Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Volker Winstel"'
Autor:
Eva Happ, Kora Schulze, Zinia Afrin, Sabrina Woltemate, Pia Görner, Stefan Ziesing, Dirk Schlüter, Robert Geffers, Volker Winstel, Marius Vital
Publikováno v:
Gut Microbes, Vol 16, Iss 1 (2024)
We investigated consequences of resistance acquisition in Escherichia coli clinical isolates during anaerobic (continuous culture) growth and examined their sensitivity to butyrate, a hallmark metabolite of healthy gut microbiota. Strains were strati
Externí odkaz:
https://doaj.org/article/efa98febc02f4ef1823f72ca3994f28b
Publikováno v:
eLife, Vol 12 (2024)
Host-directed therapy (HDT) is an emerging approach to overcome antimicrobial resistance in pathogenic microorganisms. Specifically, HDT targets host-encoded factors required for pathogen replication and survival without interfering with microbial gr
Externí odkaz:
https://doaj.org/article/f6c1a284a29349ac958201def6e900ae
Publikováno v:
PLoS Pathogens, Vol 19, Iss 12, p e1011892 (2023)
Staphylococcus aureus is a dangerous pathogen that evolved refined immuno-evasive strategies to antagonize host immune responses. This involves the biogenesis of death-effector deoxyribonucleosides, which kill infectious foci-penetrating macrophages.
Externí odkaz:
https://doaj.org/article/0acd097b0bf94cbe8629880df87e803e
Autor:
Nicoletta Schwermann, Volker Winstel
Publikováno v:
Frontiers in Microbiology, Vol 14 (2023)
Surface proteins of Gram-positive pathogens are key determinants of virulence that substantially shape host-microbe interactions. Specifically, these proteins mediate host invasion and pathogen transmission, drive the acquisition of heme-iron from he
Externí odkaz:
https://doaj.org/article/d4d2ff74384a4e4eabafd1b2fb6025fa
Autor:
Dorothea Bünsow, Eshraq Tantawy, Tjorven Ostermeier, Heike Bähre, Annette Garbe, Jesper Larsen, Volker Winstel
Publikováno v:
Virulence, Vol 12, Iss 1, Pp 989-1002 (2021)
Methicillin-resistant Staphylococcus pseudintermedius (MRSP) is an emerging zoonotic pathogen of canine origin that causes an array of fatal diseases, including bacteremia and endocarditis. Despite large-scale genome sequencing projects have gained s
Externí odkaz:
https://doaj.org/article/be6bbdd3d8d24be2a325ac0aee5177c2
Autor:
Eshraq Tantawy, Nicoletta Schwermann, Tjorven Ostermeier, Annette Garbe, Heike Bähre, Marius Vital, Volker Winstel
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Adenosine synthase A (AdsA) is a key virulence factor of Staphylococcus aureus, a dangerous microbe that causes fatal diseases in humans. Together with staphylococcal nuclease, AdsA generates deoxyadenosine (dAdo) from neutrophil extracellular DNA tr
Externí odkaz:
https://doaj.org/article/b88c243c4aba4aad8aa24f35a5147ead
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
NETosis is a multi-facetted cellular process that promotes the formation of neutrophil extracellular traps (NETs). NETs as web-like structures consist of DNA fibers armed with granular proteins, histones, and microbicidal peptides, thereby exhibiting
Externí odkaz:
https://doaj.org/article/23b21838f0fc4701843405f036f5c039
Autor:
Lenka Fišarová, Tibor Botka, Xin Du, Ivana Mašlaňová, Pavol Bárdy, Roman Pantůček, Martin Benešík, Pavel Roudnický, Volker Winstel, Jesper Larsen, Ralf Rosenstein, Andreas Peschel, Jiří Doškař
Publikováno v:
mSphere, Vol 6, Iss 3 (2021)
Multidrug-resistant strains of S. epidermidis
Externí odkaz:
https://doaj.org/article/ba1ae2ad9e924e17b78fcb465a63c7e4
Autor:
Dominique Missiakas, Volker Winstel
Publikováno v:
Frontiers in Immunology, Vol 11 (2021)
Host cell death programs are fundamental processes that shape cellular homeostasis, embryonic development, and tissue regeneration. Death signaling and downstream host cell responses are not only critical to guide mammalian development, they often ac
Externí odkaz:
https://doaj.org/article/df29856cd74e409aa4f8a86263d147f6
Publikováno v:
mBio, Vol 10, Iss 6 (2019)
ABSTRACT Staphylococcus aureus is a deadly pathogen that causes fatal diseases in humans. During infection, S. aureus secretes nuclease (Nuc) and adenosine synthase A (AdsA) to generate cytotoxic deoxyadenosine (dAdo) from neutrophil extracellular tr
Externí odkaz:
https://doaj.org/article/96ced280a7214751a3686edfdb0d8892