 13p
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
Patient-derived cancer organoids have taken a prominent role in pre-clinical and translational research and have been generated for most common solid tumors. Cancer organoids have been shown to retain key genetic and phenotypic characteristics of the
Externí odkaz:
https://doaj.org/article/805ded051e514f6dac6533af7306a530
Autor:
Jenny A. F. Vermeer, Jonathan Ient, Bostjan Markelc, Jakob Kaeppler, Lydie M. O. Barbeau, Arjan J. Groot, Ruth J. Muschel, Marc A. Vooijs
Publikováno v:
Disease Models & Mechanisms, Vol 13, Iss 7 (2020)
Intratumoural hypoxia is a common characteristic of malignant treatment-resistant cancers. However, hypoxia-modification strategies for the clinic remain elusive. To date, little is known on the behaviour of individual hypoxic tumour cells in their m
Externí odkaz:
https://doaj.org/article/06c80dc265d14a17aca588930a6cf945
Publikováno v:
BMC Medical Education, Vol 18, Iss 1, Pp 1-9 (2018)
Abstract Background To evaluate whether a training programme is a feasible approach to facilitate occupational health professionals’ (OHPs) use of knowledge and skills provided by a guideline. Methods Feasibility was evaluated by researching three
Externí odkaz:
https://doaj.org/article/281474a5fea54c739ec6baa39b97b3e2
Autor:
Aniek A. O. M. Claassen, Cornelia H. M. van den Ende, Jorit J. L. Meesters, Sanne Pellegrom, Brigitte M. Kaarls-Ohms, Jacoba Vooijs, Gerardine E. M. P. Willemsen-de Mey, Thea P. M. Vliet Vlieland
Publikováno v:
BMC Health Services Research, Vol 18, Iss 1, Pp 1-9 (2018)
Abstract Background The aim of this randomized controlled trial was to evaluate the effect of a ‘supply on demand’-distribution strategy, compared to an ‘unsolicited supply’-distribution strategy, on the use of a care booklet and clinical out
Externí odkaz:
https://doaj.org/article/fcafd95ff6d04ccaa8c878909445eac1
Autor:
Judith Hounjet, Marc Vooijs
Publikováno v:
Biomolecules, Vol 11, Iss 9, p 1369 (2021)
Aberrant Notch signaling has been found in a broad range of human malignancies. Consequently, small molecule inhibitors and antibodies targeting Notch signaling in human cancers have been developed and tested; however, these have failed due to limite
Externí odkaz:
https://doaj.org/article/dc3a17199d394f4296682a22f2cd1668