Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Volodymyr Horishny"'
Autor:
Ivan Sydorenko, Serhii Holota, Andrii Lozynskyi, Yulian Konechnyi, Volodymyr Horishny, Andriy Karkhut, Svyatoslav Polovkovych, Olexandr Karpenko, Roman Lesyk
Publikováno v:
Molbank, Vol 2022, Iss 4, p M1478 (2022)
Multicomponent reactions effectively contribute to modern organic and medicinal chemistry. 4-Thiazolidinone core and cyclopropyl moiety are important structural motifs for design of potential biologically active molecules. In the present paper, the c
Externí odkaz:
https://doaj.org/article/e246e79f58384ceaaed63f9edf48155f
Publikováno v:
Pharmacia, Vol 68, Iss 1, Pp 195-200 (2021)
The reaction of 1H-benzoimidazole-2-carbaldehyde with 4-oxo-2-thioxothiazolidin-3-ylcarboxilic acids was studied and the combinatorial library of 5-(1H-benzoimidazol-2-ylmethylene)-4-oxo-2-thioxothiazolidin-3-ylcarboxilic acids has been prepared. The
Externí odkaz:
https://doaj.org/article/af97097f87dc4c5a865ab16161add11a
Autor:
Volodymyr Horishny, Athina Geronikaki, Victor Kartsev, Vasyl Matiychuk, Anthi Petrou, Pavel Pogodin, Vladimir Poroikov, Theodora A. Papadopoulou, Ioannis S. Vizirianakis, Marina Kostic, Marija Ivanov, Marina Sokovic
Publikováno v:
Molecules, Vol 27, Iss 3, p 1068 (2022)
Background: Infectious diseases represent a significant global strain on public health security and impact on socio-economic stability all over the world. The increasing resistance to the current antimicrobial treatment has resulted in the crucial ne
Externí odkaz:
https://doaj.org/article/f6d82d3c16ad4a6cb4f4414432973959
Autor:
Volodymyr Horishny, Victor Kartsev, Vasyl Matiychuk, Athina Geronikaki, Petrou Anthi, Pavel Pogodin, Vladimir Poroikov, Marija Ivanov, Marina Kostic, Marina D. Soković, Phaedra Eleftheriou
Publikováno v:
Pharmaceuticals, Vol 13, Iss 9, p 229 (2020)
Herein we report the design, synthesis, computational, and experimental evaluation of the antimicrobial activity of fourteen new 3-amino-5-(indol-3-yl) methylene-4-oxo-2-thioxothiazolidine derivatives. The structures were designed, and their antimicr
Externí odkaz:
https://doaj.org/article/c8efefc811ab4db9a31cb44114a74b50
Autor:
Volodymyr Horishny, Victor Kartsev, Athina Geronikaki, Vasyl Matiychuk, Anthi Petrou, Jasmina Glamoclija, Ana Ciric, Marina Sokovic
Publikováno v:
Molecules, Vol 25, Iss 8, p 1964 (2020)
Background: Infectious diseases symbolize a global consequential strain on public health security and impact on the socio-economic stability all over the world. The increasing resistance to the current antimicrobial treatment has resulted in crucial
Externí odkaz:
https://doaj.org/article/dba6af76905b4110b239cd78c316f1df
Publikováno v:
Acta Crystallographica Section E, Vol 69, Iss 3, Pp o391-o391 (2013)
The structural analysis of the title compound, C14H14N2O4S, particularly the presence of an acetyl group at the exocyclic N atom and the C(H)—C(O2CMe)—N acetoxy group in the thiazole ring, may indicate that one of the starting materials, i.e. 2-(
Externí odkaz:
https://doaj.org/article/3629b1fa52534d378f16c62de80b4f1b
Publikováno v:
Acta Crystallographica Section E, Vol 69, Iss 3, Pp o356-o357 (2013)
The title compound, C15H16N2O5S, is a product of the reaction of 2-(2,4-dimethoxyphenylamino)-1,3-thiazol-4(5H)-one with acetic anhydride. The presence of the acetyl and acetoxy groups in the molecule indicates that the starting thiazole exists as a
Externí odkaz:
https://doaj.org/article/25948b3b3f2046e7a586304dd4352a32
Publikováno v:
Pharmaceutical Sciences, Vol 27, Iss 3, Pp 353-365 (2021)
Background: Nonsteroidal anti-inflammatory drugs (NSAIDs) are among the most commonly used drugs in the world. The widespread use of NSAIDs is associated with a number of serious side effects and complications observed for both selective and non-sele
Autor:
Volodymyr Horishny
Publikováno v:
Biointerface Research in Applied Chemistry. 11:12434-12446
In our present work, we reported an effective synthesis, molecular docking, and antimicrobial properties of novel 5-(4-substituted-benzyl)-2-(furan/thiophen-2-ylmethylene hydrazono) thiazolidin-4-ones (6a-g) and (7a-i). The structures of the synthesi
Publikováno v:
Pharmacia 68(1): 195-200
Pharmacia, Vol 68, Iss 1, Pp 195-200 (2021)
Pharmacia, Vol 68, Iss 1, Pp 195-200 (2021)
The reaction of 1H-benzoimidazole-2-carbaldehyde with 4-oxo-2-thioxothiazolidin-3-ylcarboxilic acids was studied and the combinatorial library of 5-(1H-benzoimidazol-2-ylmethylene)-4-oxo-2-thioxothiazolidin-3-ylcarboxilic acids has been prepared. The