Zobrazeno 1 - 10
of 182
pro vyhledávání: '"Volker M. Lauschke"'
Autor:
Lin Guo, JiaTing Ma, MingXuan Xiao, JiaYi Liu, ZhiYu Hu, Shuang Xia, Ning Li, Yan Yang, Hui Gong, Yang Xi, Rao Fu, Pei Jiang, ChunGuang Xia, Volker M. Lauschke, Miao Yan
Publikováno v:
Cell Death and Disease, Vol 15, Iss 8, Pp 1-17 (2024)
Abstract Crizotinib carries an FDA hepatotoxicity warning, yet analysis of the FAERS database suggests that the severity of its hepatotoxicity risks, including progression to hepatitis and liver failure, might be underreported. However, the underlyin
Externí odkaz:
https://doaj.org/article/bff8f09712a34b1792439dcb586fdc0c
Autor:
Evgeniya Mickols, Alina Meyer, Niklas Handin, Malin Stüwe, Jens Eriksson, Jakob Rudfeldt, Kristin Blom, Mårten Fryknäs, Mikael E. Sellin, Volker M. Lauschke, Maria Karlgren, Per Artursson
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract 3D spheroids of primary human hepatocytes (3D PHH) retain a differentiated phenotype with largely conserved metabolic function and proteomic fingerprint over weeks in culture. As a result, 3D PHH are gaining importance as a model for mechani
Externí odkaz:
https://doaj.org/article/14b6909630ac42c4af6b2cef75b8a422
Autor:
Mahamadou D. Camara, Yitian Zhou, Taís Nóbrega De Sousa, José P. Gil, Abdoulaye A. Djimde, Volker M. Lauschke
Publikováno v:
Human Genomics, Vol 18, Iss 1, Pp 1-11 (2024)
Abstract Background CYP2C8 is responsible for the metabolism of 5% of clinically prescribed drugs, including antimalarials, anti-cancer and anti-inflammatory drugs. Genetic variability is an important factor that influences CYP2C8 activity and modula
Externí odkaz:
https://doaj.org/article/10429f4cf3614b199d3bd062f38c841f
Autor:
Lu Pan, Paolo Parini, Roman Tremmel, Joseph Loscalzo, Volker M. Lauschke, Bradley A. Maron, Paola Paci, Ingemar Ernberg, Nguan Soon Tan, Zehuan Liao, Weiyao Yin, Sundararaman Rengarajan, Xuexin Li, The SCA Consortium
Publikováno v:
Genome Biology, Vol 25, Iss 1, Pp 1-21 (2024)
Abstract Single-cell sequencing datasets are key in biology and medicine for unraveling insights into heterogeneous cell populations with unprecedented resolution. Here, we construct a single-cell multi-omics map of human tissues through in-depth cha
Externí odkaz:
https://doaj.org/article/bfac2c6a06f6422a8ceb3444a8f601fb
Autor:
Yi Zhong, Volker M. Lauschke
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 9, Iss 1, Pp 1-2 (2024)
Externí odkaz:
https://doaj.org/article/8ed17d194a5a4f42ab6f0141b8e80ab8
Autor:
Emanuela Talamonti, Jelena Davegardh, Anastasia Kalinovich, Sten M.M. van Beek, Nodi Dehvari, Carina Halleskog, Hamza M. Bokhari, Dana S. Hutchinson, Seungmin Ham, Laura J. Humphrys, Nicola C. Dijon, Aikaterini Motso, Anna Sandstrom, Evelyn Zacharewicz, Ilga Mutule, Edgars Suna, Jana Spura, Karolina Ditrychova, Leigh A. Stoddart, Nicholas D. Holliday, Shane C. Wright, Volker M. Lauschke, Soren Nielsen, Camilla Scheele, Elizabeth Cheesman, Joris Hoeks, Peter Molenaar, Roger J. Summers, Benjamin Pelcman, Gopala K. Yakala, Tore Bengtsson
Publikováno v:
Molecular Metabolism, Vol 85, Iss , Pp 101931- (2024)
Objective: Simultaneous activation of β2- and β3-adrenoceptors (ARs) improves whole-body metabolism via beneficial effects in skeletal muscle and brown adipose tissue (BAT). Nevertheless, high-efficacy agonists simultaneously targeting these recept
Externí odkaz:
https://doaj.org/article/3d4a3a5490234ea7a397025d54414624
Autor:
Gayane Hrachia Buniatian, Ute Schwinghammer, Roman Tremmel, Holger Cynis, Thomas S. Weiss, Ralf Weiskirchen, Volker M. Lauschke, Sonia Youhanna, Isbaal Ramos, Maria Valcarcel, Torgom Seferyan, Jens‐Ulrich Rahfeld, Vera Rieckmann, Kathrin Klein, Marine Buadze, Victoria Weber, Valentina Kolak, Rolf Gebhardt, Scott L. Friedman, Ulrike C. Müller, Matthias Schwab, Lusine Danielyan
Publikováno v:
Advanced Science, Vol 11, Iss 18, Pp n/a-n/a (2024)
Abstract The hepatic content of amyloid beta (Aβ) decreases drastically in human and rodent cirrhosis highlighting the importance of understanding the consequences of Aβ deficiency in the liver. This is especially relevant in view of recent advance
Externí odkaz:
https://doaj.org/article/a502efb1c1864047b669d0f146231d64
Autor:
Peter Harris, Javad Kaveh, Aurino M. Kemas, Henrik Mikaelsson, Matthew Fielden, Volker M. Lauschke, Reza Zandi Shafagh
Publikováno v:
Advanced Materials Interfaces, Vol 11, Iss 14, Pp n/a-n/a (2024)
Abstract Facile, durable and biocompatible integration of hybrid Lab‐on‐a‐Chip devices has remained an important challenge in microengineering. Here, the robust and seamless integration of off‐stoichiometry thiol‐ene‐epoxy (OSTE+) thermos
Externí odkaz:
https://doaj.org/article/2370f091de814307ab727b5e4bef66c0
Autor:
Francesca Lazzeri-Barcelo, Nuria Oliva-Vilarnau, Marion Baniol, Barbara Leibiger, Olaf Bergmann, Volker M. Lauschke, Ingo B. Leibiger, Noah Moruzzi, Per-Olof Berggren
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract Longitudinal monitoring of liver function in vivo is hindered by the lack of high-resolution non-invasive imaging techniques. Using the anterior chamber of the mouse eye as a transplantation site, we have established a platform for longitudi
Externí odkaz:
https://doaj.org/article/2eda5aaab39e4b1b93164e67176e1475
Publikováno v:
Human Genomics, Vol 17, Iss 1, Pp 1-5 (2023)
Externí odkaz:
https://doaj.org/article/ad5873c6493545e0bc9bdfebcedbfc16