Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Volker Unger"'
Publikováno v:
Zentralblatt für Veterinärmedizin Reihe A. 24:298-310
Zusammenfassung Biochemische, hamatologische und gerinnungsphysiologische Werte wurden bei 125 Kalbern beiderlei Geschlechts — Alter zwischen 8 und 16 Wochen, Gewicht zwischen 80 und 120 kg — ermittelt. Es wurden Kalber der Deutsch-Schwarzbunte R
Autor:
Christian Grosse-Siestrup, Volker Unger, David A. Groneberg, Gustav Schäcke, Renate Wrbitzky, Miriam Molliné, Dirk Pleimes, Michael Pfaff
Publikováno v:
Zentralblatt für Arbeitsmedizin, Arbeitsschutz und Ergonomie. 57:58-65
Die Leber steht als zentrales Organ der Entgiftung im Zentrum von Effekten exogen zugefuhrter Substanzen und ist deswegen von entscheidender Bedeutung fur die arbeitsmedizinische und umweltmedizinische Toxikologie. Gerade in letzter Zeit wurden Effek
Publikováno v:
Physiological Measurement. 27:1167-1175
Isolated porcine kidneys are commonly used to study physiological and pathophysiological aspects of renal homeostasis but standardized evaluation procedures of renal function in this model do not exist so far. A double-logarithmical nomogram is estab
Autor:
David A. Groneberg, Stefan Nagel, Jochen Springer, Christian Grosse-Siestrup, Christian Witt, Q. Thai Dinh, Anke Wussow, Volker Unger, Jeanette Pfeffer
Publikováno v:
Archives of Toxicology. 78:697-705
Polidocanol is an effective sclerosing agent that consists of 95% hydroxypolyethoxydodecane and 5% ethyl alcohol and is known to have a low risk of complications. However, since the compound has been proposed for the local treatment of liver diseases
Autor:
Hans von Baeyer, Wolfram Haider, David Quarcoo, Christian Grosse-Siestrup, Claudia Fehrenberg, Volker Unger, Roland Schmitt, David A. Groneberg
Publikováno v:
Nephron Physiology. 96:p52-p58
Reperfusion injuries after organ transplantation affect graft function and influence long-term graft survival. As hypothermic storage, which minimizes the extent of unspecific tissue injury after ischemia and reperfusion, is significantly influenced
Autor:
Claudia Fehrenberg, Joachim Höchel, Dörte Lehmann, Volker Unger, David A. Groneberg, Christian Große-Siestrup
Publikováno v:
Nephrology Dialysis Transplantation. 18:1748-1754
Background The isolated perfused canine kidney has been established as a valid model for conducting both renal physiology and transplantation research. This model is of particular importance for developing new strategies to improve graft function aft
Autor:
Michael Meissler, Christian Peiser, Christian Grosse-Siestrup, Axel Fischer, Roland Schmitt, Stefan Nagel, Anke Wussow, Volker Unger, David A. Groneberg
Publikováno v:
Journal of Pharmaceutical Sciences. 92:1147-1154
Mammalian models of isolated perfused kidneys provide an important tool to study pharmacological, toxicological, and physiological properties of drugs, hormones, and vasoactive substances. As organs from small laboratory animals are difficult to comp
Autor:
David A. Groneberg, Christian Grosse-Siestrup, Stefan Nagel, Axel Fischer, Christian Witt, Jeanette Pfeffer, Volker Unger
Publikováno v:
Toxicologic Pathology. 30:749-754
Different models of isolated and perfused livers and precision cut liver slices have been developed for studies on liver toxicology the past years. As most of these models were limited by nonphysiologi c settings, a new model of normothermic hemoperf
Autor:
David A. Groneberg, Volker Unger, Frank Schäper, Christian Grosse-Siestrup, Claudia Fehrenberg, Axel Fischer, Hans von Baeyer
Publikováno v:
Scopus-Elsevier
Background: The rapidly evolving field of transplantation research with a focus on ischemic and reperfusion injuries has gained importance since the methodology of organ preservation significantly limits graft survival. Numerous models of isolated pe
Autor:
Michael Meissler, Stefan Nagel, Jeannette Pfeffer, Christian Grosse-Siestrup, David A. Groneberg, Volker Unger, Axel Fischer
Publikováno v:
Journal of Pharmacological and Toxicological Methods. 46:163-168
Introduction: Current models of isolated and perfused livers are limited by nonphysiologic perfusates or the need for the use of high numbers of laboratory animals. The present study was performed in order to rectify these difficulties. Methods: To e