Ultrastructural Localization of the Mannose 6-Phosphate Receptor in Rat Liver

Autor: Geuze, H. J., Slot, J. W., Hasilik, A., Von Figura, K.

Publikováno v: The Journal of Cell Biology, 1984 Jun 01. 98(6), 2047-2054.

Externí odkaz: https://www.jstor.org/stable/1610876

Molecular Cloning of the Mouse Lysosomal Acid Phosphatase

Autor: von Figura K, Geier C, Regina Pohlmann

Publikováno v: Biological Chemistry Hoppe-Seyler. 372:301-304

The mouse cDNA for lysosomal acid phosphatase was cloned. The deduced amino-acid sequence shows 89 and 96% identity with that of the human and rat enzyme, respectively. Namely all residues known to be important for the structure, catalytic activity a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7592b99ddb99dacca67ef492c2470d9
https://doi.org/10.1515/bchm3.1991.372.1.301

Efficacy of enzyme replacement therapy in alpha-mannosidosis mice: a preclinical animal study

Autor: Roces, D. P., Lullmann Rauch, R., Peng, J., Balducci, Chiara, Andersson, C., Tollersrud, O., Fogh, J., Orlacchio, Aldo, Beccari, Tommaso, Saftig, P., Von Figura, K.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______3982::dbd29675b8c422b3312d326835fdd847
http://hdl.handle.net/11391/161931

Functions of cathepsin K in bone resorption:Lessons from cathepsin K deficient mice

Autor: Saftig, P., Hunziker, E., Everts, V., Jones, S., Boyde, A., Wehmeyer, O., Suter, A., von Figura, K.

Publikováno v: Saftig, P, Hunziker, E, Everts, V, Jones, S, Boyde, A, Wehmeyer, O, Suter, A & von Figura, K 2000, Functions of cathepsin K in bone resorption : Lessons from cathepsin K deficient mice . in J Langner & S Ansorge (eds), Cellular Peptidases in Immune Functions and Diseases 2 . Kluwer Academic Publishers, New York, pp. 293-300, International Conference on Cellular Peptidases in Immune Functions and Diseases (II), 1/01/00 . https://doi.org/10.1007/0-306-46826-3_32

Cathepsin K is a cysteine proteinase expressed predominantly in osteoclasts. Cathepsin K cleaves key bone matrix proteins and is believed to play an important role in degrading the organic phase of bone during bone resorption. Pycnodysostosis, an aut

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______4612::d0b134e32192fce09cc656bb436eeb75
https://research.vu.nl/en/publications/dc3987dc-fa4d-4b30-8039-e01c6cf140a6

Early embryonic death of mice deficient in gamma-adaptin

Autor: Zizioli, Daniela, Meyer, C, Guhde, G, Saftig, P, VON FIGURA, K, Schu, P.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______3662::41bee977b9a188d19ddcdd1a9e55768c
http://hdl.handle.net/11379/7447