Zobrazeno 1 - 10
of 70
pro vyhledávání: '"Volkmar, Heinrich"'
Autor:
Dah Som Kim, Joleen S. Cheah, Tzu Wei Lai, Karen X. Zhao, Skylar R. Foust, Yuh-Ru Julie Lee, Su Hao Lo, Volkmar Heinrich, Soichiro Yamada
Publikováno v:
Cell Reports, Vol 43, Iss 7, Pp 114480- (2024)
Summary: The cytoskeleton of the cell is constantly exposed to physical forces that regulate cellular functions. Selected members of the LIM (Lin-11, Isl-1, and Mec-3) domain-containing protein family accumulate along force-bearing actin fibers, with
Externí odkaz:
https://doaj.org/article/69caa2fdf41540a4b0a2a01fdd161698
Autor:
Elena Boero, Ronald D. Gorham, Emmet A. Francis, Jonathan Brand, Lay Heng Teng, Dennis J. Doorduijn, Maartje Ruyken, Remy M. Muts, Christian Lehmann, Admar Verschoor, Kok P. M. van Kessel, Volkmar Heinrich, Suzan H. M. Rooijakkers
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-17 (2023)
Abstract The complement system provides vital immune protection against infectious agents by labeling them with complement fragments that enhance phagocytosis by immune cells. Many details of complement-mediated phagocytosis remain elusive, partly be
Externí odkaz:
https://doaj.org/article/f3257d792e8348a29273436ad98c183c
Autor:
Emmet A Francis, Volkmar Heinrich
Publikováno v:
PLoS Computational Biology, Vol 18, Iss 8, p e1009937 (2022)
The dynamic interplay between cell adhesion and protrusion is a critical determinant of many forms of cell motility. When modeling cell spreading on adhesive surfaces, traditional mathematical treatments often consider passive cell adhesion as the pr
Externí odkaz:
https://doaj.org/article/ea381def85e94939a7fa0e1b37668be0
Publikováno v:
Biophysical Journal. 121:4714-4728
Complex motions of immune cells are an integral part of diapedesis, chemotaxis, phagocytosis, and other vital processes. To better understand how immune cells execute such motions, we present a detailed analysis of phagocytic spreading of human neutr
Autor:
Volkmar Heinrich, Kyle A. Jacobs, Joleen S Cheah, Jacqueline L Yee, Shuji Ueda, Tzu Wei Lai, Reca Caballelo, Soichiro Yamada
Publikováno v:
Molecular Biology of the Cell
Molecular biology of the cell, vol 32, iss 13
Molecular biology of the cell, vol 32, iss 13
Sensing physical forces is a critical first step in mechano-transduction of cells. Zyxin, a LIM domain-containing protein, is recruited to force-bearing actin filaments and is thought to repair and strengthen them. Yet, the precise force-induced prot
Publikováno v:
Frontiers in Immunology, Vol 8 (2017)
The ability of motile immune cells to detect and follow gradients of chemoattractant is critical to numerous vital functions, including their recruitment to sites of infection and—in emerging immunotherapeutic applications—to malignant tumors. Fa
Externí odkaz:
https://doaj.org/article/64a77a02c6da4f898ad4adc986a93669
Autor:
Elena, Boero, Ronald D, Gorham, Emmet A, Francis, Jonathan, Brand, Lay Heng, Teng, Dennis J, Doorduijn, Maartje, Ruyken, Remy M, Muts, Christian, Lehmann, Admar, Verschoor, Kok P M, van Kessel, Volkmar, Heinrich, Suzan H M, Rooijakkers
Publikováno v:
Scientific reports. 13(1)
The complement system provides vital immune protection against infectious agents by labeling them with complement fragments that enhance phagocytosis by immune cells. Many details of complement-mediated phagocytosis remain elusive, partly because it
Autor:
Emmet A. Francis, Volkmar Heinrich
Publikováno v:
PLoS computational biology, vol 18, iss 8
The dynamic interplay between cell adhesion and protrusion is a critical determinant of many forms of cell motility. When modeling cell spreading on adhesive surfaces, traditional mathematical treatments often consider passive cell adhesion as the pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bdb002899cb708a89611f557a853cb33
https://doi.org/10.1101/2022.03.01.482589
https://doi.org/10.1101/2022.03.01.482589
Autor:
Cheng-Yuk Lee, George R Thompson, Christine J Hastey, Gregory C Hodge, Jennine M Lunetta, Demosthenes Pappagianis, Volkmar Heinrich
Publikováno v:
PLoS ONE, Vol 10, Iss 6, p e0129522 (2015)
Coccidioides spp. are dimorphic pathogenic fungi whose parasitic forms cause coccidioidomycosis (Valley fever) in mammalian hosts. We use an innovative interdisciplinary approach to analyze one-on-one encounters between human neutrophils and two form
Externí odkaz:
https://doaj.org/article/0980decc58df46468cba361305a09491
Publikováno v:
Biophysical Journal. 121:375a-376a