Zobrazeno 1 - 10
of 209
pro vyhledávání: '"Volkhard A J Kempf"'
Autor:
Alexander A Dichter, MSc, Tilman G Schultze, PhD, Anne Wenigmann, BSc, Wibke Ballhorn, Andreas Latz, PhD, Elif Schlüfter, BSc, Palmira Ventosilla, MSc, Humberto Guerra Allison, PhD, Cesar Ugarte-Gil, PhD, Pablo Tsukayama, ProfPhD, Volkhard A J Kempf, ProfMD
Publikováno v:
The Lancet Microbe, Vol 2, Iss 12, Pp e685-e694 (2021)
Summary: Background: Bartonella bacilliformis is the aetiological agent of Carrión's disease, a biphasic and highly lethal illness formerly restricted to the South American Andes that is now spreading to adjacent areas. Reliable serodiagnostic appro
Externí odkaz:
https://doaj.org/article/c1bf22ff51f446bdbe6a00e3c60c79d6
Autor:
Philip G Ferstl, Natalie Filmann, Eva-Maria Heilgenthal, Andreas A Schnitzbauer, Wolf O Bechstein, Volkhard A J Kempf, David Villinger, Tilman G Schultze, Michael Hogardt, Christoph Stephan, Haitham Mutlak, Nina Weiler, Marcus M Mücke, Jonel Trebicka, Stefan Zeuzem, Oliver Waidmann, Martin-Walter Welker
Publikováno v:
PLoS ONE, Vol 16, Iss 1, p e0245091 (2021)
ObjectivesRising prevalence of multidrug-resistant organisms (MDRO) is a major health problem in patients with liver cirrhosis. The impact of MDRO colonization in liver transplantation (LT) candidates and recipients on mortality has not been determin
Externí odkaz:
https://doaj.org/article/57c50735b5b0475e99df823b65e46513
Autor:
Jan A Stratmann, Raphael Lacko, Olivier Ballo, Shabnam Shaid, Wolfgang Gleiber, Maria J G T Vehreschild, Thomas Wichelhaus, Claudia Reinheimer, Stephan Göttig, Volkhard A J Kempf, Peter Kleine, Susanne Stera, Christian Brandts, Martin Sebastian, Sebastian Koschade
Publikováno v:
PLoS ONE, Vol 15, Iss 11, p e0242544 (2020)
ObjectivesMultidrug-resistant organisms (MDRO) are considered an emerging threat worldwide. Data covering the clinical impact of MDRO colonization in patients with solid malignancies, however, is widely missing. We sought to determine the impact of M
Externí odkaz:
https://doaj.org/article/bffd8075374f4d809c14b4e40601ffda
Autor:
Chun Kew, Cristian Prieto-Garcia, Anshu Bhattacharya, Manuela Tietgen, Craig R. MacNair, Lindsey A. Carfrae, João Mello-Vieira, Stephan Klatt, Yi-Lin Cheng, Rajeshwari Rathore, Elise Gradhand, Ingrid Fleming, Man-Wah Tan, Stephan Göttig, Volkhard A. J. Kempf, Ivan Dikic
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-13 (2024)
Abstract Acinetobacter baumannii is a pathogenic and multidrug-resistant Gram-negative bacterium that causes severe nosocomial infections. To better understand the mechanism of pathogenesis, we compare the proteomes of uninfected and infected human c
Externí odkaz:
https://doaj.org/article/cc857566b9914285a523bd2ab2b86cfe
Autor:
Sebastian Scheich, Rosalie Koenig, Anne C Wilke, Sarah Lindner, Claudia Reinheimer, Thomas A Wichelhaus, Michael Hogardt, Volkhard A J Kempf, Johanna Kessel, Sarah Weber, Hans Martin, Gesine Bug, Hubert Serve, Björn Steffen
Publikováno v:
PLoS ONE, Vol 13, Iss 7, p e0201169 (2018)
Allogeneic hematopoietic stem cell transplantation (allo-HSCT) offers potential cure to acute myeloid leukemia (AML) patients. However, infections with commensal bacteria are an important cause for non-relapse mortality (NRM). We have previously desc
Externí odkaz:
https://doaj.org/article/240619bb961043aeaf804f9dbc60a50c
Autor:
Maja Stepanić, Sanja Duvnjak, Irena Reil, Suzana Hađina, Volkhard A. J. Kempf, Silvio Špičić, Željko Mihaljević, Relja Beck
Publikováno v:
Parasites & Vectors, Vol 17, Iss 1, Pp 1-13 (2024)
Abstract Background Cats are the primary reservoirs of the bacterium Bartonella henselae, the main cause of cat-scratch disease in humans. The main vector of the bacterium is the cat flea, Ctenocephalides felis. In southeastern Europe, data are lacki
Externí odkaz:
https://doaj.org/article/94941b1367fc497e8dde28346691cdf1
Activation of hypoxia inducible factor 1 is a general phenomenon in infections with human pathogens.
Autor:
Nadine Werth, Christiane Beerlage, Christian Rosenberger, Amir S Yazdi, Markus Edelmann, Amro Amr, Wanja Bernhardt, Christof von Eiff, Karsten Becker, Andrea Schäfer, Andreas Peschel, Volkhard A J Kempf
Publikováno v:
PLoS ONE, Vol 5, Iss 7, p e11576 (2010)
BACKGROUND: Hypoxia inducible factor (HIF)-1 is the key transcriptional factor involved in the adaptation process of cells and organisms to hypoxia. Recent findings suggest that HIF-1 plays also a crucial role in inflammatory and infectious diseases.
Externí odkaz:
https://doaj.org/article/aa3fdf8ba14f421cafbf9f1e986ea066
Autor:
Pawel Szczesny, Dirk Linke, Astrid Ursinus, Kerstin Bär, Heinz Schwarz, Tanja M Riess, Volkhard A J Kempf, Andrei N Lupas, Jörg Martin, Kornelius Zeth
Publikováno v:
PLoS Pathogens, Vol 4, Iss 8, p e1000119 (2008)
Trimeric autotransporter adhesins (TAAs) are a major class of proteins by which pathogenic proteobacteria adhere to their hosts. Prominent examples include Yersinia YadA, Haemophilus Hia and Hsf, Moraxella UspA1 and A2, and Neisseria NadA. TAAs also
Externí odkaz:
https://doaj.org/article/bfe5bc0db5984d03a3ef307430abe2e1
Autor:
Helene A Haeberle, Carin Dürrstein, Peter Rosenberger, Yashoda M Hosakote, Johannes Kuhlicke, Volkhard A J Kempf, Roberto P Garofalo, Holger K Eltzschig
Publikováno v:
PLoS ONE, Vol 3, Iss 10, p e3352 (2008)
BACKGROUND: Hypoxia-inducible factor 1 (HIF)-1alpha is a transcription factor that functions as master regulator of mammalian oxygen homeostasis. In addition, recent studies identified a role for HIF-1alpha as transcriptional regulator during inflamm
Externí odkaz:
https://doaj.org/article/714a0b4620244231b5333e056a48d9a8
Autor:
Shogo Yoshimoto, Satoshi Ishii, Ayane Kawashiri, Taishi Matsushita, Dirk Linke, Stephan Göttig, Volkhard A. J. Kempf, Madoka Takai, Katsutoshi Hori
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 12 (2024)
Gram-negative bacterium Acinetobacter sp. Tol 5 exhibits high adhesiveness to various surfaces of general materials, from hydrophobic plastics to hydrophilic glass and metals, via AtaA, an Acinetobacter trimeric autotransporter adhesin Although the a
Externí odkaz:
https://doaj.org/article/a6c22f4e0cd141228702f9eb9cbe26b6